Glipizide for Type 2 Diabetes User Reviews

• Lef...
• June 24, 2020

"I have type 2 diabetes; last year my HbA1c was 6.7. I was started on metformin and I had loose stools, liver problems and it wasn't even doing a great job for BG. I was then started on glipizide and I have no side effects and now HbA1c is 5.8"

• hap...
• August 19, 2009

Glipizide "I have taken it for over 10 years and I have had excellent results, and I am still taking the amount that I was started on, and my readings average 95. If you can beat that with another medicine, please let me know what it is."

• Ips...
• Taken for 1 to 6 months
• February 20, 2019

Glipizide "When I first started taking Glipizide-ER 5mg along with Trulicity once a week, also metformin 1000mg in the a.m. and 1000 mg at night. My blood sugars (BS) were dropping to 100-110. I also have insulin as needed on a sliding scale. I refilled my medicine, but maybe from a different manufacturer, my BS is reading 195-255. I'm constipated, moody as heck, dizzy in the morning. I bounce off the walls like a pinball machine, not to mention that I have gained a lot of weight. I have not changed my diet, not much exercise because I feel like rubbish all the time. Tonight I threw the medicine in the trash. It's bad stuff with too many side effects."

• Ski...
• Taken for 1 to 2 years
• April 16, 2017

"I got the shock of my life when I had blood work done and my sugar read in the 8.0 range. I received a call from the ER telling me I had to come in immediately for an insulin shot. I almost ran there. I went on Glipizide 5 mg., taken twice a day. I was not happy. I knew my weight had a lot to do with it, so I went on a diet. I went from 180 to 100 pounds. My doctor also put me on Metformin. All that did was make me vomit. Today, I control my sugar levels by diet alone. My doctor asks me about every six months if I would be willing to go back on the Metformin. 'No thanks. Vomiting is not my favorite activity. Today I am able to keep my A1c around 6.0-6.1. If I can do it so can you. Lose the weight."

• Nee...
• Taken for 5 to 10 years
• May 7, 2018

"I was given this medication many years ago when a doctor told me I was pre-diabetic. In the end, it was a wrong diagnosis, and it ruined my life. I became hypoglycemic, and so today I continue to suffer. Never, ever take any kind of medication without research. Now, as a senior citizen, I find that we are just guinea pigs for the pharmaceutical companies. Always check what Europeans use and will not use. In the United States, we use GMO’s in our foods, and our children are at risk. Be very aware of the dangers with autism on the rise, cancer in all of us. Stay away from new medications that have been on the market for less than 10 years."

• Get...
• Taken for less than 1 month
• June 16, 2020

"About six months ago, my doctor added glipizide to my existing regimen of Janumet 50/1000. While on glipizide, my blood pressure skyrocketed from 117/79 to 170/99 -- I still had the same healthy eating habits, same 5-day/wk workouts. My blood pressure became such a problem that my doctor urged me visit a cardiologist who then tried to add a blood pressure medication to list of meds. So, my most recent check up was visit a few days ago and my A1C was low enough that I insisted that we nix the glipizide. The very next day my blood pressure was back to 115/75."

• SDe...
• September 8, 2015

Glipizide "I started taking Glipizide ER initially with instructions to take it only if my blood glucose level was 180 or higher. I did not have to take it every day, but took it several times a week. Then I was started having a hard time controlling my daily glucose levels. My Hg A1c was higher, so the instructions were changed to 2 in the a.m. and 1 at night. I purchased the medication from a different source and it was a larger pill with now Glipazide XL instead of ER. I have experienced a number of side effects and feel worse with it than before I started taking it. The longer I have taken it the worse I feel. I feel drugged, want to sleep all the time, have a slight headache, more thirsty, constipation on occasion, dry eyes, and more. Yuck!"

• Anonymous
• June 30, 2008

Glipizide "I've been taking glipizide for two weeks. It is effective in lowering blood sugar and helps with postprandial spikes. It works fast, sometimes too fast, and has forced me to modify the timing and quantity of my meals."

• moz...
• November 3, 2011

Glipizide "I have taken Glipizide and Glipizide XL in conjunction with metformin for a number of years with no side effects. Anyone taking Glipizide (not XL) should be aware that blood sugar levels can plummet quickly and that dosage timing may need to be readjusted. With Glipizide XL, I have not experienced these fluctuations; however, the positive control appears to take effect much slower as this is a time-released form."

• Dan...
• Taken for 1 to 2 years
• October 9, 2018

"Glipizide works very well in lowering my blood sugar, but I gained a lot of weight. I thought it was due to my normal body changes until I started feeling terrible with this new big body. I asked my doctor about it, and he changed my medicine. I had gained 60 pounds in a year! When I stopped glipizide, I lost 20 pounds in the first month, and I'm still losing more. No more glipizide. It is not for me."

• Lon...
• Taken for 5 to 10 years
• March 4, 2013

Glipizide "I have used Glipizide XL for about 6 years now as a secondary medicine. Glipizide helps to keep my blood sugar numbers within range and keeps me from having to use insulin as much as I would without it, which is a good thing. I haven't had any side effects from the Glipizide at all. I'm very happy with this medication."

• CSm...
• Taken for less than 1 month
• October 23, 2014

"I was originally on Metformin 500mg. It got to a point where my A1C was going up so my dr put me on 1000mg (1x in the morning and 1x with dinner). My stomach couldn't handle it. My blood sugar levels were up and down. So I asked my dr if I could try something else. She put me on 2.5mg Glipizide ER and I feel so much better on it! I don't have the stomach issues and my blood sugar levels are lower and more stable. I'm glad I switched to Glipizide! I won't know my A1C until December but I expect it to be much better."

• Bax...
• Taken for 1 to 6 months
• June 18, 2019

Glipizide "My Dr. insisted I switch to Glipizide XL from glyburide. Well, this drug is NOT working at all for me, even at an increased dosage. My fasting glucose readings are 100 to 150 points higher than when I was on glyburide. But try telling and convincing a Dr. they're wrong."

• Meg...
• February 27, 2021

"I have been taking metformin, maximum dose for 8 years. Not working to bring down BS. Doctor put me on glipizide 5 mg in AM & PM. Not helping with BS control at all. Horrible side effects: dizziness, nausea, sore throat, cold symptoms, drowsiness."

• tam...
• May 28, 2008

"This drug has been great at bringing down my blood sugar levels and my A1C to acceptable levels in the 6 months I've been taking it (blood glucose ranges from 90-130 instead of 180-240, and A1C is 6.5 instead of 8.5)."

• Amd...
• Taken for 1 to 6 months
• June 25, 2019

"I was afraid to take glipizide because of weight gain. I’ve had no issues, and with effort, lost weight. It is fast-acting, so I take it before breakfast. No issues of too low glucose levels. Although depending on my numbers in the AM, I may only take a half pill instead of a whole 10 mg."

• Way...
• Taken for 1 to 2 years
• January 18, 2019

Glipizide "Took this med for diabetes for almost two years. I found that it contributed to fungal infections in genital areas. This was not listed as a side effect. After I stopped taking it, I no longer have this condition. It also caused sudden drops in my glucose levels."

• D2C...
• April 5, 2015

"Type 2. Active mom, 47, work, dance, sing, travel. 1000mg metformin twice a day, readings with Tradjenta between 140-230. Another doctor recommended yesterday to try Glipizide for 30 days, this morning a surprising 104. Feeling well."

• Mar...
• Taken for less than 1 month
• April 14, 2017

"Four years ago, I tried Metformin for my type 2 diabetes and had a horrific reaction: severe fainting, stomach pains, diarrhea, cramps, and I discontinued it. I tried a second time a few weeks later and had the same horrific reaction. This week, I started Glipizide, and in five days, I see a drop in my insulin to 115 from 346 at the start of the week. NO pains, cramps, diarrhea, and I can't believe it. It feels like a miracle after my Metformin experience."

• Anonymous
• April 10, 2012

"Blood sugar was stuck at 150 to 160 with no change for a while. A1C edging up to critical level. Within five days, it was within 110, and within seven days under 100. Side effects were no worse than Metformin alone."

• sug...
• Taken for 1 to 2 years
• February 7, 2019

Glipizide "I was originally on metformin 500 mg once daily when my A1C went to 7%. This didn't help, so my doctor added glipizide 5 mg once daily to my regimen. Both my sugars and A1C did not come down. Then again, I didn't change my eating habits or start exercising (but I am tall and thin, no weight problem here). After too much GI trouble, I stopped taking the metformin and told my doctor I'd never take it again. So, he upped my glipizide to ER 10 mg once daily. After changing my diet pretty dramatically (cut out refined sugars and carb intake), my sugars came down. However, now I'm having quite a few hypoglycemic attacks. Scary ones, like with a BS of 31. And I live alone, so that's worrying me now. Maybe my adjusted diet has resulted in me not needing 10 mg but maybe 5 mg daily again? It's kind of scary, though. I moved, so I have to find new doctors and get new blood work, so I'm hoping to hang in there and then learn possibly to not be so extreme in my eating and if the dose should go down."

• Bal...
• Taken for 1 to 6 months
• June 5, 2019

"Was taken off of 2000 mg of Metformin, which was controlling my diabetes well due to kidney failure. Placed on Glipizide 5 mg XR. Well, my blood sugars SOARED, regardless of what I've eaten. Almost no carbs eaten in the meal? I am looking at a 2-hour # in the 200's. I get no nighttime support with this med and have seen my morning sugars rise to the 180-190 range. I emailed my doc with the PDF of a month's worth of readings (4x a day), and she added a 500 mg Metformin back to nighttime. I go back in a week to have a blood test for kidney function, and I hope we can go back to Metformin because this med is useless for me. Oh, and every once in a while, I get the random drop - down to the 70's. No rhyme or reason to it. I had to start carrying glucose tabs after one scary drop in a meeting."

• sfm...
• October 18, 2009

"I have been on metformin for 6 years, started at 500 mg per day. Now at 1,000 mg twice per day. Was holding glucose level at 135 with an A1C of 6.4, but my A1C keeps going up, it's more at 7.2 now. Doctor said to now take glipizide 2.5 mg in addition to 2,000 mg of metformin to bring A1C down. I have now been on both medicines for about two weeks. I had a very bad drop in glucose to 73 the first day in a four-hour span after eating. I drank juice to bring up glucose level. The next day it was worse, glucose dropped to 51. I had very bad side effects, I ate some jelly and 4 oz juice. The next day, I decided to not take metformin with breakfast, only 2.5 mg glipizide. Sugar held good for 6 hours but then dropped to 69. I ate supper early - this worked."

• 50-...
• Taken for less than 1 month
• October 11, 2015

"I've had type II diabetes. My doctor recently put me on Watson 461 Glipizide ER. Glucose levels came back under control. After this, the pharmacy switched me to a 'normal' release form. I experienced terrible shoulder aches that woke me up in the middle of the night. I thought these were due to a visit to the gym, but I have been doing exercise for the past three years without pain this bad. It took me a while to realize this is what happened when a previous doctor also put me on glipizide, which resulted in the same excruciating shoulder pain. I've stopped using the medication, and the pain has decreased significantly (I am not woken at night with the excruciating pain anymore, pain is still there in the background). Blurry vision too."

• Emm...
• September 10, 2017

"I have been on Juniva and Metformin for years. It has kept my weight and sugar levels between 91-135. For some reason, my doctor decided to take me off that medication and put me on glipizide. In one month, I had gained 15 pounds, and my blood sugars were in the high 100s to low 200s. After two months, she decided to switch me back on to Juniva. A bit late, I think. My blood sugar is now up into the 300s, and I have packed on another 15 lbs. The glipizide ruined my blood sugars, and an extra bonus, it made me gain weight. DO NOT TAKE GLIPIZIDE FOR A FIRST, SECOND, OR THIRD CHOICE. TRY EVERYTHING ELSE FIRST!!!! There's no out-of-pocket experience, but you pay dearly with your health."