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Sulfonylureas

What are Sulfonylureas?

Sulfonylureas are a group of medicines used in the management of Type 2 diabetes. Sulfonylureas lower blood glucose levels by stimulating insulin release from the Beta cells of the pancreas. Their action is dependent upon the presence of functioning Beta cells, therefore, sulfonylureas do not work in people with type 1 diabetes.

Sulfonylureas stimulate insulin release by blocking ATP sensitive potassium channels in the Beta cells, reducing potassium permeability. This causes depolarization of the cell and increases calcium entry, increasing insulin secretion.

List of Sulfonylureas

View by  Brand | Generic
Drug Name Avg. Rating Reviews
Amaryl (Pro)
Generic name: glimepiride
7.7
 20 reviews
GlipiZIDE XL
Generic name: glipizide
5.4
 10 reviews
Glucotrol (Pro)
Generic name: glipizide
7.6
 9 reviews
Tolinase
Generic name: tolazamide
2.0
 No reviews
Tol-Tab
Generic name: tolbutamide 		No reviews
Micronase
Generic name: glyburide 		No reviews
Glynase PresTab
Generic name: glyburide 		No reviews
Glynase (Pro)
Generic name: glyburide
8.0
 No reviews
Glycron
Generic name: glyburide 		No reviews
Glucotrol XL (Pro)
Generic name: glipizide 		No reviews
Diabinese
Generic name: chlorpropamide
9.0
 No reviews
DiaBeta (Pro)
Generic name: glyburide
7.0
 No reviews
For ratings, users were asked how effective they found the medicine while considering positive/adverse effects and ease of use (1 = not effective, 10 = most effective).

See also

Medical conditions associated with sulfonylureas:

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer