Carbamate anticonvulsants

Carbamate anticonvulsant agents are newer antiepileptic drugs whose exact mechanism of action is uncertain. It has some inhibitory effect at the N-methyl-D-aspartate (NMDA) receptors and slightly potentiates gamma-aminobutyric acid (GABA) activity. It has a broad spectrum of activity but is only used in patients who are unresponsive to other anticonvulsant drugs, as it can cause severe reactions such as aplastic anemia, hepatitis and liver failure.