Celexa Dosage
Generic name: CITALOPRAM HYDROBROMIDE 10mg
Dosage form: tablets, film coated
Drug class: Selective serotonin reuptake inhibitors
Medically reviewed by Drugs.com. Last updated on Oct 9, 2023.
2.1 Recommended Dosage
Administer CELEXA once daily, with or without food, at an initial dosage of 20 mg once daily, with an increase to a maximum dosage of 40 mg once daily at an interval of no less than one week.
Dosages above 40 mg once daily are not recommended due to the risk of QT prolongation.
2.2 Screen for Bipolar Disorder Prior to Starting CELEXA
Prior to initiating treatment with CELEXA or another antidepressant, screen patients for a personal or family history of bipolar disorder, mania, or hypomania .
2.3 Recommended Dosage for Specific Populations
The maximum recommended dosage of CELEXA for patients who are greater than 60 years of age, patients with hepatic impairment, and for CYP2C19 poor metabolizers is 20 mg once daily.
2.4 Dosage Modifications with Concomitant Use of CYP2C19 Inhibitors
The maximum recommended dosage of CELEXA when used concomitantly with a CYP2C19 inhibitor is 20 mg once daily.
2.5 Switching Patients to or from a Monoamine Oxidase Inhibitor Antidepressant
At least 14 days must elapse between discontinuation of a monoamine oxidase inhibitor (MAOI) antidepressant and initiation of therapy with CELEXA. Conversely, at least 14 days must elapse after stopping CELEXA before starting an MAOI antidepressant.
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