Generic Name: riluzole (RIL ue zole)
Brand Name: Rilutek, Tiglutik
Dosage Forms: oral suspension (50 mg/10 mL); oral tablet (50 mg)
What is riluzole?
Riluzole is used to treat amyotrophic lateral sclerosis, also known as ALS or Lou Gehrig's disease.
Riluzole is not a cure for ALS, but it may delay progression of the disease and prolong your life.
Riluzole may also be used for purposes not listed in this medication guide.
Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use.
Before taking this medicine
You should not use riluzole if you are allergic to it.
Tell your doctor if you have ever had:
Riluzole may harm an unborn baby. Use effective birth control to prevent pregnancy, and tell your doctor if you become pregnant.
It may not be safe to breastfeed while using riluzole. Ask your doctor about any risk.
Riluzole is not approved for use by anyone younger than 18 years old.
How should I take riluzole?
Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.
Take riluzole on an empty stomach, at least 1 hour before or 2 hours after a meal.
Riluzole may also be given through a PEG feeding tube.
Read and carefully follow any Instructions for Use provided with your medicine. Ask your doctor or pharmacist if you do not understand these instructions.
Shake the oral suspension (liquid) before you measure a dose. Use the dosing syringe provided, or use a medicine dose-measuring device (not a kitchen spoon).
You will need frequent medical tests.
Store at room temperature away from moisture, heat, and light. Keep the liquid medicine upright and do not freeze. Throw away any unused liquid after 15 days.
What happens if I miss a dose?
Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.
What happens if I overdose?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.
Overdose symptoms may include drowsiness, confusion, problems with thinking or memory, coma, tremors, or blue lips or fingers.
What should I avoid while taking riluzole?
Avoid smoking. Smoking cigarettes may make riluzole less effective.
What are the riluzole side effects of riluzole?
Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Stop using riluzole and call your doctor at once if you have:
sudden chest pain, wheezing, feeling short of breath;
dry cough, or cough with mucus;
low white blood cell counts--fever, mouth sores, skin sores, sore throat; or
Side effects may be more likely to occur in people of Japanese descent.
Common side effects may include:
increased blood pressure;
numbness or tingling around your mouth;
stomach pain, nausea; or
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
What other drugs will affect riluzole?
Sometimes it is not safe to use certain medications at the same time. Some drugs can affect your blood levels of other drugs you take, which may increase side effects or make the medications less effective.
Riluzole can harm your liver, especially if you also use certain medicines for infections, high cholesterol, seizures, birth control, hormone replacement, or pain or arthritis (including Tylenol, Advil, and Aleve).
Other drugs may affect riluzole, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.
Frequently asked questions
More about riluzole
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- Drug class: miscellaneous central nervous system agents
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Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
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