Treximet Interactions
There are 538 drugs known to interact with Treximet (naproxen/sumatriptan), along with 15 disease interactions, and 6 alcohol/food interactions. Of the total drug interactions, 169 are major, 351 are moderate, and 18 are minor.
- View all 538 medications that may interact with Treximet
- View Treximet alcohol/food interactions (6)
- View Treximet disease interactions (15)
Most frequently checked interactions
View interaction reports for Treximet (naproxen / sumatriptan) and the medicines listed below.
- amitriptyline
- baclofen
- clonazepam
- cyclobenzaprine
- Cymbalta (duloxetine)
- Flexeril (cyclobenzaprine)
- gabapentin
- hydroxyzine
- ibuprofen
- Klonopin (clonazepam)
- Lamictal (lamotrigine)
- levothyroxine
- Lexapro (escitalopram)
- Lyrica (pregabalin)
- Nexium (esomeprazole)
- omeprazole
- prednisone
- propranolol
- Singulair (montelukast)
- sumatriptan
- Synthroid (levothyroxine)
- tizanidine
- Topamax (topiramate)
- topiramate
- tramadol
- trazodone
- Vitamin D3 (cholecalciferol)
- Xanax (alprazolam)
- Zoloft (sertraline)
- Zyrtec (cetirizine)
Treximet alcohol/food interactions
There are 6 alcohol/food interactions with Treximet (naproxen / sumatriptan).
Treximet disease interactions
There are 15 disease interactions with Treximet (naproxen / sumatriptan) which include:
- CAD risk factors
- cardiovascular disease
- asthma
- fluid retention
- GI toxicity
- rash
- renal toxicities
- thrombosis
- liver disease
- sodium
- anemia
- hepatotoxicity
- hyperkalemia
- platelet aggregation inhibition
- seizure disorders
Report options
More about Treximet (naproxen / sumatriptan)
- Treximet consumer information
- Compare alternatives
- Pricing & coupons
- Reviews (92)
- Drug images
- Side effects
- Dosage information
- During pregnancy
- Generic availability
- FDA approval history
- Drug class: antimigraine agents
- En español
Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Topamax
Topamax (topiramate) is used to prevent seizures in adults and children and to prevent migraine ...
Sumatriptan
Sumatriptan systemic is used for cluster headaches, cyclic vomiting syndrome, migraine, new daily ...
Metoclopramide
Metoclopramide is used short-term to treat heartburn caused by gastroesophageal reflux. Learn about ...
Celecoxib
Celecoxib is a nonsteroidal anti-inflammatory drug (NSAID) used to treat pain or inflammation ...
Topiramate
Topiramate systemic is used for bipolar disorder, borderline personality disorder, bulimia ...
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
