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Januvia (sitagliptin) Drug Interactions

A total of 669 drugs are known to interact with Januvia (sitagliptin).

  • 2 major drug interactions
  • 613 moderate drug interactions
  • 54 minor drug interactions

Show all medications in the database that may interact with Januvia (sitagliptin).

Check for interactions with Januvia (sitagliptin)

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Common medications checked in combination with Januvia (sitagliptin)

  • Aleve (naproxen)
  • amlodipine (Norvasc)
  • aspirin (Aspir 81, Ecotrin, Acetylsalicylic Acid, Aspirin Low Strength, Aspir-Low, Bayer Aspirin, Ecotrin Adult Low Strength, Ascriptin, Fasprin, Arthritis Pain, Low Dose ASA, Aspiritab, Bufferin, Durlaza, Aspirin Lite Coat, Aspirtab, Halfprin, Bayer Children's Aspirin, St. Joseph 81 mg Aspirin Enteric Safety-Coated, Easprin, Aspergum, Buffered Aspirin, Ascriptin Enteric, Acuprin 81, Miniprin, Bayer Aspirin Regimen, St. Joseph 81 mg Chewable Aspirin, Empirin, Ecotrin Maximum Strength, St. Joseph Aspirin, Ecpirin, Bayer Women's Aspirin With Calcium, Ascriptin Maximum Strength, Arthritis Foundation Pain Reliever, Bayer Aspirin with Heart Advantage, Aspi-Cor, Bufferin Low Dose, Medi-Seltzer, Sloprin, ZORprin, Bayer Aspirin Extra Strength Plus, Buffex, Entercote, Extra Strength Bayer, Genacote, Gennin-FC, Genprin, Litecoat Aspirin, Minitabs, Tri-Buffered Aspirin, Entaprin, Bufferin Arthritis Strength, Bufferin Extra Strength, Therapy Bayer, Stanback Analgesic, Norwich Aspirin, Zero-Order Release, YSP Aspirin, Migralex, Heartline, Bayer Advanced Aspirin, Buffasal)
  • Aspirin Low Strength (aspirin)
  • atorvastatin (Lipitor)
  • Bydureon (exenatide)
  • Byetta (exenatide)
  • carvedilol (Coreg, Coreg CR)
  • Crestor (rosuvastatin)
  • furosemide (Lasix, Diaqua-2, Lo-Aqua)
  • gabapentin (Neurontin, Gralise, Gabarone, Fanatrex)
  • glimepiride (Amaryl)
  • glipizide (Glucotrol, GlipiZIDE XL, Glucotrol XL)
  • glyburide (DiaBeta, Micronase, Glynase, Glynase PresTab, Glycron)
  • hydrochlorothiazide (HydroDIURIL, Microzide, Esidrix, Oretic, Diaqua, Aquazide H, Hydro Par, Ezide, Carozide, Loqua)
  • insulin
  • Invokana (canagliflozin)
  • Jardiance (empagliflozin)
  • Lantus (insulin glargine)
  • levothyroxine (Synthroid, Levoxyl, Tirosint, Levothroid, Eltroxin, Unithroid, Levothyrox, Euthyrox, Levo-T, L Thyroxine Roche, Eutroxsig, Novothyrox, Oroxine, Tirosint-Sol, Levotabs, Levotec, Evotrox)
  • Lipitor (atorvastatin)
  • lisinopril (Zestril, Prinivil, Qbrelis)
  • losartan (Cozaar)
  • metformin (Glucophage, Glumetza, Glucophage XR, Riomet, Fortamet)
  • metoprolol (Metoprolol Tartrate, Metoprolol Succinate ER, Lopressor, Toprol-XL, Kapspargo Sprinkle)
  • omeprazole (Prilosec, Prilosec OTC, Zegerid (Original Formulation), Omesec)
  • simvastatin (Zocor, FloLipid)
  • Trulicity (dulaglutide)
  • Victoza (liraglutide)
  • Vitamin D3 (cholecalciferol)

Januvia (sitagliptin) alcohol/food interactions

There is 1 alcohol/food interaction with Januvia (sitagliptin)

Januvia (sitagliptin) disease interactions

There are 2 disease interactions with Januvia (sitagliptin) which include:

Drug Interaction Classification

The classifications below are a general guideline only. It is difficult to determine the relevance of a particular drug interaction to any individual given the large number of variables.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No information available.

Do not stop taking any medications without consulting your healthcare provider.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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