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Januvia and Nausea: What Users Say

Nausea: mentioned by 11 users (7.9%)

Based on user experiences from 139 Januvia reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

diarrhea 11.5%
joint pain 8.6%
nausea 7.9%
upset stomach 6.5%
shortness of breath 5.8%
swelling 5.8%
vomiting 5.8%
constipation 4.3%
insomnia 4.3%
stomach pain 4.3%

Reviews for Januvia

Commonly mentioned side effects
  • Anonymous
  • February 6, 2017

For Type 2 Diabetes "I have been on Januvia for about a year and a half. My A1C went down from 9.0 to 8.0. However, I have developed nausea, dizziness, vomiting which I never know when it will hit. Had colonoscopy and they found nothing. In the last six months, developed numbness in my right arm and hand, reflux which keeps me up at night, constant urination about every 45 minutes, and fatigue (this has added three more pills to my daily intake for those symptoms). Told my doctor, and he said to keep taking Januvia and that I was not getting any younger. However, I read here that others have similar side effects once on Januvia."

7 / 10
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  • blu...
  • October 3, 2011

For Type 2 Diabetes "I have been taking Januvia for about a year and have experienced these side effects: difficulty swallowing, pain in the stomach that radiates to my back, hard time eating because of nausea. I finally had to quit taking it. I was also constipated all the time. Now that I am off Januvia, everything is back to normal."

7 / 10
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110 Report
  • Anonymous
  • November 6, 2009

For Type 2 Diabetes "Since starting taking Januvia, I have been throwing up almost every morning. The stomach acid is so strong and now my throat is raw. My stomach constantly churns and very nauseous. Since taking this medicine, I have heartburn and indigestion. My sleeping habits have changed because of the constant stomach churning, and it has been keeping me up. I got tired of being sick every day. This is no way to live and try to enjoy life. I have quit taking Januvia, and now I feel 'normal'. My regular sleeping habits return, and stomach feels fine."

1 / 10
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119 Report

Frequently asked questions

  • ddw...
  • May 13, 2015

For Type 2 Diabetes "The doctor put me on Metformin, which my liver didn't fare well with, and then tried the Januvia 100 mg. After 2.5 weeks, I told him I was experiencing facial, hand, and eyelid swelling and that I felt this wasn't a good fit for me. So, he prescribed Januvia 50 mg, which after three days, caused nausea, upper abdominal pain, orange urine, and skyrocketing blood glucose from low 120's to well over 200's after eating. I immediately quit taking it."

2 / 10
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69 Report
  • esa...
  • Taken for 1 to 6 months
  • December 13, 2018

For Type 2 Diabetes "My type 2 diabetes spiked after getting a high dose of steroids. Januvia was the answer. I took it with zero side effects for several months. Then I noticed an extreme weight loss, currently 82 pounds lost and unfortunately counting. I stopped taking it, and I still had zero appetite. Six months later, and I'm drinking Boost to try and not lose weight and get my appetite back. Any food I liked is no longer good to my taste buds. I can't stomach the taste of most food. After eating, I become nauseous. But my blood sugar is running great."

8 / 10
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43 Report

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  • XYD...
  • July 28, 2016

For Type 2 Diabetes "The side effects of 50 mg Januvia with Metformin ER were horrendous. Painful finger joints. Swelling fingers. Stuffy ears. Unbelievable dizziness, which caused nausea and dry heaves. The diarrhea has been so awful that I can't leave home. I stopped the Januvia 4 days ago. The dizziness stopped first. Then my hands settled down. The diarrhea has not stopped. My doctor believes that I have parasites because Januvia, in conjunction with Metformin ER, doesn't cause diarrhea like this. Getting tested tomorrow, and I have to go back on Januvia. Not looking forward to this at all. What a mess."

1 / 10
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  • Ins...
  • Taken for 6 months to 1 year
  • November 17, 2019

For Type 2 Diabetes "I was diagnosed with diabetes a few years ago and was given Metformin. Immediately, I had severe stomach pains, nausea, and vomiting. I was switched to Amaryl (dropped my blood sugar constantly), then to Oseni (which worked miracles with the right diet). Then there was a shortage, so I was prescribed Januvia! Januvia doesn't drop my blood sugar if I haven't eaten in a while, and I don't have to be as strict with my dieting (no pasta with Amaryl and Oseni vs. pasta with Januvia). With Januvia, my A1C was at a 6.5, and I didn't have any nasty side effects. Januvia is the only medicine I'm on right now for my diabetes, and I'm actually glad my doctor fought to get me the medicine."

10 / 10
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37 Report

More FAQ

  • Cha...
  • Taken for less than 1 month
  • April 16, 2016

For Type 2 Diabetes "This drug came after a bad reaction to Metformin. It is definitely not any better. From day one, I have had diarrhea. And the heaviness in my arms is still present. Now, the leg spasms are showing up, but it is the abdominal pain and the excruciating back pain that take this drug out of the running. I am coming off of it. I can't afford for this drug to kill me. Nausea has been a problem within 3 days of beginning it. Be wary...be alert."

1 / 10
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  • Hol...
  • Taken for less than 1 month
  • March 29, 2022

For Type 2 Diabetes "I'm 75, weigh 138, 5'10', A1C 6.2 - 6.7 with 2 mg Glimepiride + 2000 mg Metformin. Dr. switched me to Januvia 100 mg + 2000 mg Metformin. Blood sugar went out of control from day 1. Over 200 daily average (I test 7 times/day). Morning fasting went from 115 to 226. Nine hours of vomiting and diarrhea on the second day. Nauseous every day for two weeks. Lost 5 lbs in two weeks--I need to gain weight. Stopped after day 14. Very bad drug for me. Dr. now wants me to try another miracle drug: Farxiga. Don't think so as I will need a loan just to buy it."

1 / 10
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  • Anonymous
  • Taken for 6 months to 1 year
  • May 27, 2023

For Type 2 Diabetes "When used with Metformin, I had stomach pain, diarrhea, vomiting, nausea. Without Metformin, I now have a constant backache, leg swelling, increased appetite. I was losing weight before, now I am gaining it back while sticking to my diet. My dosage is 100 mg, once daily, and my blood sugar is still not under control."

3 / 10
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  • dia...
  • Taken for less than 1 month
  • May 23, 2023

For Type 2 Diabetes "Just started taking Januvia, and I am feeling nauseous and having dry heaves."

5 / 10
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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.