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Dipeptidyl peptidase 4 inhibitors

Other names: DPP4 inhibitors, gliptans

What are Dipeptidyl peptidase 4 inhibitors?

Dipeptidyl peptidase 4 (DPP-4) inhibitors are a class of medicine that lower high blood glucose levels and may be used in the treatment of type 2 diabetes.

DPP-4 inhibitors slow the inactivation and degradation of GLP-1, a hormone involved in glucose removal from the gut. DPP-4 inhibitors improve blood glucose control and reduce both fasting and postprandial (after food) blood glucose levels, without causing weight gain. They do not usually cause hypoglycemia (low blood sugar levels) unless they are combined with other therapies that cause hypoglycemia.

List of Dipeptidyl peptidase 4 inhibitors:

View by  Brand | Generic
Drug Name Reviews Avg. Ratings
Onglyza (Pro)
Generic name: saxagliptin
15 reviews
5.9
Januvia (Pro)
Generic name: sitagliptin
111 reviews
5.4
Nesina (Pro)
Generic name: alogliptin
4 reviews
3.0
Tradjenta (Pro)
Generic name: linagliptin
55 reviews
3.0
For ratings, users were asked how effective they found the medicine while considering positive/adverse effects and ease of use (1 = not effective, 10 = most effective).

See Also

Medical conditions associated with dipeptidyl peptidase 4 inhibitors:

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.