Promethazine DM (dextromethorphan / promethazine) and Alcohol / Food Interactions
There is 1 alcohol/food/lifestyle interaction with Promethazine DM (dextromethorphan / promethazine):
dextromethorphan ↔ Alcohol (Ethanol)
Moderate Drug Interaction
Using dextromethorphan together with promethazine may increase side effects such as dizziness, drowsiness, confusion, and difficulty concentrating. Some people, especially the elderly, may also experience impairment in thinking, judgment, and motor coordination. You should avoid or limit the use of alcohol while being treated with these medications. Also avoid activities requiring mental alertness such as driving or operating hazardous machinery until you know how the medications affect you. Talk to your doctor if you have any questions or concerns. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
dextromethorphan ↔ Alcohol (Ethanol)
Moderate Drug Interaction
Using dextromethorphan together with ethanol can increase nervous system side effects such as dizziness, drowsiness, and difficulty concentrating. Some people may also experience impairment in thinking and judgment. You should avoid or limit the use of alcohol while being treated with dextromethorphan. Do not use more than the recommended dose of dextromethorphan, and avoid activities requiring mental alertness such as driving or operating hazardous machinery until you know how the medication affects you. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medication without first talking to your doctor.
promethazine ↔ Alcohol (Ethanol)
Moderate Drug Interaction
Ask your doctor before using promethazine together with ethanol. This can cause uncontrollable movements, agitation, seizures, severe dizziness or fainting, coma, very deep sleep, irregular heartbeats, and high or low body temperature. Use caution when driving, operating machinery, or performing other hazardous activities, these medicaions may cause dizziness or drowsiness. If you experience dizziness or drowsiness, avoid these activities. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Promethazine DM (dextromethorphan / promethazine) drug Interactions
There are 1127 drug interactions with Promethazine DM (dextromethorphan / promethazine)
Promethazine DM (dextromethorphan / promethazine) disease Interactions
There are 20 disease interactions with Promethazine DM (dextromethorphan / promethazine) which include:
- Anticholinergic Effects
- Acute Alcohol Intoxication
- Cardiovascular Disease
- Cns Depression
- Head Injury
- Antidopaminergic Effects 1
- Asthma
- Asthma/Copd
- Psychiatric Conditions
- Breast Cancer
- Dystonic Reactions
- Hematologic Toxicity
- Liver Disease
- Nms
- Parkinsonism
- Renal Dysfunction
- Respiratory Disorders
- Seizure Disorders
- Tardive Dyskinesia
- Antidopaminergic Effects 2
See also...
Drug Interaction Classification
The classifications below are a general guideline only. It is difficult to determine the relevance of a particular drug interaction to any individual given the large number of variables.
| Major | Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. |
| Moderate | Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. |
| Minor | Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. |
Do not stop taking any medications without consulting your healthcare provider.
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