Generic Name: lorcaserin (lor KAS er in)
Brand Name: Belviq
What is lorcaserin?
Lorcaserin affects chemicals in the brain that affect appetite.
Lorcaserin is used together with diet and exercise to treat obesity
Lorcaserin is sometimes used to treat obesity that may be related to diabetes, high cholesterol, or high blood pressure.
Lorcaserin will not treat any underlying condition you have (such as heart disease, diabetes, high blood pressure). Keep taking any other medications your doctor has prescribed to treat these conditions.
Lorcaserin may also be used for purposes not listed in this medication guide.
What is the most important information I should know about lorcaserin?
You should not use lorcaserin if you are allergic to it, or if you are pregnant.
Before you take lorcaserin, tell your doctor if you have diabetes, congestive heart failure, a heart valve disorder, sickle cell anemia, leukemia or myeloma, kidney or liver disease, or a physical deformity of the penis (such as Peyronie's disease).
Weight loss during pregnancy can harm an unborn baby, even if you are overweight. Do not use lorcaserin if you are pregnant.
You should not breast-feed while you are using lorcaserin.
Lorcaserin may be habit-forming and should be used only by the person for whom it was prescribed. Keep the medication in a secure place where others cannot get to it.
Do not take this medication in larger or smaller amounts or for longer than recommended
Tell your doctor if you do not lose at least 5% of your starting weight after taking the medication for 12 weeks.
Lorcaserin is only part of a complete program of treatment that also includes diet, exercise, weight control, and possibly testing your blood sugar.
There are many other drugs that can interact with lorcaserin. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.
What should I discuss with my healthcare provider before taking lorcaserin?
You should not use lorcaserin if you are allergic to it, or if you are pregnant.
To make sure you can safely take lorcaserin, tell your doctor if you have any of these other conditions:
congestive heart failure;
a heart valve disorder;
sickle cell anemia;
leukemia or myeloma;
kidney or liver disease; or
a physical deformity of the penis (such as Peyronie's disease).
Lorcaserin may be habit forming and should be used only by the person for whom it was prescribed. Never share lorcaserin with another person, especially someone with a history of drug abuse or addiction. Keep the medication in a place where others cannot get to it.
FDA pregnancy category X. Weight loss during pregnancy can harm an unborn baby, even if you are overweight. Do not use lorcaserin if you are pregnant. Tell your doctor right away if you become pregnant during treatment.
It is not known whether lorcaserin passes into breast milk or if it could harm a nursing baby. You should not breast-feed while you are using lorcaserin.
Do not give this medication to anyone under 18 years old without medical advice.
How should I take lorcaserin?
Take exactly as prescribed by your doctor. Do not take in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label.
The usual dose of lorcaserin is 1 tablet 2 times each day. Follow your doctor's instructions.
You may take lorcaserin with or without food.
You should lose at least 5% of your starting weight during the first 12 weeks of taking lorcaserin and eating a low calorie diet. Tell your doctor if you do not lose at least 5% of your starting weight after taking the medication for 12 weeks.
Lorcaserin is only part of a complete program of treatment that also includes diet, exercise, weight control, and possibly testing your blood sugar. Follow your diet, medication, and exercise routines very closely.
Store at room temperature away from moisture and heat.
Keep track of the amount of medicine used from each new bottle. Lorcaserin is a drug of abuse and you should be aware if anyone is using your medicine improperly or without a prescription.
Do not share lorcaserin with another person. Keep the medication in a place where others cannot get to it.
What happens if I miss a dose?
Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.
What happens if I overdose?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.
Overdose symptoms may include severe forms of some of the side effects listed in this medication guide.
What should I avoid while taking lorcaserin?
This medication may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert.
Do not take any other prescription or over-the-counter weight-loss products without your doctor's advice.
Avoid taking cough and cold or allergy medications while taking lorcaserin.
Lorcaserin side effects
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Stop using lorcaserin and call your doctor at once if you have a serious side effect such as:
unusual thoughts or behavior, feelings of extreme happiness or sadness;
feelings of standing next to yourself or being outside of your body;
thoughts of suicide or hurting yourself;
agitation, hallucinations, fever, rapid heart rate, overactive reflexes, nausea, vomiting, diarrhea, loss of coordination, fainting;
very stiff (rigid) muscles, high fever, sweating, confusion, fast or uneven heartbeats, tremors, feeling like you might pass out;
trouble breathing, slow heart rate;
feeling short of breath, even with mild exertion;
swelling in your hands or feet;
pale skin, feeling light-headed or short of breath, trouble concentrating;
body aches, flu symptoms, sores in your mouth and throat;
low blood sugar (headache, hunger, weakness, sweating, confusion, irritability, dizziness, or feeling jittery);
breast swelling (in women or men), nipple discharge; or
penis erection lasting longer than 4 hours.
Less serious side effects may include:
dizziness, drowsiness, feeling tired;
dry mouth, cough; or
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
See also: Side effects (in more detail)
Lorcaserin dosing information
Usual Adult Dose for Weight Loss:
10 mg orally twice per day
Comments: Response to therapy should be evaluated by week 12. If a patient has not lost at least 5% of baseline body weight, discontinue this drug as it is unlikely the patient will achieve and sustain clinically meaningful weight loss with continued treatment.
Use: Adjunct to a reduced-calorie diet and increased physical activity for chronic weight management in patients with an initial body mass index (BMI) of 30 kg/m2 or greater (obese) OR 27 kg/m2 or greater (overweight) in the presence of at least one weight-related comorbidity such as hypertension, type 2 diabetes mellitus, or dyslipidemia.
What other drugs will affect lorcaserin?
Tell your doctor about all other medicines you use, especially:
cold or cough medicine that contains dextromethorphan (a cough suppressant);
erectile dysfunction medicine such as sildenafil (Viagra), avanafil (Stendra), tadalafil (Cialis, Adcirca), or vardenafil (Levitra, Staxyn);
heart or blood pressure medication;
insulin or oral diabetes medications;
medicine to treat a psychiatric disorder;
narcotic pain medication;
St. John's wort;
tryptophan (also called L-tryptophan);
an MAO inhibitor such as furazolidone (Furoxone), isocarboxazid (Marplan), linezolid (Zyvox), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam, Zelapar), or tranylcypromine (Parnate);
an SNRI antidepressant such as duloxetine (Cymbalta) or venlafaxine (Effexor);
an SSRI antidepressant such as citalopram (Celexa), escitalopram (Lexapro), fluoxetine (Prozac, Rapiflux, Sarafem, Selfemra, Symbyax), fluvoxamine (Luvox), paroxetine (Paxil, Pexeva), sertraline (Zoloft), or vilazodone (Viibryd);
other antidepressants such as bupropion (Wellbutrin, Zyban) or trazodone (Desyrel, Oleptro); or
migraine headache medicine such as almotriptan (Axert), eletriptan (Relpax), frovatriptan (Frova), naratriptan (Amerge), rizatriptan (Maxalt), sumatriptan (Imitrex, Treximet) or zolmitriptan (Zomig).
There may be other drugs that can interact with lorcaserin. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.
More about lorcaserin
- Other brands: Belviq
Related treatment guides
Where can I get more information?
- Your pharmacist can provide more information about lorcaserin.
- Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
- Disclaimer: Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.
Copyright 1996-2012 Cerner Multum, Inc. Version: 1.01.
Date modified: October 14, 2016
Last reviewed: August 14, 2012