Dipeptidyl peptidase 4 inhibitors
Other names: DPP4 inhibitors, gliptans
What are Dipeptidyl peptidase 4 inhibitors?
Dipeptidyl peptidase 4 (DPP-4) inhibitors are a class of medicine that lower high blood glucose levels and may be used in the treatment of type 2 diabetes.
DPP-4 inhibitors slow the inactivation and degradation of GLP-1, a hormone involved in glucose removal from the gut. DPP-4 inhibitors improve blood glucose control and reduce both fasting and postprandial (after food) blood glucose levels, without causing weight gain. They do not usually cause hypoglycemia (low blood sugar levels) unless they are combined with other therapies that cause hypoglycemia.
List of Dipeptidyl peptidase 4 inhibitors
| Drug Name | Avg. Rating | Reviews |
|---|---|---|
| sitagliptin systemic (Pro) Brand names: Januvia, Zituvio, Brynovin |
154 reviews | |
| linagliptin systemic (Pro) Brand name: Tradjenta |
81 reviews | |
| saxagliptin systemic (Pro) Brand name: Onglyza |
17 reviews | |
| alogliptin systemic (Pro) Brand name: Nesina |
9 reviews | |
| For ratings, users were asked how effective they found the medicine while considering positive/adverse effects and ease of use (1 = not effective, 10 = most effective). | ||
See also
Medical conditions treated or associated with dipeptidyl peptidase 4 inhibitors:
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.