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Medications for Reflex Sympathetic Dystrophy Syndrome

Other names: Causalgia; Complex Regional Pain Syndrome; CRPS; RSD; RSDS; Shoulder-hand syndrome; Sudeck's atrophy

What is Reflex Sympathetic Dystrophy Syndrome:  A syndrome of pain and tenderness, usually to a hand or foot, associated with vasomotor instability, skin changes and rapid development of bony demineralisation

Medications to treat Reflex Sympathetic Dystrophy Syndrome

The following list of medications are in some way related to, or used in the treatment of this condition.

Drug name Rx / OTC Pregnancy CSA Alcohol Reviews Rating Popularity
gabapentin Off Label Rx C N X 16 reviews
6.0

Generic name: gabapentin systemic

Drug class: gamma-aminobutyric acid analogs

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Off Label: Yes

 
trazodone Off Label Rx C N X 7 reviews
7.0

Generic name: trazodone systemic

Brand names:  Desyrel, Desyrel Dividose

Drug class: phenylpiperazine antidepressants

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Off Label: Yes

 
Desyrel Off Label Rx C N X Add review
10

Generic name: trazodone systemic

Drug class: phenylpiperazine antidepressants

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

Off Label: Yes

 
amitriptyline Off Label Rx C N X 3 reviews
7.0

Generic name: amitriptyline systemic

Drug class: tricyclic antidepressants

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Off Label: Yes

 
nortriptyline Off Label Rx N N X 3 reviews
3.0

Generic name: nortriptyline systemic

Drug class: tricyclic antidepressants

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Off Label: Yes

 
milnacipran Off Label Rx C N X 4 reviews
7.0

Generic name: milnacipran systemic

Drug class: serotonin-norepinephrine reuptake inhibitors

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph

Off Label: Yes

 
pregabalin Off Label Rx C 5 X 14 reviews
7.0

Generic name: pregabalin systemic

Drug class: gamma-aminobutyric acid analogs

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph

Off Label: Yes

 
doxepin Off Label Rx N N X 1 review
3.0

Generic name: doxepin systemic

Drug class: miscellaneous anxiolytics, sedatives and hypnotics, tricyclic antidepressants

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Off Label: Yes

 
carbamazepine Off Label Rx D N X Add review
4.0

Generic name: carbamazepine systemic

Drug class: dibenzazepine anticonvulsants

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Off Label: Yes

 
Desyrel Dividose Off Label Rx C N X Add review Add

Generic name: trazodone systemic

Drug class: phenylpiperazine antidepressants

For consumers: dosage, interactions, side effects

Off Label: Yes

 

Learn more about Reflex Sympathetic Dystrophy Syndrome

Legend

Off Label This medication may not be approved by the FDA for the treatment of this condition.
Prescription Only / Over the Counter
Rx Prescription Only
OTC Over the Counter
Rx/OTC Prescription or Over the Counter
Pregnancy
A Adequate and well-controlled studies have failed to demonstrate a risk to the fetus in the first trimester of pregnancy (and there is no evidence of risk in later trimesters).
B Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women.
C Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
D There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
X Studies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use in pregnant women clearly outweigh potential benefits.
N FDA has not classified the drug.
Controlled Substances Act Schedule
N Is not subject to the Controlled Substances Act.
1 Has a high potential for abuse. Has no currently accepted medical use in treatment in the United States. There is a lack of accepted safety for use under medical supervision.
2 Has a high potential for abuse. Has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse may lead to severe psychological or physical dependence.
3 Has a potential for abuse less than those in schedules 1 and 2. Has a currently accepted medical use in treatment in the United States. Abuse may lead to moderate or low physical dependence or high psychological dependence.
4 Has a low potential for abuse relative to those in schedule 3. It has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 3.
5 Has a low potential for abuse relative to those in schedule 4. Has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 4.
Alcohol
X Interacts with Alcohol.

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