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Lorcaserin Dosage

Applies to the following strengths: 10 mg; 20 mg

Usual Adult Dose for:

Additional dosage information:

Usual Adult Dose for Weight Loss

10 mg orally twice per day

Comments: Response to therapy should be evaluated by week 12. If a patient has not lost at least 5% of baseline body weight, discontinue this drug as it is unlikely the patient will achieve and sustain clinically meaningful weight loss with continued treatment.

Use: Adjunct to a reduced-calorie diet and increased physical activity for chronic weight management in patients with an initial body mass index (BMI) of 30 kg/m2 or greater (obese) OR 27 kg/m2 or greater (overweight) in the presence of at least one weight-related comorbidity such as hypertension, type 2 diabetes mellitus, or dyslipidemia.

Renal Dose Adjustments

Liver Dose Adjustments


Safety and efficacy have not been established in patients younger than 18 years.

Consult WARNINGS section for additional precautions.

US Controlled Substance: Schedule IV


Other Comments

Administration Advice:


Endocrine: Blood glucose levels (prior to and during treatment in type 2 diabetic patients), prolactin (when prolactin excess is suspected)
Hematologic: CBC (periodically during treatment)
Nervous: Serotonin syndrome/Neuroleptic Malignant Syndrome-like signs and symptoms
Psychiatric: Depression, suicidal thoughts or behavior, unusual changes in mood or behavior

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.