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Canagliflozin use while Breastfeeding

Drugs containing Canagliflozin: Invokana, Invokamet, Invokamet XR

Medically reviewed by Drugs.com. Last updated on Apr 22, 2020.

Canagliflozin Levels and Effects while Breastfeeding

Summary of Use during Lactation

No information is available on the clinical use of canagliflozin during breastfeeding. Canagliflozin is is an uncharged molecule that is 99% protein bound in plasma, so it is unlikely to pass into breastmilk in clinically important amounts. The manufacturer does not recommend canagliflozin during breastfeeding because of a theoretical risk to the infant's developing kidney. An alternate drug may be preferred, especially while nursing a newborn or preterm infant.

Drug Levels

Maternal Levels. Relevant published information was not found as of the revision date.

Infant Levels. Relevant published information was not found as of the revision date

Effects in Breastfed Infants

Relevant published information was not found as of the revision date.

Effects on Lactation and Breastmilk

Relevant published information was not found as of the revision date.

Alternate Drugs to Consider

Acarbose, Glipizide, Glyburide, Insulin, Metformin, Miglitol

Substance Identification

Substance Name

Canagliflozin

CAS Registry Number

928672-86-0

Drug Class

  • Breast Feeding
  • Lactation
  • Hypoglycemic Agents
  • Sodium-Glucose Cotransporter 2 Inhibitors
  • SGLT2 Inhibitors

Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. The U.S. government does not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.