Zonisamide Interactions
There are 413 drugs known to interact with zonisamide, along with 11 disease interactions, and 1 alcohol/food interaction. Of the total drug interactions, 101 are major, 307 are moderate, and 5 are minor.
- View all 413 medications that may interact with zonisamide
- View zonisamide alcohol/food interactions (1)
- View zonisamide disease interactions (11)
Most frequently checked interactions
View interaction reports for zonisamide and the medicines listed below.
- Abilify (aripiprazole)
- Adderall (amphetamine / dextroamphetamine)
- Aimovig (erenumab)
- Benadryl (diphenhydramine)
- Cymbalta (duloxetine)
- Fish Oil (omega-3 polyunsaturated fatty acids)
- Flexeril (cyclobenzaprine)
- Keppra (levetiracetam)
- Klonopin (clonazepam)
- Lamictal (lamotrigine)
- Lexapro (escitalopram)
- Lyrica (pregabalin)
- Metoprolol Succinate ER (metoprolol)
- MiraLAX (polyethylene glycol 3350)
- Nurtec ODT (rimegepant)
- ProAir HFA (albuterol)
- Singulair (montelukast)
- Synthroid (levothyroxine)
- Topamax (topiramate)
- Tylenol (acetaminophen)
- Ubrelvy (ubrogepant)
- Vimpat (lacosamide)
- Vitamin B12 (cyanocobalamin)
- Vitamin C (ascorbic acid)
- Vitamin D3 (cholecalciferol)
- Vyvanse (lisdexamfetamine)
- Xanax (alprazolam)
- Zofran (ondansetron)
- Zoloft (sertraline)
- Zyrtec (cetirizine)
Zonisamide alcohol/food interactions
There is 1 alcohol/food interaction with zonisamide.
Zonisamide disease interactions
There are 11 disease interactions with zonisamide which include:
- bone marrow depression/blood dyscrasias
- oligohidrosis/hyperthermia
- severe liver disease
- hematologic toxicity
- hypersensitivity reactions
- depression
- suicidal tendency
- renal dysfunction
- metabolic acidosis
- nephrolithiasis
- seizures
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More about zonisamide
- zonisamide consumer information
- Compare alternatives
- Pricing & coupons
- Reviews (146)
- Drug images
- Side effects
- Dosage information
- During pregnancy
- Drug class: carbonic anhydrase inhibitor anticonvulsants
- Breastfeeding
- En español
Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Levetiracetam
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Lamictal
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Topiramate
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Diazepam
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Pregabalin
Pregabalin may be used to treat certain types of pain and used in combination with other ...
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
