Januvia Alternatives Compared
Januvia (sitagliptin) | Semaglutide | Tirzepatide |
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Januvia (sitagliptin) | Semaglutide | Tirzepatide |
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Prescription only
Januvia is a DPP-4 inhibitor that is used in addition to other medications for the treatment of type 2 diabetes. Rarely, it may cause joint pain, skin reactions, pancreatitis, or an allergic... View more |
Prescription only
Semaglutide lowers blood sugar levels by mimicking the effects of GLP-1, a naturally occurring hormone that stimulates insulin secretion and lowers glucagon secretion from the liver. It is taken... View more |
Prescription only
Prescribed for Weight Loss (Obesity/Overweight), Diabetes - Type 2. Tirzepatide may also be used for purposes not listed in this medication guide. |
Related suggestions |
More about Januvia (sitagliptin) | More about Semaglutide | More about Tirzepatide | |
Ratings & Reviews | |||
Januvia has an average rating of 4.7 out of 10 from a total of 138 ratings on Drugs.com. 31% of reviewers reported a positive effect, while 50% reported a negative effect. |
Semaglutide has an average rating of 6.9 out of 10 from a total of 2341 ratings on Drugs.com. 56% of reviewers reported a positive effect, while 22% reported a negative effect. |
Tirzepatide has an average rating of 8.7 out of 10 from a total of 1431 ratings on Drugs.com. 81% of reviewers reported a positive effect, while 5% reported a negative effect. |
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Drug Class | |||
Side Effects | |||
Generic Availability | |||
N/A |
N/A |
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Pricing and Coupons * Prices are without insurance | |||
We could not find an exact match for this medicine. Try searching the Price Guide directly. |
We could not find an exact match for this medicine. Try searching the Price Guide directly. |
We could not find an exact match for this medicine. Try searching the Price Guide directly. |
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Dosage Forms Available | |||
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N/A |
N/A |
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Brand Names | |||
Other sitagliptin brands include: Zituvio | Ozempic, Rybelsus, Wegovy | Mounjaro, Zepbound | |
Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. | |||
12.4 hours |
168 hours |
120 hours |
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CSA Schedule ** View glossary of terms | |||
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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Pregnancy Category | |||
Category B
No proven risk in humans
See the full pregnancy warnings document. |
Summary unavailable. See the full pregnancy warnings document. |
Summary unavailable. See the full pregnancy warnings document. |
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Drug Interactions | |||
A total of 289 drugs are known to interact with Januvia:
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A total of 266 drugs are known to interact with Semaglutide:
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A total of 411 drugs are known to interact with Tirzepatide:
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Alcohol/Food/Lifestyle Interactions | |||
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Disease Interactions | |||
First Approval Date | |||
October 16, 2006 |
December 05, 2017 |
N/A |
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WADA Class View World Anti-Doping Agency classifications. | |||
N/A |
N/A |
N/A |
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More Information | |||
Patient resources | |||
Professional Resources | |||
Related Treatment Guide | |||
** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.