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Lacosamide (oral/injection)

Generic Name: lacosamide (oral/injection) (la KOE sa mide)
Brand Name: Vimpat

Medically reviewed on April 10, 2018

What is lacosamide?

Lacosamide is an anti-epileptic drug, also called an anticonvulsant.

Lacosamide is used together with other medications to treat partial-onset seizures in adults and children who are at least 4 years old.

Lacosamide may also be used for purposes not listed in this medication guide.

Important Information

Do not stop using lacosamide suddenly or you may have increased seizures.

Some people have thoughts about suicide while taking lacosamide. Stay alert to changes in your mood or symptoms. Report any new or worsening symptoms to your doctor.

You may feel faint while taking lacosamide. Call your doctor right away if you have fast or pounding heartbeats, shortness of breath, and sudden dizziness.

Before taking this medicine

You should not use lacosamide if you are allergic to it.

Tell your doctor if you have ever had:

  • heart disease;

  • kidney disease;

  • liver disease;

  • depression, suicidal thoughts or actions;

  • drug or alcohol addiction;

  • nerve problems caused by diabetes; or

  • phenylketonuria/PKU (lacosamide liquid may contain phenylalanine).

Some people have thoughts about suicide while taking lacosamide. Your doctor will need to check your progress at regular visits. Your family or other caregivers should also be alert to changes in your mood or symptoms.

Call your doctor if you have new or worsening depression or suicidal thoughts during the first several months of treatment, or whenever your dose is changed.

Follow your doctor's instructions about taking seizure medication if you are pregnant. Seizure control is very important during pregnancy, and having a seizure could harm both mother and baby. Do not start or stop taking this medicine without your doctor's advice, and tell your doctor right away if you become pregnant.

If you are pregnant, your name may be listed on a pregnancy registry to track the effects of lacosamide on the baby.

It may not be safe to breast-feed a baby while you are using this medicine. Ask your doctor about any risks.

Lacosamide is not approved for use by anyone younger than 4 years old.

How should I take lacosamide?

Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed.

Lacosamide tablets or liquid can be taken with or without food.

Measure liquid medicine carefully. Use the dosing syringe provided, or use a medicine dose-measuring device (not a kitchen spoon).

Lacosamide injection is given as an infusion into a vein. A healthcare provider will give you this injection if you are unable to take the medicine by mouth.

Call your doctor if your seizures get worse or you have them more often while taking lacosamide.

Do not stop using lacosamide suddenly, even if you feel fine. Stopping suddenly may cause increased seizures. Follow your doctor's instructions about tapering your dose.

In case of emergency, wear or carry medical identification to let others know you use seizure medication.

Store at room temperature away from moisture and heat. Do not freeze the liquid form of lacosamide. Throw away any liquid not used within 7 weeks after opening the bottle.

Keep track of your medicine. Lacosamide is a drug of abuse and you should be aware if anyone is using your medicine improperly or without a prescription.

What happens if I miss a dose?

Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.

Get your prescription refilled before you run out of medicine completely.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What should I avoid while taking lacosamide?

lacosamide may cause dizziness or blurred vision, and may impair your reactions. Avoid driving or hazardous activity until you know how this medicine will affect you.

Lacosamide side effects

Get emergency medical help if you have signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Seek medical treatment if you have a serious drug reaction that can affect many parts of your body. Symptoms may include: skin rash, fever, swollen glands, flu-like symptoms, muscle aches, swelling in your legs, tiredness, dark urine, or yellowing of your skin or eyes. This reaction may occur several weeks after you began using lacosamide.

Report any new or worsening symptoms to your doctor, such as: mood or behavior changes, depression, anxiety, panic attacks, trouble sleeping, or if you feel impulsive, irritable, agitated, hostile, aggressive, restless, hyperactive (mentally or physically), or have thoughts about suicide or hurting yourself.

Call your doctor at once if you have:

  • a light-headed feeling, like you might pass out;

  • severe dizziness;

  • problems with balance or muscle movement;

  • shortness of breath; or

  • fast, slow, or pounding heartbeats, fluttering in your chest.

Common side effects may include:

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1 800 FDA 1088.

See also: Side effects (in more detail)

What other drugs will affect lacosamide?

Other drugs may affect lacosamide, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.

Further information

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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