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Dextromethorphan use while Breastfeeding

Medically reviewed by Drugs.com. Last updated on Jun 29, 2022.

Drugs containing Dextromethorphan: Mucinex DM, Promethazine DM, Bromfed DM, Delsym, Vicks DayQuil Severe Cold & Flu, Robitussin Cough + Chest Congestion DM, Vicks NyQuil Cold & Flu Nighttime Relief, Nuedexta, Vicks Dayquil Cold & Flu Relief, Vicks NyQuil Severe Cold & Flu, Show all 1016 »Tussin DM, Cough & Cold Relief, Dimetapp Children's Cold & Cough, Vicks Nyquil Cough, Delsym 12 Hour Cough Relief, Theraflu Flu & Cough, Tylenol Cold & Flu Severe, Mucinex Fast-Max Severe Congestion & Cough, Robitussin Cough & Cold D, Coricidin HBP Cough & Cold, Capmist DM, Mucinex Fast-Max Severe Cold, Bisolvon Dry, Dry Cough, Tusnel, Siltussin DM, Codral Cold and Flu + Cough Day and Night, Giltuss, Resperal-DM, Dextromethorphan HBr Adult Formula, Robitussin Nighttime Cough DM, Coricidin HBP Chest Congestion & Cough, Mucinex DM Maximum Strength, Mucinex Nightshift Cold & Flu, Mucus Relief DM, Sudafed PE Cold & Cough, Adult Cold, Flu & Sore Throat, Comtrex Cold & Cough, Robitussin Cough & Allergy, Polytussin DM, Robafen DM, Delsym Cough+ Chest Congestion DM, Mucinex Children's Cough, Guaifenesin DM, Coricidin HBP Maximum Strength Flu, Childrens Tylenol Cold Plus Cough, Mucinex Fast-Max Cold, Flu & Sore Throat, Daytime Cold & Flu, Rynex DM, Vicks Children’s NyQuil Cold & Cough, Panatuss DXP, Cough Syrup DM, DexAlone, PediaCare Children's Long-Acting Cough, Vicks Dayquil Cough, Cough Formula-DM, Diabetic Tuss DM, Tussin Cough, Zyncof, Benylin Expectorant, Deconex DMX, Dexcon-DM, Mucinex Children's Multi-Symptom Cold, Capron DMT, Triaminic Multi-Symptom Fever, Coricidin HBP Day & Night Multi-Symptom Cold, XL-3 Xtra Cold and Cough, Alka-Seltzer Plus-D Multi-Symptom Sinus & Cold Liquid Gels, Coricidin HBP Nighttime Multi-Symptom Cold, Alka-Seltzer Plus Severe Sinus Congestion, Allergy & Cough Liquid Gels, Vicks Nyquil D Cold and Flu Nighttime Relief, Mucinex Children's Cold, Cough & Sore Throat, Mucinex Sinus-Max Pressure, Pain & Cough, Theraflu Daytime Severe Cold & Cough, Vicks Dayquil Daytime Cold/Flu (old formulation), Daytime Cold and Flu Relief, EndaCof-DM, Bromophed-DX, Bromadine-DM, PSE Brom DM, Maxiphen ADT, Giltuss Allergy Plus Cough & Congestion, Corfen-DM, Children's Nyquil, CPM-PSE DM Drops, Alahist CF, Benylin DM, Calmylin, Phlemex, Guiatuss DM, Broncotron Ped, Tussi-Pres, VanaTab DM, Giltuss TR, Tussin CF, Benylin DM-D-E, Despec DM, Theraflu Cold & Cough, Promethazine with Dextromethorphan, Vicks NyQuil Cold & Flu Nighttime Relief (Alcohol Free), Tylenol Cold Multi-Symptom Nighttime, Alka-Seltzer Plus Maximum Strength Cold & Cough, Triaminic Softchews Cough & Sore Throat, Diabetic Tussin Night Time Formula, Tylenol Cold & Cough Nighttime, Night Time Cold & Flu, Vicks NyQuil HBP Cold & Flu, Mucinex Fast-Max Cold, Flu & Sore Throat Liquid Gels, Robitussin Severe Multi-Symptom Cough Cold + Flu, Robitussin Cold Cough and Flu, Tylenol Cold Severe Congestion Daytime, Flutabs, Duraflu, Neocitran Non Drowsy Extra Strength Cold and Flu, Day Time Multi-Symptom Cold/Flu Relief, Theraflu Multi-Symptom Severe Cold with Lipton Flavors, Theraflu Warming Relief Daytime Severe Cold & Cough, Theraflu ExpressMax Daytime Severe Cold & Cough, Mucinex Nightshift Severe Cold and Flu, Mucinex Nightshift Sinus Clear & Cool, Bromhist-PDX, Dimaphen DM, Cold & Cough Childrens, DM Cold and Cough, Carbofed DM Syrup, Dynatuss, Effective Strength Cough Syrup, Robitussin Children's Cough & Cold Long-Acting, Qual-Tussin, Rondec-DM, Ed A-Hist DM, Alahist DM, M-End DMX, Bromatan Plus, Deltuss DMX, Abatuss DMX, Strepsils Cough, Bisolvon Dry Junior, Delsym Children's 12-Hour Cough Relief, Robitussin CoughGels Long-Acting, Altarussin DM, Pecgen DMX, Iophen DM, G-Tron, Creo-Terpin, Vicks DayQuil Cough & Congestion, Fenex-DM, Giltuss Children's Cough & Chest Congestion, Pres Gen Pediatric, Tussidex, Zotex, Broncotron-D, G-Supress DX, Tusicof, Phlemex Forte, Phlemex-PE, Guaphen II DM, Robitussin CF, Triaminic Day Time Cold & Cough, Codimal DM, Prolex DM, Decongestant Cold Formula, Capron DM, Tylenol Children’s Cold + Cough + Runny Nose, PediaCare Cough & Runny Nose Plus Acetaminophen, Flu HBP Maximum Strength, Mapap Cough & Sinus Formula, Vicks Formula 44 Custom Care Cough & Cold PM, Flu Relief BP, Coricidin HBP Multi-Symptom Cold (Night), Tylenol Cold and Flu Severe Day & Night, Dimetapp Children's Multi-Symptom Cold & Flu (old formulation), Tylenol Children’s Cold + Flu, PediaCare Multi-Symptom Cold Plus Acetaminophen, PediaCare Flu Plus Acetaminophen, Tylenol Cold Head Congestion Nighttime, Comtrex Cold & Cough Day Night, Theraflu Nighttime Severe Cold & Cough Caplets, Tylenol Cold Head Congestion Day and Night, Comtrex Nighttime Cold & Cough, Cold Multi-Symptom (Nighttime), Multi Symptom Cold (Night Formula), Multi Symptom Cold Relief, Alka-Seltzer Plus Maximum Strength Cold & Cough Liquid Gels, Alka-Seltzer Plus Severe Cold & Flu Formula Effervescent Tablets, Alka-Seltzer Plus Severe Sinus & Cold Hot Drink Mix, Dimetapp Children's Nighttime Flu, Theraflu Warming Relief Nighttime Multi-Symptom Cold Caplets, Triaminic Multi-Symptom Fever & Cold, Giltuss Multi-Symptom Cold & Flu, Giltuss Children's Multi-Symptom Cold & Flu, Comtrex Cold and Flu Maximum Strength, Comtrex Maximum Strength Cold Relief, Contac Severe Cold and Flu Maximum Stength, Theraflu Flu, Cold and Cough Powder, Comtrex Day and Night, Cough Formula M Multi-Symptom, Comtrex Cold and Flu Maximum Strength Tablet, Comtrex Cold and Flu Maximum Strength Liquid, Genacol Maximum Strength, Contac Cold and Flu Maximum Strength, Tylenol Cold, Allpanto-S, Co-Apap, Theracaps Multi-Symptom Cough & Cold Reliever, Triaminic Flu, Cough & Fever, Delsym Cough & Sore Throat, Tylenol Children’s Cold + Cough + Sore Throat, PediaCare Cough & Sore Throat Plus Acetaminophen, Triaminic Cough & Sore Throat, Drixoral Cough/Sore Throat, Tylenol Cough and Sore Throat Daytime, Children's Triacting, Tylenol Cold & Cough Daytime, Topcare Cough and Sore Throat, Vicks DayQuil HBP Cold & Flu, Diabetic Tussin Night Time Cold & Flu, Mucinex Fast-Max Day Time Severe Cold and Night Time Cold & Flu Maximum Strength, Mucinex Fast-Max Day Time Cold & Flu and Night Time Cold & Flu Maximum Strength, Mucinex Fast-Max Day Time Severe Congestion & Cough and Night Time Cold & Flu Maximum Strength, Mucinex Children's Day Time & Night Time Multi-Symptom Cold Value Pack, Respa C&C, Respa C&C IR, Contac Day and Night Cold and Flu, Robitussin Peak Cold Nighttime Cold + Flu, Contac Cold + Flu (Night) Cooling Relief Liquid, Delsym Night Time Cough & Cold, Robitussin Cold + Flu (Nighttime), Vicks Nature Fusion Cold & Flu Nighttime Relief, Multi Symptom NiteTime, Night Time Multi Symptom Cold/Flu Relief, Alka-Seltzer Plus Severe Cold+Cough Night Liquid, Tylenol Cough & Sore Throat Nightime, Clear Cough PM Multi-Symptom, Mucinex Fast-Max Day & Night, Mucinex Sinus-Max Day & Night, Mucinex Fast-Max Day Severe Cold and Night Cold & Flu, Delsym Night Time Multi-Symptom, Tylenol Cold Multi-Symptom Nighttime Liquid, Alka-Seltzer Plus Night Cold Formula Liquid, Alka-Seltzer Plus Multi-Symptom Cold & Flu (Night Formula), Alka-Seltzer Plus Severe Sinus Congestion & Cough (Night Formula), Mucinex Fast-Max Night Time Cold & Flu Liquid Gels, Alka-Seltzer Plus Maximum Strength Night Cold & Flu Liquid Gels, Alka-Seltzer Plus Maximum Strength Day & Night Cold & Flu Liquid Gels (Night Formula), Alka-Seltzer Plus Multi-Symptom Cold & Flu Day & Night Liquid Gels (Night Formula), Alka-Seltzer Plus Night Severe Cold+Flu Hot Drink Mix, All-Nite Cold, Tylenol Severe Cold & Flu Night Time, Multi-Symptom Nighttime, NyCair, All-Nite Multi-Symptom Cold/Flu Relief, Coricidin HBP Cold Cough and Flu Maximum Strength, Mucinex Sinus-Max Pressure, Pain & Cough and Sinus-Max Clear & Cool Nasal Spray, Mucinex Children's Multi-Symptom Cold & Fever, Mucinex Children's FreeFrom Multi-Symptom Cold, Flu & Sore Throat, Delsym Cough+ Cold Day Time, Sudafed PE Head Congestion + Flu Severe, Mucinex Fast-Max Day Time Severe Cold, Tylenol Cold Multi-Symptom Severe, Non-Pseudo Cold Relief, Tylenol Cold + Mucus Severe, CounterAct Day, Tylenol Cold Head Congestion Severe (old formulation), Mucinex Fast-Max Severe Congestion & Cold, Decorel Forte Plus, Alka-Seltzer Plus Severe Cough, Mucus & Congestion Liquid Gels, Alka-Seltzer Plus Severe Sinus, Cold & Cough Liquid Gels, Phenflu DM, Alka-Seltzer Plus Severe Cold, Mucus & Congestion, Alka-Seltzer Plus Day Severe Cold+Flu Hot Drink Mix, Rompe Pecho MAX, Cold Head Congestion, Cold Multi-Symptom Severe, ConRx Cold, Mucus Relief Complete, Mucus Relief Plus, Cold & Cough PE Multi-Symptom, Suphedrine PE Cold & Cough, Sudafed PE Pressure+Pain+Cold, Tylenol Cough & Severe Congestion Daytime, Mucinex FreeFrom Cold & Flu Daytime and FreeFrom Cold & Flu Nighttime, Mucinex Fast-Max Severe Congestion & Cough and Nightshift Cold & Flu, Anatuss, Phlemgesic, Balminil Cough and Flu Sugar Free, Theraflu Max-D Severe Cold & Flu, Maxiflu DM, Tusnel-A, Mucinex Fast-Max DM Max and Nightshift Cold & Flu, Mucinex Fast-Max DM Max & Mucinex Nightshift Cold & Flu, Robitussin Peak Cold Daytime Cold + Flu, Contac Complete Cough, Cold & Flu Extra Strength, Tylenol Plus Children's Cold & Cough, Robitussin Cold + Flu (Daytime), Mapap Cold Formula, BC Cough & Cold, Little Colds Multi-Symptom, Vicks Nature Fusion Cold & Flu Multi-Symptom Relief, Comtrex Cold and Cough Maximum Strength, Day Relief PE, Vicks Dayquil Cold & Flu Symptom Relief Plus Vitamin C, Mucinex Fast-Max Congestion & Headache, Multi Symptom Cold (Day Formula), Alka-Seltzer Plus Severe Sinus Congestion & Cough Liquid Gels, Alka-Seltzer Plus Maximum Strength Day Cold & Flu Liquid Gels, Alka-Seltzer Plus Multi-Symptom Cold & Flu Day Liquid Gels, Cold Multi-Symptom (Daytime), Theraflu Warming Relief Daytime Multi-Symptom Cold Caplets, Tylenol Cold Max Day, Tylenol Cold Head Congestion Daytime, Sudafed PE Pressure+Pain+Cough, Flu & Severe Cold & Cough Daytime Powder, Mucinex Children's FreeFrom Multi-Symptom Cold & Flu Nighttime, Mucinex Nightshift Sinus, Mucinex Nightshift Cold & Flu Clear & Cool, Comtrex Non Drowsy Liquigel, Theraflu Flu Cold & Cough, Tylenol Cold + Flu Multi-Action, Alka-Seltzer Plus Flu/Body, Comtrex Non-Drowsy, Contac Severe Cold and Flu Non Drowsy, Day Time Multi Symptom, Non-Drowsy Super Strength Contac Complete, Contact Cold and Sore Throat, Day Relief Cold and Flu, Tylenol Cold Non-Drowsy Gelcaps, Daytime Non-Drowsy, Theraflu (pseudoephedrine) Daytime Severe Cold, Severe Cold Multi-Symptom, Daytime Cold, Quelidrine, Alka-Seltzer Plus Flu Formula (old formulation), Alka-Seltzer Plus Cold & Cough Formula Effervescent Tablets, Alka-Seltzer Plus Day & Night Cold Formula (Night Cold), Alka-Seltzer Plus Night Cold Formula Effervescent Tablets, Alka-Seltzer Plus Day & Night Cold Formula (Day Cold), Alka-Seltzer Plus Non-Drowsy Cold Effervescent Tablets, Cepacol Extra Strength Sore Throat & Cough, Cough-X, Cepacol Dual Relief Sore Throat + Cough Spray, Cepacol Sore Throat + Cough Relief, Spec-T Sore Throat/Cough Suppressant, Cough-X Cough Relief, Chloraseptic Total Sore Throat+Cough Lozenges, Cepastat Sore Throat & Cough, AccuHist PDX Syrup, Uni-Hist PDX Syrup, Allanhist PDX Syrup, EndaCof-PD, Acutuss DM Pediatric, Uni-Hist DM Pediatric Syrup, AccuHist DM Pediatric Syrup, Bromhist-DM, Pediahist DM Syrup, Histacol DM Pediatric Syrup, Niva-Hist DM, Alahist DM (old formulation), BroveX PB DM, BPM DM PHEN, Duravent DPB, Alacol DM, BP Allergy DM, Presgen B, Y-COF DMX, TL-Hist DM, Tusdec-DM, Bromtuss DM, Dur-Tann DM, Tussi-Pres B, BroveX PEB DM, BPM PE DM, LoHist PEB DM, Dimetapp Children's Multi-Symptom Cold Relief Dye-Free, Balacall DM, Brotapp PE-DM, Lohist-DM, Glenmax PEB DM, Bromatan-DM, Glenmax PEB DM Forte, DuraTan DM, AP-Hist DM, M-Hist DM, Relcof DM, Histinex DM, Prohistine DM, Poly DM, Highland DM, Delhistine DM, Polytine DM, Iohist DM, KG Hist DM, Uni Multihist DM, Liquihistine DM, Trihist DM, Poly Histine DM, Durahistine DM, Dimetapp DM, EndaCof PD Drops, AccuHist DM Pediatric Drops, PediaHist DM, BroveX PSE DM Tablets, BroveX PSE DM, PBM Allergy, BroveX PSB DM, Anaplex DMX, BromTann/DM Tann/PSE Tann, Bromdex D, Neo DM Syrup, Dallergy DM, Dimetane DX, Myphetane DX, Bromanate DX Cough, Bromatane DX, Myphetane DX Cough, Liquiphed DM, Brometane DX, Anaplex DM, Bromphenex DM, Brotapp-DM, Andehist DM NR Syrup, Bromtapp-DM, Bromaxefed DM RF Syrup, Bromaline DM, Uni-Hist DM Pediatric Drops, Bromplex DM, Bromhist-DM Drops, Pediahist DM Drops, Q-Tapp DM, Bromph DM, Uni-Hist PDX Drops, Robitussin Allergy & Cough, Allanhist PDX Drops, Histacol BD Drops, Brom Tann, ProHist DM, P-Hist DM Drops, Carbodex DM Syrup, Sildec DM, DMax, TriTuss-A Drops, Dacex-A, XiraHistDM, X-Hist DM, DMax Pediatric Drops, DMax Syrup, DMax Pediatric, Trituss-A, Andehist DM NR, Carbodex DM Drops, Cordron-DM, Tussafed, Biodec DM, Rondamine DM, Maldec-DM, Cydec-DM Syrup, Dura-Ron DM, Cydec-DM Drops, Carbaxef-DM, Carbofed DM Drops, Decahist-DM, Pediatex-DM, Cordron-DM NR, Pseudo Carb DM, Mintex DM, PSE Carbinoxamine DM, PSE Carb DM Drops, Carboxine DM, Carboxine 12 DM, Carb PSE 12 DM, PSE Allergy DM, Cordron-12 DM, Pediatex 12 DM, QC Cough/Cold, Primatuss 4, Tricodene Sugar Free, Triaminic Softchews Cough & Runny Nose, Dimetapp Children's Long Acting Cough Plus Cold, Robitussin Cough & Cold Long-Acting, Carepanto, Triaminic Night Time Cough & Runny Nose, Scot-Tussin DM, St. Joseph HBP Cough & Cold, Robitussin Children's Nighttime Cough Long-Acting DM, SymPak DM, Broncopectol, ChlorDex GP, Quartuss, Genelan NF, Zotex-DM, Neotuss D, Extendryl DM, Donatussin DM, Ceron-DM Drops, Ceron-DM, Rondex-DM, Rondex-DM Drops, Dec-Chlorphen DM, Dec-Chlorphen DM Drops, HistadecDM, CP Dec DM, Neo DM Drops, Nasohist-DM Pediatric, Cardec DM Drops, Balamine DM, Reme Tussin DM, NoHist DM, Tussplex DM, Norel CS, Cardec DM, C-Phen DM, C-Phen DM Drops, Sildec-PE DM Drops, Sildec-PE DM, DCP Drops, EndaCof Drops, PE-Hist DM, Maxichlor PEH DM, ED DM, Poly-Tussin DM, Ricotuss, Tri-Dex PE, Z-Dex 12 D, Trigofen DM Drops, Virdec DM, Zoden DM Drops, Phenabid DM, Re DCP, Sonahist-DM, RE DCP Drops, Nohist-DMX, Bronkids, Donatussin DM Drops, Nasohist-DM, DM-PE-Chlor, CP Dec-DM Drops, PD-Cof Drops, PD-Cof, Zotex-12D, Quartuss DM, Statuss DM, Gencontuss, Giltuss Allergy Plus, NoHist-PDX, Relahist-DM, Albatussin SR, Cerose DM, Tussar DM, Liquituss R-DM, Centergy DM, Atuss DM, Father John's Medicine Plus, Norel DM, NeoTuss Plus, De-Chlor DM, De-Chlor DR, Coldtuss-DR, Tri-Vent DPC, Atuss DR, Giltuss Children's Allergy Plus Cough & Congestion, Uni-Tuss DM, Mintuss DR, Trital DM, P Chlor DM, Dex PC, Tricodene Forte, Tricodene NN, Cheracol Plus, Therahist, Triphenicol, Kophane, Threamine DM, Rhinosyn-DM, Vicks 44M Pediatric, Creomulsion Cough/Cold/Allergy, Creomulsion Pediatric, Kidcare Cough and Cold, Rescon-DM, Tanafed-DM, C-Phed DM, M-End DM, Atuss-12 DM, Dicel DM, Atuss DS, Entre-S, Maxichlor PSE DM, Kidkare Cough/Cold, Neutrahist PDX Drops, AccuHist PDX Drops, Esocor P, Mesehist DM, Triaminic-D Multi-Symptom Cold, Allres DS, Duotan DM, T-Tanna DM, Pedia Relief Cough-Cold, Deka, Dexall, Bionatuss DXP, Panatuss Pediatric DXP, G-P-Tuss DXP, Y-Cof DM, Supress A, Tussall, Tussall-ER, Supress A Pediatric, Poly Tan DM, Donatussin DM Suspension, WesTussin DM, Coryza-DM, ProHist, P-Hist, Resperal, Tannate DMP-DEX, C-Phed DPD Tann, DuraTan Forte, Dur-Tann Forte, TanDur DM, SuTan-DM, Tannate PD-DM, TanaCof DM, Tanafed DMX, Babee Cof, Silphen DM, Pertussin DM, Vicks Formula 44 Custom Care Dry Cough Suppressant, Balminil DM, Delsym 12 Hour Cough Relief for Children & Adults, Novahistine DM, Covonia Bronchial Balsam, Robitussin Cough Long-Acting, Triaminic Thin Strips Long Acting Cough, Benadryl for the Family Dry Forte, Theraflu Thin Strips Cough, Neocitran Thin Strips Cough, Contac Cough, Robafen Cough Liquidgels, Jack & Jill Thin Strips Cough, Tussinol for Dry Coughs, Dristan DM, Dexi-Tuss, Nucosef DM, Strepsils Cough Relief, Buckleys Mixture, Sucrets Cough, Pedia Relief, Triaminic Long Acting Cough, Creomulsion Children, Creomulsion, Buckley's DM, Buckley's Mixture Cough Suppressant, Tussin Cough Gels (Long Acting), Vicks Nature Fusion Cough, Duract Max Strength Cough, Scot-Tussin Diabetes, Lloydspharmacy Dry Adult Cough, Hold, 12 Hour Cough Relief, Triaminic Thin Strips Cough, Robitussin 12-Hour Cough Relief, Giltuss Honey DM 8hr Cough, Vicks Formula 44, Giltuss Children's Honey DM 8hr Cough, ElixSure Cough, Scot-Tussin DM Cough Chasers, Hold DM, Pertussin CS Childrens, Robitussin Children's Cough Long-Acting, St. Joseph Cough Suppressant, Pertussin ES, Tussin Pediatric, Robafen Pediatric Cough & Cold, Dytan-DM, Duratuss AC 12, D-Tann DM, Nighttime Cough, Safetussin PM, Robitussin Nighttime Cough DM Maximum Strength, Lortuss DM, Mastussin DM, Recofen D, Recofen Plus, Ri-Tussin DM, Robichem DM, T-Tussin DM, Tusscidin DM, Bidex-DMI, Vicks DayQuil Mucus Control DM, Humibid CS, GG-DM SR, Humigen DM, Tussidin DM, Guiat Clear DM, Guaiasorb Cough Medicine, Kita La Tos, Q-Tussin DM, Bidex-DM, Nalspan Senior DX, Vicks Formula 44 Custom Care Chesty Cough, Scot-Tussin Senior, Mucinex Fast-Max DM Max, Naldecon DX Liquigel, Safetussin 30 DM, Duratuss DM, Guiatuss Clear, Iophen DM NR, Allfen DM, PediaCare Cough & Congestion, Mucinex Children's FreeFrom Cough & Mucus, S-Pack DM, HT Tuss DM, Monafed DM, Hydro-Tuss DM, Drituss DM, Guaifen DM, Broncotron, Maxi-Tuss DM, Rompe Pecho DM, Su-Tuss DM, Biospec DMX, Muco-Fen 800 DM, Delsym Children’s Cough+ Chest Congestion DM, Guai-Dex, Guaifenesin DM SR, Tussi-Bid, Sudal DM, Ru-Tuss 800 DM, Mintab DM, Bidex-A, Mindal DM, Robitussin Children' s Cough & Chest Congestion DM, Z-Cof LA, Extuss LA, ExeFen-DM, Siltussin DM DAS Cough Formula, Simuc-DM, DuraDEX, Relacon LAX, Aquatab DM, Z-Cof LAX, Cheracol D Cough, Robafen DM Clear, DuraDEX Forte, Zotex DMX, Tussi-Organidin DM NR, Tussi-Organidin DM-S NR, Robitussin Cough + Chest Congestion Sugar-Free DM, Guaifen DM NR, Guiadrine DX, Balminil DM + Expectorant Sugar Free, Biocotron, Vicks Nature Fusion Cough & Chest Congestion, G Bid DM, Atuss-12 DX, Cheracol-D, G-Zyncof, Robafen DM Max, Guaibid DM, Robitussin Cough + Chest Congestion DM Maximum Strength, Safetussin DM, Cofex-DM, Tussin DM Clear, Congesta DM, Mucosa DM, Alka-Seltzer Plus Maximum Strength Cough & Mucus DM, TabTussin DM, Tusnel Diabetic, Siltussin-DM DAS-NA, Siltussin-DM DAS-NA Maximum Strength, Duratuss DM 12, Refenesen Chest Congestion Relief DM, Brontuss, Tussi-Organidin-DM, Chest Congestion Relief DM, Guaifenex DM, Coricidin HBP Multi-Symptom Cold (Day), Triaminic Cough & Congestion, Dex-Tuss DM, Fenesin DM IR, Tussin DM Max, Mucus Relief Cough, Gani-Tuss-DM NR, Muco-Fen DM, Guiadrine DM, Iobid DM, Q-Bid DM, Touro DM, Respa-DM, Diabetic Tussin Cough and Chest Congestion DM, Mucobid DM, Fenesin DM, Humibid DM Pediatric, Iofen-DM NF, Ambi 1000/55, Phanatuss, Giltuss Honey Cough & Chest Congestion, Naldecon Senior DX, Giltuss HBP Cough & Chest Congestion, Guiatussin-DM, Giltuss Diabetic Cough & Cold, Halotussin DM, Giltuss Children's Honey Cough & Chest Congestion, Double-Tussin DM, Halotussin DM Sugar Free, Rhinosyn-DMX, Tuss-DM, Kolephrin GG/DM, Amibid DM, Duraganidin, Genatuss DM, Glycotuss-DM, Mytussin DM, Tolu-Sed DM, Vicks Pediatric Formula 44e Cough & Chest Congestion Relief, Guiacough DM, Lotussin DM, Anti-Tuss DM, Aquabid DM, GG/DM, Robitussin Children's Cough & Cold CF, Mucinex Children's Congestion & Cough, Mucinex Children's FreeFrom Multi-Symptom Cold & Stuffy Nose, Rompe Pecho CF, Tusso-DMR, Duraphen DM, Sinutuss DM, Nortuss-DE, G-Tusicof, Zotex Pediatric, Relhist DMX, Supress-DX, G-Tron Ped, Tussi-Pres Pediatric, Giltuss Pediatrics, Pres Gen, Tussex, Tussafed-EX, GDP-EX, TriTuss, TriTuss-ER, Tussafed-EX Drops, Certuss-D (old formulation), Dynatuss EX, Dacex-PE, Anextuss, Dexcon-PE, Zotex LAX, Dacex-DM, Duraphen II DM, Duraphen Forte, Maxiphen DM, G-Phen DM, Despec DM Syrup, Guaphen Forte, Endacon, Z-Dex, Robafen CF, DuraMAX, Tusso-XR, Execof ER, Tusso-DM, Ambi 40/1000/60, Maxiphen-G DM, Z-tuss DM, Deconex DM, PDM GG, ExeTuss-DM, Despec NR Drops, Endacon DM, Q-Tussin CF, Desgen, Desgen DM, Tusslin, Robitussin Multi-Symptom Cold CF, Robitussin Multi-Symptom Cold CF Maximum Strength, Mucinex Fast-Max Day Time Severe Congestion & Cough, Mucinex Children's Day Time Multi-Symptom Cold, Giltuss Cough & Cold, Giltuss Children's Cough & Cold, Duravent DM, Zotex-EX, Nivanex DMX, Naldecon-DX Adult, Guiatuss CF, Guiatussin-CF, Naldelate DX Childrens, Naldecon-DX Pediatric, Naldelate DX Pediatric, Nalphen DX Childrens, Nalphen DX Pediatric, Ipsatol Cough Formula, Naldecon-DX Childrens, Uni Tussin CF, Pediacon DX, Phenadex, Tri-Dec, Humibid DM, Z-Cof 8DM, Entex Pac, Entre-Cough, Poly-Vent DM, Medent-DMI, Mardrops-DX, Maxifed DM, PanMist DM, Sudafed Cough, Sudafed Cough Syrup, Balminil DM + Decongestant + Expectorant, TL-Dex DM, Ambi 600/1000/30, Ambi 80/780/40, Calmylin 4, Ambi 60/580/30, Ambifed DM, Tenar DM, Novahistine DM Expectorant with Decongestant, Z-COF 12, Donatussin DM Syrup, Anatuss DM, Ambenyl-D, Dimacol, Novahistine DMX, Ru-Tuss Expectorant, Rhinosyn-X, Dorcol Childrens Cough, Syn-Rx DM, Guaifenex DM RX, Suda-Tussin DM, Pseudogest-DM, Tusnel Ped-C, Tusnel-DM Pediatric Drops, Medent DM, Daytime Liquicap, Multi Symptom Cough and Cold, Tussin Cough and Cold, Protuss DM, Med-RX DM, Tussafed-LA, Touro CC, Profen Forte DM, Profen II DM, ExeFen-DMX, Profen II DM Liquid, ExeClear-DM, S-Pak DM, Ru-Tuss DM, Aldex GS DM, Relacon-DM, Coldmist DM, Altarussin CF, Z-Cof DM(obs), Ambifed-G DM, Tusnel Pediatric, Touro CC-LD, Relacon-DM NR, Despec Drops, Pseudo Cough, Relasin DM, Z-Cof DM, Ambi 40 /400 /20, Liquicough DM, Maxifed DMX, Z-Cof 12DM, Trikof-D, Pseudo DM GG, Pseudo Max DMX, SudaTex-DM, Desgen DM (with pseudoephedrine), P-Tuss DM, Mucinex Instasoothe Sore Throat + Cough Relief, Delsym Cough+ Soothing Action, Robitussin Medi-Soothers Cough DM, Hot Lemon Cough and Colds Relief DM, PediaCare Daytime Multi-Symptom Cold, Sudafed PE Children's Cold & Cough, Albatussin Pediatric, Albatussin Pediatric Drops, Little Colds Decongestant/Cough, Children's Triacting Daytime, Safetussin CD, Triaminic Thin Strips Day Time Cold & Cough, PediaCare Children's Multi-Symptom Cold, Theraflu Thin Strips Daytime Cold and Cough, Vicks Formula 44 Custom Care Congestion, Dimetapp Toddler's Drops Decongestant Plus Cough, Codal-DM Syrup, Viravan-DM, V-Tan DM, Zotex-12, Deconsal DM Tannate, Aldex DM, Viratan-DM, Triplex DM, Codituss DM, Reme Hist DM, Pryil DM, MyHist-DM, Tannate V DM, Ru-Hist Plus, Deconsal DM, Poly Hist DM, Histex-DM, Tricodene Pediatric, Guiadex DM, Phenergan with Dextromethorphan, Promethazine with DM, Dexatrex D, Buckley's DM Decongestant, Drixoral Cough & Congestion Liquid Caps, Vicks 44D, Tussin Pediatric Cold and Cough, Balminil DM + Decongestant, Benylin DM-D, Pedia Relief Infant, Viravan-PDM, Pediatex TDM

Dextromethorphan Levels and Effects while Breastfeeding

Summary of Use during Lactation

The amounts of dextromethorphan and its active metabolite in breastmilk are very low and are not expected to affect the nursing infant. It is best to avoid the use of products with a high alcohol content while nursing.

Drug Levels

Dextromethorphan is metabolized to its active metabolite of dextrorphan by CYP2D6. Dextrorphan is further metabolized to dextrorphan glucuronide by UGT2B.

Maternal Levels. Twenty nursing mothers who were extensive metabolizers of CYP2D6 donated a blood sample and completely emptied one breast 2 hours after a single oral dose of dextromethorphan 30 mg. All mothers were at least 3 months postpartum and subjects who were poor, intermediate, or ultra-rapid metabolizers were excluded from the study. The average milk concentration of dextromethorphan at the presumed peak of 2 hours after the dose was 2.5 mcg/L (95% CI 1.5 to 3.9 mg/L). The average milk concentration of the active metabolite dextrorphan at that time was 14 mcg/L (95% CI 10.7 to 17.9 mg/L). These values translated to average “worst-case” daily infant dosages of 0.33 mcg/kg and 1.8 mcg/kg, and relative infant dosages of 0.07% and 0.41% for dextromethorphan and dextrorphan, respectively. The authors used published values of serum concentrations after a typical 60 mg twice daily dosage regimen to estimate average steady-state relative infant dosages of 0.04% and 0.07% for dextromethorphan and dextrorphan, respectively.[1] The potential contribution of dextrorphan glucuronide to infant dosage in neonates, who can deconjugate glucuronides some compounds, was not estimated.

Infant Levels. Relevant published information was not found as of the revision date.

Effects in Breastfed Infants

Relevant published information was not found as of the revision date.

Effects on Lactation and Breastmilk

Relevant published information was not found as of the revision date.

References

1.
Shum S, Yadav A, Fay E, et al. Infant dextromethorphan and dextrorphan exposure via breast milk from mothers who are CYP2D6 extensive metabolizers. J Clin Pharmacol. 2022;62:747–55. [PMC free article: PMC9153952] [PubMed: 34889461]

Substance Identification

Substance Name

Dextromethorphan

CAS Registry Number

125-71-3

Drug Class

Breast Feeding

Lactation

Milk, Human

Antitussive Agents

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Further information

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