Zurzuvae Dosage
Generic name: ZURANOLONE 30mg
Dosage form: capsule
Drug class: Miscellaneous antidepressants
Medically reviewed by Drugs.com. Last updated on Nov 5, 2024.
Recommended Dosage
The recommended dosage of ZURZUVAE is 50 mg taken orally once daily in the evening for 14 days. Administer ZURZUVAE with fat-containing food (e.g., 400 to 1,000 calories, 25% to 50% fat). If patients experience CNS depressant effects within the 14-day period, consider reducing the dosage to 40 mg once daily in the evening within the 14-day period.
ZURZUVAE can be used alone or as an adjunct to oral antidepressant therapy.
The safety and effectiveness of ZURZUVAE use beyond 14 days in a single treatment course have not been established.
Recommended Dosage in Patients with Hepatic Impairment
The recommended dosage of ZURZUVAE in patients with severe hepatic impairment (Child-Pugh C) is 30 mg orally once daily in the evening for 14 days. The recommended dosage in patients with mild (Child-Pugh A) or moderate (Child-Pugh B) hepatic impairment is the same as those in patients with normal hepatic function.
Recommended Dosage in Patients with Renal Impairment
The recommended dosage of ZURZUVAE in patients with moderate or severe renal impairment (eGFR <60 mL/min/1.73 m2) is 30 mg orally once daily in the evening for 14 days.
The recommended dosage in patients with mild renal impairment (eGFR 60 to 89 mL/min/1.73 m2) is the same as those in patients with normal renal function.
Recommendations Regarding a Missed Dose
If a ZURZUVAE evening dose is missed, take the next dose at the regular time the following evening. Do not take extra capsules on the same day to make up for the missed dose. Continue taking ZURZUVAE once daily until the remainder of the 14-day treatment course is completed.
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