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Eptinezumab Side Effects

Medically reviewed by Last updated on March 16, 2020.

For the Consumer

Applies to eptinezumab: intravenous solution


Before using eptinezumab tell your doctor about all your medical conditions or allergies, all medicines you use, and if you are pregnant or breastfeeding.

Get emergency medical help if you have signs of an allergic reaction: hives, rash; sudden warmth or tingling; difficult breathing; redness or swelling of your face, lips, tongue, or throat.

Some side effects may occur during the injection. Tell your caregiver if you feel warm, itchy, or light-headed.

Common side effects may include:

  • stuffy nose;

  • throat irritation; or

  • allergic reaction.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.

For Healthcare Professionals

Applies to eptinezumab: intravenous solution


The most commonly reported adverse reactions have been nasopharyngitis and hypersensitivity.[Ref]


Common (1% to 10%): Hypersensitivity

Hypersensitivity reactions included terms, such as hypersensitivity, pruritus, and flushing/hot flush, occurring on the day of dosing. Hypersensitivity was reported in 1% and 2% of patients receiving a dose of 100 mg or 300 mg, respectively


Common (1% to 10%): Nasopharyngitis


1. "Product Information. Vyepti (eptinezumab)." Lundbeck Inc, Deerfield, IL.

Frequently asked questions

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.