Atogepant Dosage
Medically reviewed by Drugs.com. Last updated on Oct 10, 2024.
Applies to the following strengths: 60 mg; 10 mg; 30 mg
Usual Adult Dose for:
Additional dosage information:
Usual Adult Dose for Migraine Prophylaxis
Episodic migraine: 10 mg, 30 mg, or 60 mg orally once a day
Chronic migraine: 60 mg orally once a day
Use: For the preventative treatment of episodic and chronic migraine
Renal Dose Adjustments
- Mild to Moderate Renal Dysfunction : No adjustment recommended
- Severe Renal Dysfunction and ESRD (CrCl less than 30 mL/min):
- Episodic migraine: 10 mg orally once a day
- Chronic migraine: Avoid use
Liver Dose Adjustments
- Mild to moderate hepatic impairment : No adjustment recommended
- Severe hepatic impairment : Avoid use
Dose Adjustments
Elderly: Dose selection should be cautious, generally starting at the low end of the dosing range.
Concomitant CYP450 3A4 Inducers/Inhibitors:
- Strong CYP450 3A4 inhibitors:
- Episodic migraine: 10 mg orally once a day
- Chronic migraine: Avoid use
- Strong, moderate, or weak CYP450 3A4 inducers:
- Episodic migraine: 30 mg or 60 mg orally once a day
- Chronic migraine: Avoid use
- OATP inhibitors:
- Episodic migraine: 10 mg or 30 mg orally once a day
- Chronic migraine: 30 mg orally once a day
Precautions
CONTRAINDICATIONS:
- History of hypersensitivity to this drug or any of the components
Report Adverse Reactions at www.fda.gov/medwatch.
Safety and efficacy have not been established in patients younger than 18 years.
Consult WARNINGS section for additional precautions.
Dialysis
For patients undergoing intermittent dialysis: 10 mg orally once a day with dose to be administered after dialysis
Other Comments
Administration advice:
- Take orally once a day with or without food.
Storage:
- Store between 20C and 25C (68F and 77F), with excursions permitted between 15C and 30C (59F and 86F).
Patient advice:
- Read the Patient Information and Instructions for Use.
- Patients should understand that this drug may interact with other drugs and dose adjustments may be necessary; patients should be instructed to report use of all prescription medications, over-the-counter medications, herbal products, and/or grapefruit to their healthcare provider.
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Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.