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Sulfonylureas

What are Sulfonylureas?

Sulfonylureas are a group of medicines used in the management of Type 2 diabetes. Sulfonylureas lower blood glucose levels by stimulating insulin release from the Beta cells of the pancreas. Their action is dependent upon the presence of functioning Beta cells, therefore, sulfonylureas do not work in people with type 1 diabetes.

Sulfonylureas stimulate insulin release by blocking ATP sensitive potassium channels in the Beta cells, reducing potassium permeability. This causes depolarization of the cell and increases calcium entry, increasing insulin secretion.

List of Sulfonylureas:

View by  Brand | Generic
Drug Name Reviews Avg. Ratings
Diabinese (Pro)
Generic name: chlorpropamide
0 reviews
9.0
Glynase (Pro)
Generic name: glyburide
0 reviews
8.0
Glucotrol (Pro)
Generic name: glipizide
9 reviews
7.7
Amaryl (Pro)
Generic name: glimepiride
19 reviews
7.6
DiaBeta (Pro)
Generic name: glyburide
0 reviews
7.0
GlipiZIDE XL
Generic name: glipizide
8 reviews
4.9
Tolinase (Pro)
Generic name: tolazamide
0 reviews
2.0
Glucotrol XL (Pro)
Generic name: glipizide
0 reviewsAdd rating
Glycron
Generic name: glyburide
0 reviewsAdd rating
Glynase PresTab
Generic name: glyburide
0 reviewsAdd rating
Micronase (Pro)
Generic name: glyburide
0 reviewsAdd rating
Tol-Tab
Generic name: tolbutamide
0 reviewsAdd rating
For ratings, users were asked how effective they found the medicine while considering positive/adverse effects and ease of use (1 = not effective, 10 = most effective).

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

See Also

Medical conditions associated with sulfonylureas: