Skip to Content

Qsymia (phentermine / topiramate) Drug Interactions

A total of 822 drugs are known to interact with Qsymia (phentermine / topiramate).

  • 418 major drug interactions
  • 400 moderate drug interactions
  • 4 minor drug interactions

Show all medications in the database that may interact with Qsymia (phentermine / topiramate).

Check for interactions

Type in a drug name to check for interactions with Qsymia (phentermine / topiramate).

Most frequently checked interactions

View interaction reports for Qsymia (phentermine / topiramate) and the medicines listed below.

  • Adderall (amphetamine / dextroamphetamine)
  • Aleve (naproxen)
  • Belviq (lorcaserin)
  • bupropion (Wellbutrin, Wellbutrin XL, Wellbutrin SR, Zyban, Buproban, Aplenzin, Budeprion, Forfivo XL, Budeprion SR, Budeprion XL)
  • clonazepam (Klonopin, Klonopin Wafer)
  • Cymbalta (duloxetine)
  • Effexor (venlafaxine)
  • fluoxetine (Prozac, Prozac Weekly, Sarafem, Selfemra, Rapiflux)
  • gabapentin (Neurontin, Gralise, Gabarone, Fanatrex)
  • hydrochlorothiazide (HydroDIURIL, Microzide, Esidrix, Oretic, Aquazide H, Diaqua, Hydro Par, Ezide, Carozide, Loqua)
  • ibuprofen (Advil, Motrin, IBU, Advil Liqui-Gels, Motrin IB, Proprinal, Advil Children's, Caldolor, Children's Motrin, Childrens Ibuprofen Berry, Motrin Childrens, Rufen, Ibuprofen PMR, Ibu-8, Motrin Pediatric, Menadol, Nuprin, Advil Junior Strength, Midol Maximum Strength Cramp Formula, Motrin Migraine Pain, Advil Migraine, PediaCare Children's IB Ibuprofen Pain Reliever/Fever Reducer, Ibu-6, NeoProfen, Ibu-Tab, Genpril, Haltran, IBU-200, Midol IB, Saleto-200, Q-Profen, Saleto-400, Saleto-600, Saleto-800, A-G Profen, Actiprofen, Addaprin, PediaCare Infants' IB Ibuprofen Pain Reliever/Fever Reducer, Ibu-4, Motrin Junior Strength, Motrin Infant Drops, Help I Have An Aching Body, Children's ElixSure IB, Advil Infant's Concentrated Drops, Cap-Profen, Advil Film-Coated)
  • levothyroxine (Synthroid, Levoxyl, Tirosint, Levothroid, Eltroxin, Levothyrox, Euthyrox, Unithroid, L Thyroxine Roche, Levo-T, Oroxine, Eutroxsig, Novothyrox, Tirosint-Sol, Levotabs, Levotec, Evotrox)
  • Lexapro (escitalopram)
  • lisinopril (Zestril, Prinivil, Qbrelis)
  • losartan (Cozaar)
  • meloxicam (Mobic, Vivlodex, Qmiiz ODT)
  • metformin (Glucophage, Glumetza, Glucophage XR, Fortamet, Riomet)
  • Mucinex (guaifenesin)
  • omeprazole (Prilosec, Prilosec OTC, Zegerid (Original Formulation), Omesec)
  • Paxil (paroxetine)
  • phentermine (Adipex-P, Lomaira, Fastin, Suprenza, Ionamin, Teramine, Obenix, Atti-Plex P, Pro-Fast HS, Phentercot, Oby-Cap, Phentride, Obephen, Panshape M, Pro-Fast SR, T-Diet, Zantryl, Oby-Trim, Pro-Fast SA, Teramine ER)
  • prednisone (Deltasone, Rayos, Sterapred, Prednicot, Meticorten, Sterapred DS, Liquid Pred, Orasone, Prednicen-M)
  • Prozac (fluoxetine)
  • Synthroid (levothyroxine)
  • tramadol (Ultram, Tramadol Hydrochloride ER, Tramal, Ultram ER, Zydol, Tramahexal, Ryzolt, Tramal SR, ConZip, Larapam SR, GenRx Tramadol, Tramedo, Zamadol, Tramahexal SR, Zydol XL, Rybix ODT, Ultram ODT)
  • trazodone (Desyrel, Oleptro, Desyrel Dividose)
  • Vitamin B12 (cyanocobalamin)
  • Vitamin D3 (cholecalciferol)
  • Wellbutrin (bupropion)
  • wine
  • Xanax (alprazolam)
  • Zoloft (sertraline)

Qsymia (phentermine / topiramate) alcohol/food interactions

There are 3 alcohol/food interactions with Qsymia (phentermine / topiramate)

Qsymia (phentermine / topiramate) disease interactions

There are 24 disease interactions with Qsymia (phentermine / topiramate) which include:

Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Hide