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Amerge Side Effects

Generic Name: naratriptan

Note: This page contains information about the side effects of naratriptan. Some of the dosage forms included on this document may not apply to the brand name Amerge.

For the Consumer

Applies to naratriptan: oral tablet

In addition to its needed effects, some unwanted effects may be caused by naratriptan (the active ingredient contained in Amerge). In the event that any of these side effects do occur, they may require medical attention.

Major Side Effects

You should check with your doctor immediately if any of these side effects occur when taking naratriptan:

More common:
  • Chest pain (severe)
  • heaviness, tightness, or pressure in the chest, throat, or neck
  • sensation of burning, warmth, heat, numbness, tightness, or tingling
Less common:
  • Burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings
Less common or rare:
  • Convulsions (seizures)
  • irregular heartbeat
  • slow heartbeat

Minor Side Effects

Some of the side effects that can occur with naratriptan may not need medical attention. As your body adjusts to the medicine during treatment these side effects may go away. Your health care professional may also be able to tell you about ways to reduce or prevent some of these side effects. If any of the following side effects continue, are bothersome or if you have any questions about them, check with your health care professional:

Less common:
  • Anxiety
  • bone pain
  • change in taste sensation
  • chills or fever
  • difficulty with sleeping
  • eye problems
  • fainting
  • general feeling of discomfort or illness
  • joint pain
  • muscle or joint stiffness, tightness, or rigidity
  • pounding heartbeat
  • stomach discomfort or pain
  • trembling or shaking of the hands or feet
  • unusual tiredness or weakness

For Healthcare Professionals

Applies to naratriptan: oral tablet


The most commonly reported adverse reactions have included paresthesias, dizziness, drowsiness, malaise/fatigue, and throat/neck symptoms.[Ref]


Common (1% to 10%): Palpitations, chest pain and discomfort, chest pressure/heaviness
Uncommon (0.1% to 1%): Bradycardia, tachycardia
Very rare (less than 0.01%): Peripheral vascular ischemia, coronary artery vasospasm, transient ischemic ECG changes, angina, myocardial infarctions
Frequency not reported: Acute myocardial infarction, increased blood pressure[Ref]


Common (1% to 10%): Malaise/fatigue, sensations of pain or pressure, heaviness or tightness (maybe of throat/neck/chest), warm-hot sensation, vertigo[Ref]

Nervous system

Common (1% to 10%): Paresthesias, dizziness, drowsiness, headaches
Rare (0.01% to 0.1%): Somnolence[Ref]


Common (1% to 10%): Nausea, vomiting, hyposalivation
Rare (0.01% to 0.1%): Ischemic colitis[Ref]


Uncommon (0.1% to 1%): Visual disturbance, photophobia[Ref]


Common (1% to 10%): Musculoskeletal pain, muscle stiffness, tightness and rigidity[Ref]


Rare (0.01% to 0.1%): Anaphylaxis, hypersensitivity reactions including cutaneous hypersensitivity and angioedema[Ref]


Rare (0.01% to 0.1%): Rash, urticaria, pruritus, facial edema[Ref]


1. Cerner Multum, Inc. "Australian Product Information." O 0

2. Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0

3. "Product Information. Amerge (naratriptan)." Glaxo Wellcome, Research Triangle Park, NC.

Not all side effects for Amerge may be reported. You should always consult a doctor or healthcare professional for medical advice. Side effects can be reported to the FDA here.

Disclaimer: Every effort has been made to ensure that the information provided is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate safety, effectiveness, or appropriateness for any given patient. does not assume any responsibility for any aspect of healthcare administered with the aid of materials provided. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the substances you are taking, check with your doctor, nurse, or pharmacist.