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How does Aimovig work to prevent migraine?

Medically reviewed by Last updated on Jun 19, 2018.

Official Answer


Aimovig (erenumab-aooe) works to help prevent chronic migraine headaches by blocking the activity of calcitonin gene-related peptide (CGRP), a molecule that is involved in migraine attacks and rises during an attack.

The calcitonin gene-related peptide (CGRP) receptor antagonists are a new class of drugs for migraine. Aimovig, from Amgen, is also the first fully human monoclonal antibody for migraine prevention. This treatment for adults is given once-a-month by subcutaneous (under the skin) self-injections with an auto-injector type pen or a single-dose prefilled syringe.

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