Zavegepant nasal

Generic name: zavegepant nasal
Brand name: Zavzpret
Dosage form: nasal spray (10 mg)
Drug class: CGRP inhibitors

Medically reviewed by Drugs.com on Aug 16, 2023. Written by Cerner Multum.

What is zavegepant nasal?

Zavegepant nasal (for use in the nose) is used in adults to treat migraine headaches with or without aura.

Zavegepant nasal will not prevent migraines.

Zavegepant nasal may also be used for purposes not listed in this medication guide.

Zavegepant nasal side effects

Get emergency medical help if you have signs of an allergic reaction: hives, difficult breathing, swelling of your face, lips, tongue, or throat.

Common side effects of zavegepant nasal may include:

• changes in your sense of taste;

• nausea, vomiting; or

• nasal discomfort.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Warnings

Use only as directed. Tell your doctor if you use other medicines or have other medical conditions or allergies.

Before taking this medicine

You should not use zavegepant nasal if you are allergic to it.

Tell your doctor if you have or have ever had:

• liver or kidney disease.

Tell your doctor if you are pregnant or breastfeeding.

How should I use zavegepant nasal?

Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.

Do not take zavegepant nasal by mouth. It is for use only in the nasal inhaler device provided with zavegepant nasal.

Zavegepant nasal is usually given as a single spray into only one of your nostrils. Do not test, prime, or press the device plunger before use.

Do not use this medicine in both nostrils.

To use the nasal spray:

• Blow your nose gently. With your head upright insert the tip of bottle into one nostril and press your other nostril closed. Breathe in and spray the medicine into your nose.

• If the spray gets in your eyes or mouth or on your skin, rinse with water.

• Do not blow your nose for a few minutes. Do not use more than 1 spray (10 mg) of zavegepant nasal within 24 hours or 8 sprays within 30 days.

Each nasal spray is for one use only (in one nostril). Throw the nasal spray away after one use or once the medicine has expired.

Store the unused nasal spray in the original package at room temperature away from moisture and heat. Do not freeze.

Zavegepant nasal dosing information

Usual Adult Dose for Migraine:

For acute treatment of migraine: Nasal spray: 10 mg given as a single spray in one nostril, as needed
Maximum dose: 10 mg (one spray) in a 24-hour period

Comments:
-The safety of treating more than 8 migraines in a 30-day period is unknown.

Use: For the acute treatment of migraine with or without aura in adults.

What happens if I miss a dose?

Zavegepant nasal is used when needed and does not have a daily dose. Call your doctor if the medicine is not effective.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What should I avoid while using zavegepant nasal?

Do not use other medications for your nose unless your doctor tells you to.

What other drugs will affect zavegepant nasal?

Avoid using a nasal decongestant within 1 hour after you use zavegepant nasal.

Other drugs may affect zavegepant, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all other medicines you use.

Further information

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer

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