Treximet Interactions
There are 536 drugs known to interact with Treximet (naproxen/sumatriptan), along with 15 disease interactions, and 6 alcohol/food interactions. Of the total drug interactions, 169 are major, 350 are moderate, and 17 are minor.
- View all 536 medications that may interact with Treximet
- View Treximet alcohol/food interactions (6)
- View Treximet disease interactions (15)
Most frequently checked interactions
View interaction reports for Treximet (naproxen / sumatriptan) and the medicines listed below.
- amitriptyline
- baclofen
- clonazepam
- cyclobenzaprine
- Cymbalta (duloxetine)
- Flexeril (cyclobenzaprine)
- gabapentin
- hydroxyzine
- ibuprofen
- Klonopin (clonazepam)
- Lamictal (lamotrigine)
- levothyroxine
- Lexapro (escitalopram)
- Lyrica (pregabalin)
- Nexium (esomeprazole)
- omeprazole
- prednisone
- propranolol
- Singulair (montelukast)
- sumatriptan
- Synthroid (levothyroxine)
- tizanidine
- Topamax (topiramate)
- topiramate
- tramadol
- trazodone
- Vitamin D3 (cholecalciferol)
- Xanax (alprazolam)
- Zoloft (sertraline)
- Zyrtec (cetirizine)
Treximet alcohol/food interactions
There are 6 alcohol/food interactions with Treximet (naproxen / sumatriptan).
Treximet disease interactions
There are 15 disease interactions with Treximet (naproxen / sumatriptan) which include:
- CAD risk factors
- cardiovascular disease
- asthma
- fluid retention
- GI toxicity
- rash
- renal toxicities
- thrombosis
- liver disease
- sodium
- anemia
- hepatotoxicity
- hyperkalemia
- platelet aggregation inhibition
- seizure disorders
Report options
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More about Treximet (naproxen / sumatriptan)
- Treximet consumer information
- Compare alternatives
- Pricing & coupons
- Reviews (92)
- Drug images
- Side effects
- Dosage information
- During pregnancy
- Generic availability
- FDA approval history
- Drug class: antimigraine agents
- En español
Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
