Dextromethorphan use while Breastfeeding
Medically reviewed by Drugs.com. Last updated on Apr 1, 2023.
Drugs containing Dextromethorphan: Auvelity, Promethazine DM, Bromfed DM, Mucinex DM, Delsym, Nuedexta, Robitussin Cough + Chest Congestion DM, Vicks NyQuil Cold & Flu Nighttime Relief, Vicks NyQuil Severe Cold & Flu, Vicks DayQuil Severe Cold & Flu, Show all 1029 »Vicks Dayquil Cold & Flu Relief, Cough & Cold Relief, Dry Cough, Tussin DM, Delsym 12 Hour Cough Relief, Dexcon-DM, Dimetapp Children's Cold & Cough, Robitussin Nighttime Cough DM, Robitussin Cough & Allergy, Tusnel, Codral Cold and Flu + Cough Day and Night, Mucinex Fast-Max Severe Cold, Resperal-DM, Tylenol Cold, Night Time Cold & Flu, Tylenol Cold & Flu Severe, Cough Syrup DM, Buckley's Mixture Cough Suppressant, DexAlone, Capron DMT, Delsym Cough & Sore Throat, Cold Multi-Symptom (Daytime), Abatuss DMX, Tusicof, Vicks NyQuil Cold & Flu Nighttime Relief (Alcohol Free), Alka-Seltzer Plus Severe Cold & Flu Formula Effervescent Tablets, Vicks NyQuil HBP Cold & Flu, Vicks Nyquil D Cold and Flu Nighttime Relief, Comtrex Cold & Cough, Vicks Children’s NyQuil Cold & Cough, Coricidin HBP Cough & Cold, Polytussin DM, Tanafed DMX, Vicks Nyquil Cough, Robafen DM, Coricidin HBP Chest Congestion & Cough, Mucus Relief DM, Tusnel Diabetic, Benylin Expectorant, Deconex DMX, Duraphen Forte, Capmist DM, Capron DM, Coricidin HBP Maximum Strength Flu, Tylenol Cold Multi-Symptom Severe, Sudafed PE Cold & Cough, Cold & Cough Childrens, Donatussin DM Drops, Triphenicol, Bisolvon Dry, Zyncof, Chest Congestion Relief DM, Pres Gen, PanMist DM, Triaminic Multi-Symptom Fever, Coricidin HBP Multi-Symptom Cold (Night), Theraflu Flu & Cough, Allpanto-S, Diabetic Tussin Night Time Formula, NyCair, Mucinex Fast-Max Cold, Flu & Sore Throat, Mucinex Nightshift Severe Cold and Flu, NoHist DM, Alahist CF, Pertussin DM, Delsym 12 Hour Cough Relief for Children & Adults, Strepsils Cough, Robitussin Cough Long-Acting, Scot-Tussin Diabetes, Robitussin CoughGels Long-Acting, Naldecon DX Liquigel, Creo-Terpin, Tussi-Organidin-DM, Mucinex DM Maximum Strength, Giltuss, Mucinex Children's Multi-Symptom Cold, Robitussin Cough & Cold D, Poly Hist DM, Histex-DM, Vicks 44D, Decongestant Cold Formula, Coricidin HBP Day & Night Multi-Symptom Cold, Tylenol Children’s Cold + Flu, Tylenol Cold Multi-Symptom Nighttime, XL-3 Xtra Cold and Cough, Cold Multi-Symptom (Nighttime), Childrens Tylenol Cold Plus Cough, Alka-Seltzer Plus-D Multi-Symptom Sinus & Cold Liquid Gels, Drixoral Cough/Sore Throat, Delsym Night Time Cough & Cold, Tylenol Cold & Cough Nighttime, Tylenol Cold Multi-Symptom Nighttime Liquid, Decorel Forte Plus, Mucinex Sinus-Max Pressure, Pain & Cough, Adult Cold, Flu & Sore Throat, Daytime Cold & Flu, Neocitran Non Drowsy Extra Strength Cold and Flu, Daytime Cold and Flu Relief, Severe Cold Multi-Symptom, Mucinex Nightshift Cold & Flu, Cepacol Extra Strength Sore Throat & Cough, Rynex DM, AccuHist DM Pediatric Drops, Dimetane DX, Brometane DX, Bromphenex DM, Effective Strength Cough Syrup, Carepanto, Rondec-DM, Gencontuss, Giltuss Allergy Plus, Kidcare Cough and Cold, Resperal, Calmylin, Buckleys Mixture, Creomulsion, 12 Hour Cough Relief, Dextromethorphan HBr Adult Formula, Robafen Pediatric Cough & Cold, Mucinex Cough & Chest Congestion, Robichem DM, Broncotron, Delsym Cough+ Chest Congestion DM, Siltussin DM DAS Cough Formula, Tussi-Organidin DM NR, Mucinex Children's Cough, Safetussin DM, Congesta DM, Guaifenesin DM, Vicks DayQuil Cough & Congestion, Guiadrine DM, Diabetic Tussin Cough and Chest Congestion DM, Robitussin Children's Cough & Cold CF, Mucinex Fast-Max Severe Congestion & Cough, Supress-DX, Tussex, Desgen, Trispec PSE, Dimacol, Tusnel-DM Pediatric Drops, Relacon-DM, Tusnel Pediatric, Relacon-DM NR, Despec DM, Trikof-D, Triaminic Day Time Cold & Cough, Promethazine with Dextromethorphan, Tylenol Children’s Cold + Cough + Runny Nose, PediaCare Cough & Runny Nose Plus Acetaminophen, Flu HBP Maximum Strength, Mapap Cough & Sinus Formula, Vicks Formula 44 Custom Care Cough & Cold PM, Flu Relief BP, Tylenol Cold and Flu Severe Day & Night, Dimetapp Children's Multi-Symptom Cold & Flu (old formulation), PediaCare Multi-Symptom Cold Plus Acetaminophen, PediaCare Flu Plus Acetaminophen, Alka-Seltzer Plus Severe Cold & Flu PowerFast Fizz, Alka-Seltzer Plus Maximum Strength Sinus Congestion & Pain PowerFast Fizz, Tylenol Cold Head Congestion Nighttime, Comtrex Cold & Cough Day Night, Theraflu Nighttime Severe Cold & Cough Caplets, Tylenol Cold Head Congestion Day and Night, Comtrex Nighttime Cold & Cough, Alka-Seltzer Plus Maximum Strength Cold & Cough, Multi Symptom Cold (Night Formula), Multi Symptom Cold Relief, Alka-Seltzer Plus Maximum Strength Cold & Cough Liquid Gels, Alka-Seltzer Plus Severe Sinus & Cold Hot Drink Mix, Dimetapp Children's Nighttime Flu, Theraflu Warming Relief Nighttime Multi-Symptom Cold Caplets, Triaminic Multi-Symptom Fever & Cold, Giltuss Multi-Symptom Cold & Flu, Giltuss Children's Multi-Symptom Cold & Flu, Comtrex Cold and Flu Maximum Strength, Comtrex Maximum Strength Cold Relief, Contac Severe Cold and Flu Maximum Stength, Theraflu Flu, Cold and Cough Powder, Comtrex Day and Night, Cough Formula M Multi-Symptom, Comtrex Cold and Flu Maximum Strength Tablet, Comtrex Cold and Flu Maximum Strength Liquid, Genacol Maximum Strength, Contac Cold and Flu Maximum Strength, Co-Apap, Theracaps Multi-Symptom Cough & Cold Reliever, Triaminic Flu, Cough & Fever, Tylenol Children’s Cold + Cough + Sore Throat, PediaCare Cough & Sore Throat Plus Acetaminophen, Triaminic Cough & Sore Throat, Tylenol Cough and Sore Throat Daytime, Triaminic Softchews Cough & Sore Throat, Children's Triacting, Tylenol Cold & Cough Daytime, Topcare Cough and Sore Throat, Vicks DayQuil HBP Cold & Flu, Diabetic Tussin Night Time Cold & Flu, Mucinex Fast-Max Day Time Severe Cold and Night Time Cold & Flu Maximum Strength, Mucinex Fast-Max Day Time Cold & Flu and Night Time Cold & Flu Maximum Strength, Mucinex Fast-Max Day Time Severe Congestion & Cough and Night Time Cold & Flu Maximum Strength, Mucinex Children's Day Time & Night Time Multi-Symptom Cold Value Pack, Respa C&C, Respa C&C IR, Contac Day and Night Cold and Flu, Robitussin Peak Cold Nighttime Cold + Flu, Contac Cold + Flu (Night) Cooling Relief Liquid, Robitussin Cold + Flu (Nighttime), Coricidin HBP Nighttime Multi-Symptom Cold, Vicks Nature Fusion Cold & Flu Nighttime Relief, Multi Symptom NiteTime, Night Time Multi Symptom Cold/Flu Relief, Alka-Seltzer Plus Severe Cold+Cough Night Liquid, Tylenol Cough & Sore Throat Nightime, Clear Cough PM Multi-Symptom, Mucinex Fast-Max Day & Night, Mucinex Sinus-Max Day & Night, DayQuil/NyQuil Severe Cold and Flu, Mucinex Fast-Max Day Severe Cold and Night Cold & Flu, Delsym Night Time Multi-Symptom, Alka-Seltzer Plus Night Cold Formula Liquid, Alka-Seltzer Plus Multi-Symptom Cold & Flu (Night Formula), Alka-Seltzer Plus Severe Sinus Congestion & Cough (Night Formula), Mucinex Fast-Max Night Time Cold & Flu Liquid Gels, Alka-Seltzer Plus Severe Sinus Congestion, Allergy & Cough Liquid Gels, Alka-Seltzer Plus Maximum Strength Night Cold & Flu Liquid Gels, Alka-Seltzer Plus Maximum Strength Day & Night Cold & Flu Liquid Gels (Night Formula), Alka-Seltzer Plus Multi-Symptom Cold & Flu Day & Night Liquid Gels (Night Formula), Alka-Seltzer Plus Night Severe Cold+Flu Hot Drink Mix, All-Nite Cold, Tylenol Severe Cold & Flu Night Time, Multi-Symptom Nighttime, All-Nite Multi-Symptom Cold/Flu Relief, Coricidin HBP Cold Cough and Flu Maximum Strength, Mucinex Sinus-Max Pressure, Pain & Cough and Sinus-Max Clear & Cool Nasal Spray, Mucinex Children's Cold, Cough & Sore Throat, Mucinex Children's Multi-Symptom Cold & Fever, Mucinex Children's FreeFrom Multi-Symptom Cold, Flu & Sore Throat, Delsym Cough+ Cold Day Time, Sudafed PE Head Congestion + Flu Severe, Mucinex Fast-Max Day Time Severe Cold, Non-Pseudo Cold Relief, Tylenol Cold + Mucus Severe, Mucinex Fast-Max Cold, Flu & Sore Throat Liquid Gels, CounterAct Day, Tylenol Cold Head Congestion Severe (old formulation), Mucinex Fast-Max Severe Congestion & Cold, Alka-Seltzer Plus Severe Cough, Mucus & Congestion Liquid Gels, Alka-Seltzer Plus Severe Sinus, Cold & Cough Liquid Gels, Phenflu DM, Alka-Seltzer Plus Severe Cold, Mucus & Congestion, Alka-Seltzer Plus Day Severe Cold+Flu Hot Drink Mix, Rompe Pecho MAX, Cold Head Congestion, Cold Multi-Symptom Severe, ConRx Cold, Robitussin Severe Multi-Symptom Cough Cold + Flu, Mucus Relief Complete, Mucus Relief Plus, Cold & Cough PE Multi-Symptom, Suphedrine PE Cold & Cough, Sudafed PE Pressure+Pain+Cold, Tylenol Cough & Severe Congestion Daytime, Mucinex FreeFrom Cold & Flu Daytime and FreeFrom Cold & Flu Nighttime, Mucinex Fast-Max Severe Congestion & Cough and Nightshift Cold & Flu, Anatuss, Robitussin Cold Cough and Flu, Tylenol Cold Severe Congestion Daytime, Phlemgesic, Balminil Cough and Flu Sugar Free, Theraflu Max-D Severe Cold & Flu, Flutabs, Duraflu, Maxiflu DM, Tusnel-A, Mucinex Fast-Max DM Max and Nightshift Cold & Flu, Mucinex Fast-Max DM Max & Mucinex Nightshift Cold & Flu, Robitussin Peak Cold Daytime Cold + Flu, Contac Complete Cough, Cold & Flu Extra Strength, Tylenol Plus Children's Cold & Cough, Robitussin Cold + Flu (Daytime), Mapap Cold Formula, BC Cough & Cold, Little Colds Multi-Symptom, Vicks Nature Fusion Cold & Flu Multi-Symptom Relief, Theraflu Daytime Severe Cold & Cough, Comtrex Cold and Cough Maximum Strength, Day Relief PE, Vicks Dayquil Cold & Flu Symptom Relief Plus Vitamin C, Day Time Multi-Symptom Cold/Flu Relief, Mucinex Fast-Max Congestion & Headache, Multi Symptom Cold (Day Formula), Alka-Seltzer Plus Severe Sinus Congestion & Cough Liquid Gels, Alka-Seltzer Plus Maximum Strength Day Cold & Flu Liquid Gels, Alka-Seltzer Plus Multi-Symptom Cold & Flu Day Liquid Gels, Theraflu Multi-Symptom Severe Cold with Lipton Flavors, Theraflu Warming Relief Daytime Multi-Symptom Cold Caplets, Theraflu Warming Relief Daytime Severe Cold & Cough, Tylenol Cold Max Day, Tylenol Cold Head Congestion Daytime, Sudafed PE Pressure+Pain+Cough, Flu & Severe Cold & Cough Daytime Powder, Theraflu ExpressMax Daytime Severe Cold & Cough, Mucinex Children's FreeFrom Multi-Symptom Cold & Flu Nighttime, Mucinex Nightshift Sinus, Mucinex Nightshift Cold & Flu Clear & Cool, Mucinex Nightshift Sinus Clear & Cool, Comtrex Non Drowsy Liquigel, Theraflu Flu Cold & Cough, Tylenol Cold + Flu Multi-Action, Alka-Seltzer Plus Flu/Body, Vicks Dayquil Daytime Cold/Flu (old formulation), Comtrex Non-Drowsy, Contac Severe Cold and Flu Non Drowsy, Day Time Multi Symptom, Non-Drowsy Super Strength Contac Complete, Contact Cold and Sore Throat, Day Relief Cold and Flu, Tylenol Cold Non-Drowsy Gelcaps, Daytime Non-Drowsy, Theraflu (pseudoephedrine) Daytime Severe Cold, Daytime Cold, Quelidrine, Alka-Seltzer Plus Flu Formula (old formulation), Alka-Seltzer Plus Cold and Cough Powerfast Fizz, Alka-Seltzer Plus Cold & Cough Formula Effervescent Tablets, Alka-Seltzer Plus Day & Night Cold Formula (Night Cold), Alka-Seltzer Plus Cold Powerfast Fizz Night, Alka-Seltzer Plus Night Cold Formula Effervescent Tablets, Alka-Seltzer Plus Severe Cold Powerfast Fizz Day and Night, Alka-Seltzer Plus Day & Night Cold Formula (Day Cold), Alka-Seltzer Plus Non-Drowsy Cold Effervescent Tablets, Cough-X, Cepacol Dual Relief Sore Throat + Cough Spray, Cepacol Sore Throat + Cough Relief, Spec-T Sore Throat/Cough Suppressant, Cough-X Cough Relief, Chloraseptic Total Sore Throat+Cough Lozenges, Cepastat Sore Throat & Cough, AccuHist PDX Syrup, Uni-Hist PDX Syrup, Allanhist PDX Syrup, EndaCof-PD, Bromhist-PDX, Acutuss DM Pediatric, Uni-Hist DM Pediatric Syrup, AccuHist DM Pediatric Syrup, Bromhist-DM, Pediahist DM Syrup, Histacol DM Pediatric Syrup, Niva-Hist DM, Alahist DM (old formulation), BroveX PB DM, BPM DM PHEN, Duravent DPB, Alacol DM, BP Allergy DM, Presgen B, Y-COF DMX, TL-Hist DM, Tusdec-DM, Bromtuss DM, Dur-Tann DM, Dimaphen DM, Tussi-Pres B, BroveX PEB DM, BPM PE DM, LoHist PEB DM, Dimetapp Children's Multi-Symptom Cold Relief Dye-Free, Balacall DM, Brotapp PE-DM, Lohist-DM, Glenmax PEB DM, Bromatan-DM, Glenmax PEB DM Forte, DuraTan DM, EndaCof-DM, AP-Hist DM, M-Hist DM, Relcof DM, Histinex DM, Prohistine DM, Poly DM, Highland DM, Delhistine DM, Polytine DM, Iohist DM, KG Hist DM, Uni Multihist DM, Liquihistine DM, Trihist DM, Poly Histine DM, DM Cold and Cough, Durahistine DM, Dimetapp DM, EndaCof PD Drops, PediaHist DM, BroveX PSE DM Tablets, BroveX PSE DM, PBM Allergy, BroveX PSB DM, Anaplex DMX, BromTann/DM Tann/PSE Tann, Bromdex D, Neo DM Syrup, Dallergy DM, Myphetane DX, Bromanate DX Cough, Bromatane DX, Myphetane DX Cough, Bromophed-DX, Liquiphed DM, Bromadine-DM, Anaplex DM, Brotapp-DM, Andehist DM NR Syrup, Bromtapp-DM, Bromaxefed DM RF Syrup, PSE Brom DM, Bromaline DM, Carbofed DM Syrup, Uni-Hist DM Pediatric Drops, Bromplex DM, Bromhist-DM Drops, Pediahist DM Drops, Q-Tapp DM, Bromph DM, Uni-Hist PDX Drops, Robitussin Allergy & Cough, Allanhist PDX Drops, Histacol BD Drops, Brom Tann, ProHist DM, P-Hist DM Drops, Carbodex DM Syrup, Sildec DM, DMax, TriTuss-A Drops, Dacex-A, XiraHistDM, X-Hist DM, DMax Pediatric Drops, DMax Syrup, DMax Pediatric, Trituss-A, Andehist DM NR, Carbodex DM Drops, Cordron-DM, Dynatuss, Tussafed, Biodec DM, Rondamine DM, Maldec-DM, Cydec-DM Syrup, Dura-Ron DM, Cydec-DM Drops, Carbaxef-DM, Carbofed DM Drops, Decahist-DM, Pediatex-DM, Cordron-DM NR, Pseudo Carb DM, Mintex DM, PSE Carbinoxamine DM, PSE Carb DM Drops, Carboxine DM, Carboxine 12 DM, Carb PSE 12 DM, PSE Allergy DM, Cordron-12 DM, Pediatex 12 DM, QC Cough/Cold, Primatuss 4, Tricodene Sugar Free, Triaminic Softchews Cough & Runny Nose, Dimetapp Children's Long Acting Cough Plus Cold, Robitussin Children's Cough & Cold Long-Acting, Robitussin Cough & Cold Long-Acting, Triaminic Night Time Cough & Runny Nose, Scot-Tussin DM, St. Joseph HBP Cough & Cold, Robitussin Children's Nighttime Cough Long-Acting DM, SymPak DM, Broncopectol, ChlorDex GP, Qual-Tussin, Quartuss, Genelan NF, Zotex-DM, Neotuss D, Extendryl DM, Donatussin DM, Ceron-DM Drops, Ceron-DM, Rondex-DM, Rondex-DM Drops, Dec-Chlorphen DM, Dec-Chlorphen DM Drops, HistadecDM, CP Dec DM, Neo DM Drops, Nasohist-DM Pediatric, Cardec DM Drops, Balamine DM, Reme Tussin DM, Tussplex DM, Norel CS, Cardec DM, C-Phen DM, C-Phen DM Drops, Sildec-PE DM Drops, Sildec-PE DM, DCP Drops, EndaCof Drops, PE-Hist DM, Maxichlor PEH DM, ED DM, Poly-Tussin DM, Ricotuss, Tri-Dex PE, Z-Dex 12 D, Trigofen DM Drops, Virdec DM, Zoden DM Drops, Phenabid DM, Re DCP, Sonahist-DM, RE DCP Drops, Nohist-DMX, Bronkids, Nasohist-DM, DM-PE-Chlor, CP Dec-DM Drops, PD-Cof Drops, PD-Cof, Zotex-12D, Quartuss DM, Statuss DM, NoHist-PDX, Relahist-DM, Albatussin SR, Cerose DM, Maxiphen ADT, Tussar DM, Liquituss R-DM, Centergy DM, Atuss DM, Father John's Medicine Plus, Norel DM, NeoTuss Plus, De-Chlor DM, De-Chlor DR, Coldtuss-DR, Tri-Vent DPC, Giltuss Allergy Plus Cough & Congestion, Atuss DR, Giltuss Children's Allergy Plus Cough & Congestion, Corfen-DM, Uni-Tuss DM, Mintuss DR, Trital DM, Ed A-Hist DM, P Chlor DM, Dex PC, Tricodene Forte, Tricodene NN, Cheracol Plus, Therahist, Kophane, Threamine DM, Rhinosyn-DM, Vicks 44M Pediatric, Creomulsion Cough/Cold/Allergy, Creomulsion Pediatric, Children's Nyquil, Rescon-DM, Tanafed-DM, C-Phed DM, M-End DM, Atuss-12 DM, Dicel DM, Atuss DS, Entre-S, Maxichlor PSE DM, Kidkare Cough/Cold, Neutrahist PDX Drops, AccuHist PDX Drops, CPM-PSE DM Drops, Esocor P, Mesehist DM, Triaminic-D Multi-Symptom Cold, Allres DS, Duotan DM, T-Tanna DM, Pedia Relief Cough-Cold, Deka, Dexall, Alahist DM, Bionatuss DXP, Panatuss Pediatric DXP, G-P-Tuss DXP, Y-Cof DM, Supress A, Panatuss DXP, Tussall, Tussall-ER, Supress A Pediatric, Poly Tan DM, M-End DMX, Donatussin DM Suspension, WesTussin DM, Coryza-DM, ProHist, P-Hist, Tannate DMP-DEX, C-Phed DPD Tann, DuraTan Forte, Bromatan Plus, Dur-Tann Forte, TanDur DM, SuTan-DM, Tannate PD-DM, Deltuss DMX, TanaCof DM, Babee Cof, Silphen DM, Vicks Formula 44 Custom Care Dry Cough Suppressant, Balminil DM, Benylin DM, Novahistine DM, Covonia Bronchial Balsam, Triaminic Thin Strips Long Acting Cough, Benadryl for the Family Dry Forte, Theraflu Thin Strips Cough, Neocitran Thin Strips Cough, Contac Cough, Robafen Cough Liquidgels, Jack & Jill Thin Strips Cough, Tussinol for Dry Coughs, Bisolvon Dry Junior, Dristan DM, Dexi-Tuss, Nucosef DM, Strepsils Cough Relief, Delsym Children's 12-Hour Cough Relief, Sucrets Cough, Pedia Relief, Triaminic Long Acting Cough, Creomulsion Children, Buckley's DM, Robitussin Direct Cough, Tussin Cough Gels (Long Acting), Vicks Nature Fusion Cough, Duract Max Strength Cough, Lloydspharmacy Dry Adult Cough, Hold, Triaminic Thin Strips Cough, Robitussin 12-Hour Cough Relief, Giltuss Honey DM 8hr Cough, Vicks Formula 44, Giltuss Children's Honey DM 8hr Cough, ElixSure Cough, Scot-Tussin DM Cough Chasers, Hold DM, Pertussin CS Childrens, Robitussin Children's Cough Long-Acting, St. Joseph Cough Suppressant, Pertussin ES, PediaCare Children's Long-Acting Cough, Tussin Pediatric, Vicks Dayquil Cough, Dytan-DM, Duratuss AC 12, D-Tann DM, Nighttime Cough, Safetussin PM, Robitussin Nighttime Cough DM Maximum Strength, Vicks Nyquil Cough DM + Congestion, Lortuss DM, Mastussin DM, Recofen D, Recofen Plus, Ri-Tussin DM, T-Tussin DM, Tusscidin DM, Bidex-DMI, Vicks DayQuil Mucus Control DM, Humibid CS, GG-DM SR, Humigen DM, Tussidin DM, Altarussin DM, Guiat Clear DM, Cough Formula-DM, Guaiasorb Cough Medicine, Kita La Tos, Q-Tussin DM, Bidex-DM, Nalspan Senior DX, Diabetic Tuss DM, Vicks Formula 44 Custom Care Chesty Cough, Scot-Tussin Senior, Mucinex Fast-Max DM Max, Safetussin 30 DM, Pecgen DMX, Duratuss DM, Guiatuss Clear, Iophen DM NR, Allfen DM, PediaCare Cough & Congestion, Mucinex Children's FreeFrom Cough & Mucus, S-Pack DM, HT Tuss DM, Monafed DM, Hydro-Tuss DM, Alka-Seltzer Plus Maximum Strength Cough & Chest Congestion PowerFast Fizz, Drituss DM, Guaifen DM, Maxi-Tuss DM, Rompe Pecho DM, Su-Tuss DM, Biospec DMX, Muco-Fen 800 DM, Delsym Children’s Cough+ Chest Congestion DM, Guai-Dex, Guaifenesin DM SR, Tussi-Bid, Sudal DM, Iophen DM, Ru-Tuss 800 DM, Mintab DM, Bidex-A, Mindal DM, Robitussin Children' s Cough & Chest Congestion DM, Z-Cof LA, Extuss LA, ExeFen-DM, Siltussin DM, Simuc-DM, Phlemex, DuraDEX, Relacon LAX, Aquatab DM, Z-Cof LAX, Cheracol D Cough, Robafen DM Clear, DuraDEX Forte, Zotex DMX, Tussi-Organidin DM-S NR, Robitussin Cough + Chest Congestion Sugar-Free DM, Guaifen DM NR, Guiadrine DX, Balminil DM + Expectorant Sugar Free, Biocotron, Vicks Nature Fusion Cough & Chest Congestion, Tussin Cough, G Bid DM, Atuss-12 DX, Cheracol-D, G-Tron, G-Zyncof, Robafen DM Max, Guaibid DM, Robitussin Cough + Chest Congestion DM Maximum Strength, Cofex-DM, Tussin DM Clear, Mucosa DM, Alka-Seltzer Plus Maximum Strength Cough & Mucus DM, TabTussin DM, Siltussin-DM DAS-NA, Siltussin-DM DAS-NA Maximum Strength, Duratuss DM 12, Refenesen Chest Congestion Relief DM, Brontuss, Guaifenex DM, Coricidin HBP Multi-Symptom Cold (Day), Triaminic Cough & Congestion, Dex-Tuss DM, Fenesin DM IR, Tussin DM Max, Mucus Relief Cough, Gani-Tuss-DM NR, Muco-Fen DM, Fenex-DM, Iobid DM, Q-Bid DM, Touro DM, Respa-DM, Mucobid DM, Fenesin DM, Humibid DM Pediatric, Iofen-DM NF, Ambi 1000/55, Phanatuss, Giltuss Honey Cough & Chest Congestion, Naldecon Senior DX, Giltuss HBP Cough & Chest Congestion, Guiatussin-DM, Giltuss Diabetic Cough & Cold, Halotussin DM, Giltuss Children's Honey Cough & Chest Congestion, Guiatuss DM, Double-Tussin DM, Giltuss Children's Cough & Chest Congestion, Halotussin DM Sugar Free, Rhinosyn-DMX, Tuss-DM, Kolephrin GG/DM, Amibid DM, Duraganidin, Genatuss DM, Glycotuss-DM, Mytussin DM, Tolu-Sed DM, Vicks Pediatric Formula 44e Cough & Chest Congestion Relief, Guiacough DM, Lotussin DM, Anti-Tuss DM, Aquabid DM, GG/DM, Mucinex Children's Congestion & Cough, Mucinex Children's FreeFrom Multi-Symptom Cold & Stuffy Nose, Broncotron Ped, Rompe Pecho CF, Tusso-DMR, Pres Gen Pediatric, Duraphen DM, Sinutuss DM, Nortuss-DE, G-Tusicof, Zotex Pediatric, Tussidex, Zotex, Relhist DMX, Broncotron-D, G-Supress DX, Tussi-Pres, G-Tron Ped, Tussi-Pres Pediatric, Giltuss Pediatrics, Tussafed-EX, GDP-EX, TriTuss, TriTuss-ER, Tussafed-EX Drops, Certuss-D (old formulation), Dynatuss EX, Dacex-PE, Anextuss, Dexcon-PE, Zotex LAX, Dacex-DM, Duraphen II DM, Maxiphen DM, G-Phen DM, Despec DM Syrup, Phlemex Forte, Phlemex-PE, Guaphen Forte, Guaphen II DM, Endacon, Z-Dex, Robafen CF, DuraMAX, Tusso-XR, Execof ER, Tusso-DM, Ambi 40/1000/60, Maxiphen-G DM, Z-tuss DM, Deconex DM, PDM GG, ExeTuss-DM, VanaTab DM, Despec NR Drops, Endacon DM, Giltuss TR, Q-Tussin CF, Tussin CF, Desgen DM, Tusslin, Robitussin Multi-Symptom Cold CF, Robitussin Multi-Symptom Cold CF Maximum Strength, Mucinex Fast-Max Day Time Severe Congestion & Cough, Mucinex Children's Day Time Multi-Symptom Cold, Giltuss Cough & Cold, Giltuss Children's Cough & Cold, Duravent DM, Zotex-EX, Nivanex DMX, Naldecon-DX Adult, Guiatuss CF, Guiatussin-CF, Naldelate DX Childrens, Naldecon-DX Pediatric, Naldelate DX Pediatric, Nalphen DX Childrens, Nalphen DX Pediatric, Ipsatol Cough Formula, Naldecon-DX Childrens, Uni Tussin CF, Pediacon DX, Phenadex, Tri-Dec, Humibid DM, Z-Cof 8DM, Entex Pac, Entre-Cough, Poly-Vent DM, Medent-DMI, Robitussin CF, Mardrops-DX, Maxifed DM, Sudafed Cough, Sudafed Cough Syrup, Balminil DM + Decongestant + Expectorant, TL-Dex DM, Ambi 600/1000/30, Benylin DM-D-E, Ambi 80/780/40, Calmylin 4, Ambi 60/580/30, Ambifed DM, Tenar DM, Novahistine DM Expectorant with Decongestant, Z-COF 12, Donatussin DM Syrup, Anatuss DM, Ambenyl-D, Novahistine DMX, Ru-Tuss Expectorant, Rhinosyn-X, Dorcol Childrens Cough, Syn-Rx DM, Guaifenex DM RX, Suda-Tussin DM, Pseudogest-DM, Tusnel Ped-C, Medent DM, Daytime Liquicap, Multi Symptom Cough and Cold, Tussin Cough and Cold, Protuss DM, Med-RX DM, Tussafed-LA, Touro CC, Profen Forte DM, Profen II DM, ExeFen-DMX, Profen II DM Liquid, ExeClear-DM, S-Pak DM, Ru-Tuss DM, Aldex GS DM, Coldmist DM, Altarussin CF, Z-Cof DM(obs), Ambifed-G DM, Touro CC-LD, Despec Drops, Pseudo Cough, Relasin DM, Z-Cof DM, Ambi 40 /400 /20, Liquicough DM, Maxifed DMX, Z-Cof 12DM, Pseudo DM GG, Pseudo Max DMX, SudaTex-DM, Desgen DM (with pseudoephedrine), P-Tuss DM, Mucinex Instasoothe Sore Throat + Cough Relief, Delsym Cough+ Soothing Action, Robitussin Medi-Soothers Cough DM, Hot Lemon Cough and Colds Relief DM, Theraflu Cold & Cough, PediaCare Daytime Multi-Symptom Cold, Sudafed PE Children's Cold & Cough, Albatussin Pediatric, Albatussin Pediatric Drops, Little Colds Decongestant/Cough, Children's Triacting Daytime, Safetussin CD, Triaminic Thin Strips Day Time Cold & Cough, PediaCare Children's Multi-Symptom Cold, Theraflu Thin Strips Daytime Cold and Cough, Vicks Formula 44 Custom Care Congestion, Dimetapp Toddler's Drops Decongestant Plus Cough, 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Dextromethorphan Levels and Effects while Breastfeeding
Summary of Use during Lactation
The amounts of dextromethorphan and its active metabolite in breastmilk are very low and are not expected to affect the nursing infant. It is best to avoid the use of products with a high alcohol content while nursing.
Drug Levels
Dextromethorphan is metabolized to its active metabolite of dextrorphan by CYP2D6. Dextrorphan is further metabolized to dextrorphan glucuronide by UGT2B.
Maternal Levels. Twenty nursing mothers who were extensive metabolizers of CYP2D6 donated a blood sample and completely emptied one breast 2 hours after a single oral dose of dextromethorphan 30 mg. All mothers were at least 3 months postpartum and subjects who were poor, intermediate, or ultra-rapid metabolizers were excluded from the study. The average milk concentration of dextromethorphan at the presumed peak of 2 hours after the dose was 2.5 mcg/L (95% CI 1.5 to 3.9 mg/L). The average milk concentration of the active metabolite dextrorphan at that time was 14 mcg/L (95% CI 10.7 to 17.9 mg/L). These values translated to average “worst-case” daily infant dosages of 0.33 mcg/kg and 1.8 mcg/kg, and relative infant dosages of 0.07% and 0.41% for dextromethorphan and dextrorphan, respectively. The authors used published values of serum concentrations after a typical 60 mg twice daily dosage regimen to estimate average steady-state relative infant dosages of 0.04% and 0.07% for dextromethorphan and dextrorphan, respectively.[1] The potential contribution of dextrorphan glucuronide to infant dosage in neonates, who can deconjugate glucuronides some compounds, was not estimated.
Eight women who were given dextromethorphan (dose not specified) following a full-term cesarean section delivery provided milk samples at 4 to 6 hours after their third dose. The authors calculated median estimated relative infant doses to be 0.239% for dextromethorphan and 0.288% for its major active metabolite, dextrorphan.[2]
Infant Levels. Blood samples were obtained at an unspecified time from 8 breastfed infants whose mothers were given dextromethorphan (dose not specified) following a full-term cesarean section delivery. Only one of the 8 infants had a detectable plasma concentration of dextromethorphan. This infant’s mother had a much higher milk level of dextromethorphan than the other 7 women.[2]
Effects in Breastfed Infants
Relevant published information was not found as of the revision date.
Effects on Lactation and Breastmilk
Relevant published information was not found as of the revision date.
References
- 1.
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Shum S, Yadav A, Fay E, et al. Infant dextromethorphan and dextrorphan exposure via breast milk from mothers who are CYP2D6 extensive metabolizers. J Clin Pharmacol. 2022;62:747–55. [PMC free article: PMC9153952] [PubMed: 34889461]
- 2.
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Lieberman D, O'Brien D, Meyers R, et al. Assessment of dextromethorphan concentration in human breast milk. Am J Obstet Gynecol. 2023;228(1) Suppl:S119. [Abstract]
Substance Identification
Substance Name
Dextromethorphan
CAS Registry Number
125-71-3
Drug Class
Breast Feeding
Lactation
Milk, Human
Antitussive Agents
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