Generic name: riluzole [ RIL-ue-zole ]
Brand names: Exservan, Rilutek, Tiglutik
Dosage forms: oral film (50 mg); oral suspension (50 mg/10 mL); oral tablet (50 mg)
Drug class: Miscellaneous central nervous system agents
What is riluzole?
Riluzole is used to treat amyotrophic lateral sclerosis, also known as ALS or Lou Gehrig's disease.
Riluzole is not a cure for ALS, but it may delay progression of the disease and prolong your life.
Riluzole may also be used for purposes not listed in this medication guide.
Use only as directed. Tell your doctor if you use other medicines or have other medical conditions or allergies.
Before taking this medicine
You should not use riluzole if you are allergic to it.
Tell your doctor if you have ever had:
Riluzole may harm an unborn baby. Use effective birth control to prevent pregnancy, and tell your doctor if you become pregnant.
Ask a doctor if it is safe to breastfeed while using riluzole.
Not approved for use by anyone younger than 18 years old.
How should I take riluzole?
Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.
Take riluzole on an empty stomach, at least 1 hour before or 2 hours after a meal.
Riluzole may also be given through a PEG feeding tube.
Read and follow all Instructions for Use. Ask your doctor or pharmacist if you need help.
Shake the oral suspension (liquid) before you measure a dose. Use the dosing syringe provided, or use a medicine dose-measuring device (not a kitchen spoon).
You will need frequent medical tests.
Store at room temperature away from moisture, heat, and light. Keep the liquid medicine upright and do not freeze. Throw away any unused liquid after 15 days.
What happens if I miss a dose?
Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.
What happens if I overdose?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.
Overdose symptoms may include drowsiness, confusion, problems with thinking or memory, coma, tremors, or blue lips or fingers.
What should I avoid while taking riluzole?
Avoid smoking. Smoking cigarettes may make riluzole less effective.
What are the riluzole side effects of riluzole?
Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Stop using riluzole and call your doctor at once if you have:
sudden chest pain, wheezing, feeling short of breath;
dry cough, or cough with mucus;
low white blood cell counts--fever, mouth sores, skin sores, sore throat; or
Side effects may be more likely to occur in people of Japanese descent.
Common side effects may include:
increased blood pressure;
numbness or tingling around your mouth;
stomach pain, nausea; or
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
What other drugs will affect riluzole?
Sometimes it is not safe to use certain medications at the same time. Some drugs can affect your blood levels of other drugs you take, which may increase side effects or make the medications less effective.
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Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
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