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Alli (orlistat) Drug Interactions

A total of 185 drugs are known to interact with Alli (orlistat).

  • 5 major drug interactions
  • 156 moderate drug interactions
  • 24 minor drug interactions

Show all medications in the database that may interact with Alli (orlistat).

Check for interactions

Type in a drug name to check for interactions with Alli (orlistat).

Most frequently checked interactions

View interaction reports for Alli (orlistat) and the medicines listed below.

  • clonazepam (Klonopin, Klonopin Wafer)
  • Cymbalta (duloxetine)
  • Fish Oil (omega-3 polyunsaturated fatty acids)
  • gabapentin (Neurontin, Gralise, Gabarone, Fanatrex)
  • garcinia cambogia
  • hydrochlorothiazide (HydroDIURIL, Microzide, Oretic, Esidrix, Ezide, Aquazide H, Hydro Par, Carozide, Diaqua, Loqua)
  • ibuprofen (Advil, Motrin, IBU, Children's Motrin, Proprinal, Advil Liqui-Gels, Ibu-8, Motrin IB, Motrin Childrens, Rufen, Childrens Ibuprofen Berry, IBU-200, Ibuprofen PMR, Advil Migraine, Ibu-Tab, Genpril, Menadol, Advil Children's, Midol Maximum Strength Cramp Formula, Motrin Migraine Pain, Addaprin, Motrin Infant Drops, NeoProfen, Caldolor, Motrin Pediatric, Haltran, Midol IB, Saleto-200, Q-Profen, Saleto-400, Saleto-600, Saleto-800, A-G Profen, Nuprin, Advil Junior Strength, Actiprofen, PediaCare Infants' IB Ibuprofen Pain Reliever/Fever Reducer, Ibu-4, PediaCare Children's IB Ibuprofen Pain Reliever/Fever Reducer, Ibu-6, Motrin Junior Strength, Help I Have An Aching Body, Children's ElixSure IB, Advil Infant's Concentrated Drops, Cap-Profen, Advil Film-Coated)
  • levothyroxine (Synthroid, Levoxyl, Tirosint, Levothroid, Eltroxin, Euthyrox, Unithroid, Levothyrox, Eutroxsig, Levo-T, Oroxine, L Thyroxine Roche, Levotabs, Novothyrox, Tirosint-Sol, Levotec, Evotrox)
  • Lipitor (atorvastatin)
  • lisinopril (Zestril, Prinivil, Qbrelis)
  • melatonin (Melatonin Time Release, SGard, Bio-Melatonin, Health Aid Melatonin, VesPro Melatonin)
  • metformin (Glucophage, Glumetza, Glucophage XR, Fortamet, Riomet)
  • multivitamin (Daflon, Metanx, Neurobion, Vitamins, Theragran, Vitamin B Complex 100, Cerefolin NAC, Cerefolin, Rena-Vite, Folbic, Foltx, Estroven, Nephro-Vite, Lipoflavonoid, Folbee, Foltanx, Thera, Super B Complex, MVI Adult, Nephrocaps, PoDiaPN, Folic Acid XTRA, Tab-A-Vite, Cod Liver Oil Mint, B Complex 100, Triphrocaps, FaBB, Nufola, Nephro-Vite Rx, Cod Liver Oil, Multi Vitamin+, Rheumate, Renal Caps, Essentiale, Berocca, Daily Vite, Rena-Vite Rx, Xyzbac, Lysiplex, Flintstones Multivitamins, Surbex, Super B-50, Fletanol, Infuvite, Infuvite Pediatric, Folcaps, Folinic-Plus, StressTabs, Reno Caps, Surbex with C, Folika-T, Apetigen, Stress Formula, B Complex 50, Cernevit, Vitamin Daily Liquid, Topfit Vitamin B Complex, Vitamin B Compound Strong, Nephronex, Folgard RX, One-A-Day Men's Health Formula, Folplex, Nephplex Rx, Metafolbic Plus, Virt-Caps, Therems, Daily Multiple Vitamins, Childrens Chewable Multivitamins, Vitacirc-B, One-A-Day Essentials, Essential Balance, Flintstones with C Multivitamins, Stress B with C, Theravite, Thera-Plus, High Potency B Complex with B12 and C, Super B-100 TD, L-methylfolate Ca, Me-Cbl NAC, Theragenerix, Apetex, Folastin, Topfit Vitamin B Complex Forte, L-Methyl-B6-B12, Jetepar, Vitamin A and D Concentrate, Centrum 8400, Foltabs 800, Menopause Relief with Lifenol, Daily-Vite Men's Formula, Biotin Forte, Vimar, B 100 Complex, Vol-Care Rx, Folbic RF, Foltanx RF, Mebolex, Mebolic, B-Plex, Vitaplex, Metafolbic, Stress-600, Thera-Tabs, Vi-Daylin, Poly-Vi-Sol, Watkins Harvest, Balanced B-100, B-Stress, B-Scorbic, Bee with C, Balanced B-50, Nat-Rul B-125, Balanced B-150, Unicap Capsule, Unicap Jr, Unicap, Optilets-500, Super Plenamins, Vitamins for Hair, Vi-Daylin Chewable, Folast, Enfolast, Sunkist Child Chewable with C, Enfolast-N, Sunkist Child Chewable, Poly-Vi-Sol Chewable, Neurpath-B, Fruity Chew, Triphro, Poly-Vit Chew, Vita-Respa, Chewable-Vite, Bugs Bunny with Extra C, Geravine, Bounty Bear Vitamins, Garfield Vitamins, Vi-Daylin Drops, Poly-Vi-Sol Drops, Baby Vitamin Drop, Vita Drop, Poly Vit Drops, MVC SDV, Glutofac, Allbee-C, Vitabee with C, High Potency B+C, Av-VITE FB, Farbee with C, Mynephron, Renatabs, Tri-Vitamin, DEKAs Essential, Vitamin B-50, Vitamin B-100, D-400 international units, Vitamin B-100 T/R, Hexavitamin, Celebrate B-12, Kenwood Therapeutic, Oncovite, Glycogenics, Beminal-500, Tri-Vit Drops, Flintstones Toddler, One Tab Daily, Vitamin C, E, and Rose Hips, Scotts Emulsion, Stress Formula 600, Tri-Vit, Mega B, Apatate, T-Vites, Hylavite, High B Complex, L-methylfolate Ca, P-5-P, Me-Cbl, Prostate 2.4, MTX Support, Cardiotek, Beminal, Beminal with C Fortis, Full Spectrum B with C, Bugs Bunny Multiple Vitamins, Allbee with C, Prevital, Surbex Filmtab, Tender Age Vitamin ADC, Folgard Rx 2.2, Cernevit-12, SeroSyn, Diatx, Vitamin A, D, One-A-Day 50+, Thex Forte, Metafolbic Plus RF, Dosoquin, Protegra Cardio, Virt-Vite Plus, K2 Plus D3, Renaphro, Virt-Gard, Dialyvite Rx, L-Methyl-MC, Levomefolate Calcium-Algal Powder, VP-Vite Rx, Vesselvite, Folbee Plus, Combgen, Abidec, Unichem Multivitamin, Health Aid Multivitamin, AllanTex, One Daily Multi-Essential, Larobec, Foltrate, Cardiotek Rx, Folbalin Plus, Dialyvite 800, Folbalin, Multi-Delyn, Multi Vits with Beta Carotene, Foleve Plus, Folnate, Folnate Plus, B-Complex with B-12, Foleve, Hair, Skin, & Nails Gummies, Folamin, DexFol, Equaline One Daily Essential, Av-VITE FB Forte, Folmor, Zycose, Vigomar Forte, Allbee Plus, Triveen-CF, Nature's Bounty Hair Skin & Nails, Total B with C, Methaver, GNC Women's Hair, Skin & Nails Formula, Folbee AR, NuFol, Co-Veratrol, Methazel, Dyzbac, Mynephrocaps, Omega Q Plus, Acnepril, Super Theravite-M, Primaplex, Becomject-100, Poly-Vita Drops, MVI-12, B-Ject 100, L-Methyl-MC NAC, Therobec, Formula B, Tri-Vi-Sol, TL Gard, Vi-Daylin ADC, Lipogen, Nephrocaps QT, Virt-Vite, Lipotriad, Virt-Vite Forte, Folplex 2.2, Cholinoid, Tri-Vita Drops, Liponol, Bee-Comp with C, Cholidase, Vita-Plus G, Rovin-CF, Cota-B-Plex, 1000 BC, Neurodep, Neuroforte-Six, MVI Pediatric, B-Plex Plus, Nephrolan Rx, Ivites Rx, Zymacap, Dayalets, Sigtab, Allbee-C 800, Cefol, B-Complex SR, Protegra, Wellesse Sugar Free Childrens Multivitamin Gummies, Alz-Nac, Sesame St Vitamins with Extra C, Surbex-T, Male Formula, Superplex-T, Vi-Stress, T-BMP, Animal Shape Vitamins, B-50 Complex, Niva-Fol)
  • Nexium (esomeprazole)
  • omeprazole (Prilosec, Prilosec OTC, Zegerid (Original Formulation), Omesec)
  • phentermine (Adipex-P, Lomaira, Fastin, Ionamin, T-Diet, Suprenza, Oby-Cap, Teramine, Obenix, Atti-Plex P, Pro-Fast HS, Phentercot, Phentride, Obephen, Panshape M, Pro-Fast SR, Zantryl, Oby-Trim, Pro-Fast SA, Teramine ER)
  • prednisone (Deltasone, Rayos, Sterapred, Prednicot, Sterapred DS, Meticorten, Orasone, Liquid Pred, Prednicen-M)
  • simvastatin (Zocor, FloLipid)
  • Synthroid (levothyroxine)
  • tramadol (Ultram, Tramadol Hydrochloride ER, Tramal, Ultram ER, ConZip, Zydol, Tramal SR, GenRx Tramadol, Zamadol, Ryzolt, Tramedo, Larapam SR, Tramahexal SR, Tramahexal, Zydol XL, Rybix ODT, Ultram ODT)
  • trazodone (Desyrel, Oleptro, Desyrel Dividose)
  • Vitamin B12 (cyanocobalamin)
  • Vitamin D3 (cholecalciferol)

Alli (orlistat) alcohol/food interactions

There is 1 alcohol/food interaction with Alli (orlistat)

Alli (orlistat) disease interactions

There are 4 disease interactions with Alli (orlistat) which include:

Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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