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Acetaminophen / Aspirin / Caffeine Dosage

Medically reviewed by Drugs.com. Last updated on Jul 26, 2024.

Applies to the following strengths: 250 mg-250 mg-65 mg; 160 mg-230 mg-33 mg; 260 mg-520 mg-32.5 mg; 500 mg-500 mg-65 mg; 325 mg-500 mg-65 mg; 194 mg-227 mg-33 mg

Usual Adult Dose for:

Usual Pediatric Dose for:

Additional dosage information:

Usual Adult Dose for Analgesic/Antipyretic

2 tablets orally every 6 hours
Maximum dose: 8 tablets in 24 hours

Each tablet contains: acetaminophen 250 mg/aspirin 250 mg/caffeine 65 mg

Comments:


Uses: For the temporary relief of minor aches and pains due to headache, cold, arthritis, muscular aches, toothache, or premenstrual or menstrual cramps.

Usual Pediatric Dose for Analgesic/Antipyretic

12 years or older:

2 tablets orally every 6 hours
Maximum dose: 8 tablets in 24 hours

Each tablet contains: acetaminophen 250 mg/aspirin 250 mg/caffeine 65 mg

Comments:


Uses: For the temporary relief of minor aches and pains due to headache, cold, arthritis, muscular aches, toothache, or premenstrual or menstrual cramps.

Renal Dose Adjustments

Use with caution; generally, aspirin is not recommended for use in severe renal impairment (CrCl less than 10 mL/minute) due to the potential for increased risk of salicylate toxicity

Liver Dose Adjustments

Use with caution; chronic use of acetaminophen is not recommended in patients with liver disease and aspirin is not recommended in patients with severe hepatic impairment due to increased risk of clinically significant bleeding and other adverse effects

Precautions

CONTRAINDICATIONS:


Safety and efficacy have not been established in patients younger than 12 years.

Consult WARNINGS section for additional precautions

Dialysis

Data not available

Other Comments

Administration advice:
Tablets: Take orally with a full glass of water

General:


Monitoring:

Patient advice:

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.