Zepbound Interactions
There are 414 drugs known to interact with Zepbound (tirzepatide), along with 5 disease interactions, and 3 alcohol/food interactions. Of the total drug interactions, 15 are major, 398 are moderate, and 1 is minor.
- View all 414 medications that may interact with Zepbound
- View Zepbound alcohol/food interactions (3)
- View Zepbound disease interactions (5)
Most frequently checked interactions
View interaction reports for Zepbound (tirzepatide) and the medicines listed below.
- albuterol
- amlodipine
- aspirin
- atorvastatin
- Benadryl (diphenhydramine)
- bupropion
- buspirone
- cyclobenzaprine
- famotidine
- gabapentin
- hydrochlorothiazide
- hydroxyzine
- ibuprofen
- levothyroxine
- lisinopril
- losartan
- melatonin
- meloxicam
- metformin
- montelukast
- omeprazole
- pantoprazole
- prednisone
- propranolol
- rosuvastatin
- sertraline
- trazodone
- Vitamin B12 (cyanocobalamin)
- Vitamin D3 (cholecalciferol)
- Zyrtec (cetirizine)
Zepbound alcohol/food interactions
There are 3 alcohol/food interactions with Zepbound (tirzepatide).
Zepbound disease interactions
There are 5 disease interactions with Zepbound (tirzepatide) which include:
Report options
More about Zepbound (tirzepatide)
- Zepbound consumer information
- Compare alternatives
- Pricing & coupons
- Reviews (356)
- Drug images
- Latest FDA alerts (2)
- Side effects
- Dosage information
- During pregnancy
- Support group
- FDA approval history
- Drug class: GLP-1 Agonists (Incretin Mimetics)
- Breastfeeding
- En español
Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
