Comparing Januvia vs Metformin
| Januvia | Metformin |
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| Januvia (sitagliptin) | Metformin |
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Prescription only
Januvia is a DDP-4 inhibitor that is used in addition to other medications for the treatment of type 2 diabetes. Rarely, it may cause joint pain, skin reactions, pancreatitis, or an allergic... View more |
Prescription only
Metformin improves how the body responds to insulin and it is effective for the treatment of type 2 diabetes. Taste disturbances, diarrhea, and other stomach-related side effects are common side... View more |
Related suggestions Diabetes, Type 2
Popular comparisons
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| More about Januvia (sitagliptin) | More about Metformin | ||||||||
| Ratings & Reviews | |||||||||
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Januvia has an average rating of 4.7 out of 10 from a total of 137 ratings on Drugs.com. 31% of reviewers reported a positive effect, while 50% reported a negative effect. |
Metformin has an average rating of 6.9 out of 10 from a total of 648 ratings on Drugs.com. 56% of reviewers reported a positive effect, while 19% reported a negative effect. |
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| Drug Class | |||||||||
| Side Effects | |||||||||
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See also: Januvia side effects in more detail. |
See also: metformin side effects in more detail. |
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| Generic Availability | |||||||||
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Lower cost generic |
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| Pricing and Coupons * Prices are without insurance | |||||||||
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We could not find an exact match for this medicine. Try searching the Price Guide directly. |
View all metformin prices |
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| Dosage Forms Available | |||||||||
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| Brand Names | |||||||||
| Other sitagliptin brands include: Zituvio | Glumetza | ||||||||
| Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. | |||||||||
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12.4 hours |
4.5 hours |
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| CSA Schedule ** View glossary of terms | |||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||
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Category B
No proven risk in humans
See the full pregnancy warnings document. |
Category B
No proven risk in humans
See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||
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A total of 287 drugs are known to interact with Januvia:
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A total of 367 drugs are known to interact with metformin:
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| Alcohol/Food/Lifestyle Interactions | |||||||||
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| Disease Interactions | |||||||||
| First Approval Date | |||||||||
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October 16, 2006 |
March 03, 1995 |
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| WADA Class View World Anti-Doping Agency classifications. | |||||||||
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N/A |
N/A |
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| More Information | |||||||||
| Patient resources | |||||||||
| Professional Resources | |||||||||
| Related Treatment Guide | |||||||||
** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.