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Byetta Dosage

Generic name: exenatide 250ug in 1mL
Dosage form: injection
Drug class: GLP-1 Agonists (Incretin Mimetics)

Medically reviewed by Drugs.com. Last updated on May 28, 2025.

Recommended Dosing

Initiate BYETTA at 5 mcg administered subcutaneously twice daily at any time within the 60-minute period before the morning and evening meals (or before the two main meals of the day, approximately 6 hours or more apart). Do not administer after a meal.
Based on clinical response, the dose of BYETTA can be increased to 10 mcg twice daily which is recommended after 1 month of therapy, in order to reduce the risk of gastrointestinal adverse reactions.
Administer as a subcutaneous injection in the thigh, abdomen, or upper arm.
Rotate injections sites with each dose. Do not use the same site for each injection.
Inspect visually for particulate matter and discoloration. Only use BYETTA if the solution appears clear, colorless, and contains no particles.
When using BYETTA with insulin, administer as separate injections and never mix. It is acceptable to inject BYETTA and insulin in the same body region, but the injections should not be adjacent to each other.
If a dose is missed, resume the treatment regimen as prescribed with the next scheduled dose.

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Frequently asked questions

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Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.