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Generic name: lasmiditan
Brand name: Reyvow
Dosage form: oral tablet
Drug class: Antimigraine agents

Medically reviewed by Philip Thornton, DipPharm. Last updated on Apr 4, 2023.

What is lasmiditan?

Lasmiditan is a type of drug called a ditan. It is an abortive migraine medication, which means it is used to help treat a migraine attack rather than prevent a migraine headache. Lasmiditan comes as a tablet.

In 2020, lasmiditan was the first ditan to be approved by the US Food and Drug Administration (FDA).

Lasmiditan works by blocking the pain pathways in the brain. It is a serotonin (5-HT)1F receptor agonist, but its exact mechanism of action is unknown.

Unlike triptans, which are the gold-standard of treatment for migraines, lasmiditan does not constrict blood vessels in the heart and brain.

What is lasmiditan used for?

Lasmiditan is a prescription medicine used for the acute treatment of migraine attacks with or without aura in adults.

Important information

What should I tell my doctor before taking lasmiditan?

Before you take lasmiditan, tell your healthcare provider about all of your medical conditions, including if you:

How should I take lasmiditan?

What should I avoid while taking lasmiditan?

Do not drive or operate machinery for at least 8 hours after taking lasmiditan.

You should not drink alcohol or take other medicines that make you drowsy while taking lasmiditan.

Dosing information

What are the side effects of lasmiditan?

Lasmiditan can cause serious side effects including:

The most common side effects of lasmiditan include:

Tell your healthcare provider if you have any side effect that bothers you or that does not go away.

These are not all of the possible side effects of lasmiditan. For more information ask your healthcare provider or pharmacist.

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. You may also report side effects to Lilly at 1-800-LillyRx (1-800-545-5979).


Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. Your healthcare provider will decide if you can take lasmiditan with your other medicines.

Especially, tell your healthcare provider if you take:

Ask your healthcare provider or pharmacist for a list of these medicines if you are not sure.

Know the medicines you take. Keep a list of them and show it to your healthcare provider or pharmacist when you get a new medicine.

Pregnancy and breastfeeding

Tell your doctor if your are pregnant or plan to become pregnant. It is not known if lasmiditan will harm your unborn baby.

There is a pregnancy registry for women who take lasmiditan. The purpose of this registry is to collect information about the health of you and your baby. To learn more call 1-833-464-4724 or visit You may also talk to your healthcare provider about how you can take part in this registry.

Tell your doctor if you are breastfeeding or plan to breastfeed. It is not known if lasmiditan passes into your breastmilk.


What are the ingredients in lasmiditan?

Active ingredient: lasmiditan hemisuccinate

Inactive ingredients: croscarmellose sodium, magnesium stearate, microcrystalline cellulose, pregelatinized starch, sodium lauryl sulfate.

Color mixture ingredients: black ferric oxide, polyethylene glycol, polyvinyl alcohol, talc, titanium dioxide. 100 mg tablets also contain red ferric oxide.

Lasmiditan is marketed under the brandname Reyvow by Lilly USA, LLC, Indianapolis, IN 46285, USA

Frequently asked questions

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.