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What is the connection between the endocrine system and osteoporosis?

Medically reviewed by Last updated on Sep 20, 2022.

Official answer


Disorders of the endocrine system, such as hyperthyroidism, hypogonadism, growth hormone deficiency, and Cushing's syndrome frequently cause secondary osteoporosis.

Your endocrine system is a collection of glands that all produce hormones. It is responsible for ensuring good growth and development, regulating your metabolism, maintaining tissue and sexual function, supporting reproduction, and assisting sleep and mood, among other things.

Common endocrine disorders include diabetes and high thyroid levels (hyperthyroidism). These disorders cause osteoporosis because hormones that are needed to ensure healthy bone growth and development are compromised. A lack of certain hormones accelerates bone loss and increases fracture risk. Once these disorders have been identified and treated, bone density often increases.

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