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Advil Migraine

Generic name: ibuprofenEYE-bue-PROE-fen ]
Brand names: Advil, Advil Migraine, Children's Advil, Children's Ibuprofen Berry, Children's Motrin, ... show all 17 brands
Drug class: Nonsteroidal anti-inflammatory drugs

Medically reviewed by Drugs.com on Sep 20, 2023. Written by Cerner Multum.

What is Advil Migraine?

Advil Migraine is a nonsteroidal anti-inflammatory drug (NSAID).

Advil Migraine is used to reduce fever and treat pain or inflammation caused by many conditions such as headache, toothache, back pain, arthritis, menstrual cramps, or minor injury. Advil Migraine is used in adults and children who are at least 6 months old.

Advil Migraine may also be used for purposes not listed in this medication guide.

Advil Migraine side effects

Get emergency medical help if you have signs of an allergic reaction (hives, difficult breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning eyes, skin pain, red or purple skin rash with blistering and peeling).

Get emergency medical help if you have signs of a heart attack or stroke: chest pain spreading to your jaw or shoulder, sudden numbness or weakness on one side of the body, slurred speech, leg swelling, feeling short of breath.

Advil Migraine may cause serious side effects. Stop using Advil Migraine and call your doctor at once if you have:

  • changes in your vision;

  • shortness of breath (even with mild exertion);

  • swelling or rapid weight gain;

  • a skin rash, no matter how mild;

  • signs of stomach bleeding--bloody or tarry stools, coughing up blood or vomit that looks like coffee grounds;

  • liver problems--nausea, upper stomach pain, itching, tired feeling, flu-like symptoms, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes);

  • low red blood cells (anemia)--pale skin, feeling light-headed or short of breath, rapid heart rate, trouble concentrating; or

  • kidney problems--little or no urinating, painful or difficult urination, swelling in your feet or ankles, feeling tired or short of breath.

Common side effects of Advil Migraine may include:

  • nausea, vomiting, gas;

  • bleeding; or

  • dizziness, headache.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Warnings

Advil Migraine can increase your risk of fatal heart attack or stroke. Do not use Advil Migraine just before or after heart bypass surgery (coronary artery bypass graft, or CABG). This medicine may also cause stomach or intestinal bleeding, which can be fatal.

Before taking this medicine

Advil Migraine can increase your risk of fatal heart attack or stroke, even if you don't have any risk factors. Do not use this medicine just before or after heart bypass surgery (coronary artery bypass graft, or CABG).

Advil Migraine may also cause stomach or intestinal bleeding, which can be fatal. These conditions can occur without warning while you are using this medicine, especially in older adults.

You should not use Advil Migraine if you are allergic to it, or if you have ever had an asthma attack or severe allergic reaction after taking aspirin or an NSAID.

Ask a doctor or pharmacist if this medicine is safe to use if you have ever had:

  • heart disease, high blood pressure, high cholesterol, diabetes, or if you smoke;

  • a heart attack, stroke, or blood clot;

  • stomach ulcers or bleeding;

  • liver or kidney disease;

  • asthma; or

  • if you take aspirin to prevent heart attack or stroke.

Ask a doctor before using this medicine if you are pregnant or breastfeeding.

If you are pregnant, you should not take Advil Migraine unless your doctor tells you to. Taking an NSAID during the last 20 weeks of pregnancy can cause serious heart or kidney problems in the unborn baby and possible complications with your pregnancy.

Do not give Advil Migraine to a child younger than 6 months old without the advice of a doctor.

How should I take Advil Migraine?

Use exactly as directed on the label, or as prescribed by your doctor. Use the lowest dose that is effective in treating your condition.

An Advil Migraine overdose can damage your stomach or intestines. The maximum amount of ibuprofen for adults is 800 milligrams per dose or 3200 mg per day (4 maximum doses).

A child's dose of ibuprofen is based on the age and weight of the child. Carefully follow the dosing instructions provided with children's Advil Migraine for the age and weight of your child. Ask a doctor or pharmacist if you have questions.

Take Advil Migraine with food or milk to lessen stomach upset.

Shake the oral suspension (liquid) before you measure a dose. Use the dosing syringe provided, or use a medicine dose-measuring device (not a kitchen spoon).

You must chew the chewable tablet before you swallow it.

Store at room temperature away from moisture and heat. Do not allow the liquid medicine to freeze.

What happens if I miss a dose?

Since Advil Migraine is used when needed, you may not be on a dosing schedule. Skip any missed dose if it's almost time for your next dose. Do not use two doses at one time.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. Overdose symptoms may include nausea, vomiting, stomach pain, drowsiness, black or bloody stools, coughing up blood, shallow breathing, fainting, or coma.

What should I avoid while taking Advil Migraine?

Ask a doctor or pharmacist before using other medicines for pain, fever, swelling, or cold/flu symptoms. They may contain ingredients similar to Advil Migraine (such as aspirin, this medicine, ketoprofen, or naproxen).

Avoid taking aspirin unless your doctor tells you to.

If you also take aspirin to prevent stroke or heart attack, taking Advil Migraine can make aspirin less effective in protecting your heart and blood vessels. If you take both medicines, take this medicine at least 8 hours before or 30 minutes after you take aspirin (non-enteric coated form).

Avoid drinking alcohol. It may increase your risk of stomach bleeding.

What other drugs will affect Advil Migraine?

Ask your doctor before using Advil Migraine if you take an antidepressant. Taking certain antidepressants with an NSAID may cause you to bruise or bleed easily.

Ask a doctor or pharmacist before using Advil Migraine with any other medications, especially:

  • cyclosporine;

  • lithium;

  • methotrexate;

  • a blood thinner (warfarin, Coumadin, Jantoven);

  • heart or blood pressure medication, including a diuretic or "water pill"; or

  • steroid medicine (such as prednisone).

This list is not complete. Other drugs may affect Advil Migraine, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.

Popular FAQ

There are no known drug interactions between Ajovy (fremanezumab) and ibuprofen (Advil, Motrin), but you should talk to your doctor before you combine these medications. Serious side effects can occur with ibuprofen, such as stomach or intestinal bleeding, rash, swelling, problems with your kidneys, or an increased risk of heart attack and stroke.

Ajovy is used to help prevent migraine episodes in adults. Ibuprofen is an over-the-counter analgesic used as an acute treatment to help stop migraine pain already in progress. If Ajovy is not adequately helping your migraine, your doctor may want to switch you to a different migraine prevention medicine or drug class.

Ibuprofen is short acting, while naproxen is long acting and more likely to cause an upset stomach. Naproxen and ibuprofen are both NSAIDs so they are similar in many ways, but there are important differences. Continue reading

Even though aspirin and Ibuprofen are both NSAIDs (nonsteroidal anti-inflammatory drugs) and work similarly, there are several differences between the two drugs and they are not considered interchangeable. Continue reading

Despite popular belief that you have to take ibuprofen with food, you can take ibuprofen on an empty stomach and this will give you faster pain relief than taking it with food. Food increases the time it takes for ibuprofen to be absorbed, although it won't affect how much is absorbed. There is actually no evidence that taking ibuprofen with food prevents gastric irritation – ibuprofen at OTC doses has a low incidence of gastric irritation anyway. Continue reading

Although taking expired ibuprofen is not recommended by the manufacturer, the actual shelf-life is likely to be longer than that indicated by the expiry date, with FDA testing showing many drugs are active for years beyond their expiry date, although specific data on ibuprofen is not available. Within reason, an ibuprofen tablet that is a few months past its expiry date is probably safe to take. Ibuprofen that is years past its expiry date should not be taken. Continue reading

More FAQ

Further information

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.