Dextromethorphan Interactions
There are 368 drugs known to interact with dextromethorphan, along with 1 alcohol/food interaction. Of the total drug interactions, 78 are major, 288 are moderate, and 2 are minor.
- View all 368 medications that may interact with dextromethorphan
- View dextromethorphan alcohol/food interactions (1)
Most frequently checked interactions
View interaction reports for dextromethorphan and the medicines listed below.
- Adderall (amphetamine / dextroamphetamine)
- Alcohol (contained in alcoholic beverages) (ethanol)
- Aleve (naproxen)
- Allegra (fexofenadine)
- Benadryl (diphenhydramine)
- Claritin (loratadine)
- CoQ10 (ubiquinone)
- Cymbalta (duloxetine)
- Eliquis (apixaban)
- Fish Oil (omega-3 polyunsaturated fatty acids)
- Flonase (fluticasone nasal)
- Lexapro (escitalopram)
- Metoprolol Succinate ER (metoprolol)
- MiraLAX (polyethylene glycol 3350)
- Mucinex (guaifenesin)
- Paracetamol (acetaminophen)
- Paxlovid (nirmatrelvir / ritonavir)
- Pepto-Bismol (bismuth subsalicylate)
- Probiotic Formula (bifidobacterium infantis / lactobacillus acidophilus)
- Singulair (montelukast)
- Tylenol (acetaminophen)
- Vitamin B12 (cyanocobalamin)
- Vitamin C (ascorbic acid)
- Vitamin D3 (cholecalciferol)
- Vyvanse (lisdexamfetamine)
- Wellbutrin XL (bupropion)
- Xanax (alprazolam)
- Zofran (ondansetron)
- Zoloft (sertraline)
- Zyrtec (cetirizine)
Dextromethorphan alcohol/food interactions
There is 1 alcohol/food interaction with dextromethorphan.
Report options
More about dextromethorphan
- dextromethorphan consumer information
- Compare alternatives
- Pricing & coupons
- Reviews (387)
- Drug images
- Side effects
- Dosage information
- During pregnancy
- Support group
- Drug class: antitussives
- Breastfeeding
Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
See also:
Benadryl
Benadryl is an antihistamine and is used to treat sneezing, runny nose, itching and other ...
Mucinex
Mucinex (guaifenesin) is used to relieve the symptoms of cough and loosen mucus in the chest ...
Botox
Botox is used for cosmetic purposes and to treat overactive bladder symptoms, urinary incontinence ...
Norco
Norco (acetaminophen and hydrocodone) is used to relieve moderate to severe pain. Includes Norco ...
Dilaudid
Dilaudid (hydromorphone) is a narcotic pain reliever used to treat moderate to severe pain ...
Vicodin
Vicodin (acetaminophen and hydrocodone) is used to relieve moderate to severe pain. Includes ...
Acetaminophen/hydrocodone
The combination of hydrocodone and acetaminophen is used to relieve moderate to severe pain ...
Codeine
Codeine is a opioid pain medicine used to treat mild to moderate pain. Includes codeine side ...
Hydromorphone
Hydromorphone systemic is used for anesthetic adjunct, chronic pain, cough, pain
Guaifenesin
Guaifenesin is an expectorant. It helps loosen congestion in your chest and throat. Includes ...
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
