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Methamphetamine Side Effects

For the Consumer

Applies to methamphetamine: oral tablet, oral tablet extended release

Along with its needed effects, methamphetamine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking methamphetamine:

Rare
  • Agitation
  • delusions
  • hallucinations
Incidence not known
  • Blurred vision
  • chest discomfort or pain
  • dark-colored urine
  • difficulty breathing
  • dizziness
  • faintness
  • false or unusual sense of wellbeing
  • fast, pounding, or irregular heartbeat or pulse
  • fever
  • headache
  • muscle cramps or spasms
  • muscle pain or stiffness
  • pounding in the ears
  • restlessness
  • shakiness in the legs, arms, hands, or feet
  • swelling of the feet or lower legs
  • trembling or shaking of the hands or feet
  • trouble sleeping
  • twitching, twisting, or uncontrolled repetitive movements of the tongue, lips, face, arms, or legs
  • uncontrolled vocal outbursts and tics
  • unusual tiredness or weakness

Some side effects of methamphetamine may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Incidence not known
  • Bad, unusual, or unpleasant (after) taste
  • change in taste
  • constipation
  • decreased interest in sexual intercourse
  • dry mouth
  • hives or welts, itching, or skin rash
  • inability to have or keep an erection
  • indigestion
  • loss in sexual ability, desire, drive, or performance
  • passing of gas
  • redness of the skin
  • weight loss

For Healthcare Professionals

Applies to methamphetamine: oral tablet, oral tablet extended release

Cardiovascular

Frequency not reported: Elevated blood pressure, tachycardia, palpitation, fatal cardiorespiratory arrest
Postmarketing reports: Peripheral vasculopathy[Ref]

Musculoskeletal

Frequency not reported: Rhabdomyolysis, growth suppression[Ref]

Psychiatric

Rare (less than 0.1%): Psychotic episodes
Frequency not reported: Dysphoria, euphoria, insomnia, restlessness[Ref]

Nervous system

Frequency not reported: Dizziness, overstimulation, tremor, headache, exacerbation of motor/phonic tics and Tourette's syndrome[Ref]

Gastrointestinal

Frequency not reported: Diarrhea, constipation, dry mouth, unpleasant taste, other GI disturbances[Ref]

Endocrine

Frequency not reported: Impotence, libido changes, frequent or prolonged erections[Ref]

Hypersensitivity

Frequency not reported: Urticaria[Ref]

References

1. "Product Information. Desoxyn (methamphetamine)" Abbott Pharmaceutical, Abbott Park, IL.

Some side effects of methamphetamine may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.

Disclaimer: Every effort has been made to ensure that the information provided is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate safety, effectiveness, or appropriateness for any given patient. Drugs.com does not assume any responsibility for any aspect of healthcare administered with the aid of materials provided. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the substances you are taking, check with your doctor, nurse, or pharmacist.

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