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Eptinezumab Side Effects

Medically reviewed by Last updated on Dec 24, 2023.

Applies to eptinezumab: intravenous solution.

Serious side effects of Eptinezumab

Along with its needed effects, eptinezumab may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur while taking eptinezumab:

Less common

Incidence not known

Other side effects of Eptinezumab

Some side effects of eptinezumab may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

Incidence not known

For Healthcare Professionals

Applies to eptinezumab: intravenous solution.


The most commonly reported adverse reactions were nasopharyngitis and hypersensitivity.[Ref]


Common (1% to 10%): Hypersensitivity (including angioedema, urticaria, flushing, rash

and pruritus)

Postmarketing reports: Anaphylactic reactions (including hypotension and respiratory difficulties)


Very common (10% or more): Anti-drug antibodies (up to 20.6%)


Uncommon (less than 2%): Infusion-site reactions including extravasation


Common (1% to 10%): Fatigue


Common (1% to 10%): Nasopharyngitis

Frequency not reported (infusion-related respiratory symptoms): Nasal congestion, rhinorrhea, throat irritation, cough, sneezing, dyspnea

Frequently asked questions


1. (2022) "Product Information. Vyepti (eptinezumab)." Lundbeck Inc

2. (2022) "Product Information. Vyepti (eptinezumab)." Lundbeck Ltd

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.