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Medications for Postpartum Depression

Other names: Depression, Postnatal; Depression, Postpartum; PDD; PND; Postnatal Depression

About Postpartum Depression

Postpartum depression is severe depression in a woman after she has given birth. It may occur soon after delivery or up to a year later. Most of the time, it occurs sometime in the first 4 weeks after delivery.

Drugs used to treat Postpartum Depression

The following list of medications are in some way related to, or used in the treatment of this condition.

Drug name Rating Reviews Activity ? Rx/OTC Pregnancy CSA Alcohol
Zoloft 8.3 42 reviews
Rx C N X

Generic name: sertraline systemic

Drug class: selective serotonin reuptake inhibitors

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

sertraline 8.3 55 reviews
Rx C N X

Generic name: sertraline systemic

Brand name:  Zoloft

Drug class: selective serotonin reuptake inhibitors

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Celexa 6.9 13 reviews
Rx C N X

Generic name: citalopram systemic

Drug class: selective serotonin reuptake inhibitors

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

Prozac 10 2 reviews
Rx C N X

Generic name: fluoxetine systemic

Drug class: selective serotonin reuptake inhibitors

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

citalopram 6.7 25 reviews
Rx C N X

Generic name: citalopram systemic

Brand name:  Celexa

Drug class: selective serotonin reuptake inhibitors

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Effexor XR 7.1 14 reviews
Rx C N X

Generic name: venlafaxine systemic

Drug class: serotonin-norepinephrine reuptake inhibitors

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

fluoxetine 10 3 reviews
Rx C N X

Generic name: fluoxetine systemic

Brand name:  Prozac

Drug class: selective serotonin reuptake inhibitors

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Paxil 5.9 8 reviews
Rx D N X

Generic name: paroxetine systemic

Drug class: selective serotonin reuptake inhibitors

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

venlafaxine 6.9 21 reviews
Rx C N X

Generic name: venlafaxine systemic

Brand names:  Effexor XR, Effexor

Drug class: serotonin-norepinephrine reuptake inhibitors

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Effexor 2.5 2 reviews
Rx C N X

Generic name: venlafaxine systemic

Drug class: serotonin-norepinephrine reuptake inhibitors

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

paroxetine 5.9 8 reviews
Rx D N X

Generic name: paroxetine systemic

Brand names:  Paxil, Paxil CR

Drug class: selective serotonin reuptake inhibitors

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Paxil CR Rate Add review
Rx D N X

Generic name: paroxetine systemic

Drug class: selective serotonin reuptake inhibitors

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

brexanolone Rate Add review
Rx 4 X

Generic name: brexanolone systemic

Brand name:  Zulresso

Drug class: miscellaneous antidepressants

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph

Zulresso Rate Add review
Rx 4 X

Generic name: brexanolone systemic

Drug class: miscellaneous antidepressants

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

Learn more about Postpartum Depression

IBM Watson Micromedex

Symptoms and treatments

Drugs.com Health Center

Mayo Clinic Reference

Legend

Rating For ratings, users were asked how effective they found the medicine while considering positive/adverse effects and ease of use (1 = not effective, 10 = most effective).
Activity Activity is based on recent site visitor activity relative to other medications in the list.
Rx Prescription Only.
OTC Over the Counter.
Rx/OTC Prescription or Over the Counter.
Off-label This medication may not be approved by the FDA for the treatment of this condition.
EUA An Emergency Use Authorization (EUA) allows the FDA to authorize unapproved medical products or unapproved uses of approved medical products to be used in a declared public health emergency when there are no adequate, approved, and available alternatives.
Pregnancy Category
A Adequate and well-controlled studies have failed to demonstrate a risk to the fetus in the first trimester of pregnancy (and there is no evidence of risk in later trimesters).
B Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women.
C Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
D There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
X Studies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use in pregnant women clearly outweigh potential benefits.
N FDA has not classified the drug.
Controlled Substances Act (CSA) Schedule
N Is not subject to the Controlled Substances Act.
1 Has a high potential for abuse. Has no currently accepted medical use in treatment in the United States. There is a lack of accepted safety for use under medical supervision.
2 Has a high potential for abuse. Has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse may lead to severe psychological or physical dependence.
3 Has a potential for abuse less than those in schedules 1 and 2. Has a currently accepted medical use in treatment in the United States. Abuse may lead to moderate or low physical dependence or high psychological dependence.
4 Has a low potential for abuse relative to those in schedule 3. It has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 3.
5 Has a low potential for abuse relative to those in schedule 4. Has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 4.
Alcohol
X Interacts with Alcohol.

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Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.