Generic Name: alogliptin (AL oh GLIP tin)
Brand Names: Nesina
Medically reviewed on September 5, 2017.
What is Nesina?
Nesina (alogliptin) is an oral diabetes medicine that helps control blood sugar levels. It works by regulating the levels of insulin your body produces after eating.
Nesina is used together with diet and exercise to improve blood sugar control in adults with type 2 diabetes mellitus. This medicine is not for treating type 1 diabetes.
Nesina is sometimes used in combination with other diabetes medications.
Nesina can cause serious side effects on your heart or pancreas, especially if you have ever had similar problems, or if you have kidney or liver disease.
Call your doctor right away if you have: signs of pancreatitis - severe pain in your upper stomach spreading to your back; or signs of heart failure - shortness of breath while lying down, weight gain, swelling in your legs or feet.
Nesina is not for treating type 1 diabetes.
Before taking this medicine
You should not use Nesina if you are allergic to alogliptin, or if you have diabetic ketoacidosis (call your doctor for treatment).
To make sure Nesina is safe for you, tell your doctor if you have ever had:
kidney disease (or if you are on dialysis);
Follow your doctor's instructions about using Nesina if you are pregnant or breast-feeding a baby. Blood sugar control is very important during pregnancy, and your dose needs may be different during each trimester of pregnancy. Your dose needs may also be different while you are breast-feeding.
It is not known whether alogliptin passes into breast milk or if it could harm a nursing baby. Tell your doctor if you are breast-feeding a baby.
Nesina is not approved for use by anyone younger than 18 years old.
How should I take Nesina?
Take Nesina exactly as prescribed by your doctor. Follow all directions on your prescription label. Your doctor may occasionally change your dose. Do not use this medicine in larger or smaller amounts or for longer than recommended.
You may take Nesina with or without food. Follow your doctor's instructions.
Your blood sugar will need to be checked often, and you may need other blood tests at your doctor's office.
Low blood sugar (hypoglycemia) can happen to everyone who has diabetes. Symptoms include headache, hunger, sweating, irritability, dizziness, nausea, fast heart rate, and feeling anxious or shaky. To quickly treat low blood sugar, always keep a fast-acting source of sugar with you such as fruit juice, hard candy, crackers, raisins, or non-diet soda.
Your doctor can prescribe a glucagon emergency injection kit to use in case you have severe hypoglycemia and cannot eat or drink. Be sure your family and close friends know how to give you this injection in an emergency.
Blood sugar levels can be affected by stress, illness, surgery, exercise, alcohol use, or skipping meals. Ask your doctor before changing your dose or medication schedule.
Nesina is only part of a treatment program that may also include diet, exercise, weight control, blood sugar testing, and special medical care. Follow your doctor's instructions very closely.
Store at room temperature away from moisture, heat, and light.
Nesina dosing information
Usual Adult Dose for Diabetes Type 2:
Usual dose: 25 mg orally once a day
Comments: When used in combination with insulin or insulin secretagogues such as sulfonylureas, a lower dose of insulin or the insulin secretagogue may be required to minimize the risk of hypoglycemia.
Use: As an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus; may be used as monotherapy or in combination therapy .
See also: Dosage Information (in more detail)
What happens if I miss a dose?
Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.
What happens if I overdose?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. You may have signs of low blood sugar, such as extreme weakness, blurred vision, sweating, trouble speaking, tremors, stomach pain, confusion, and seizure (convulsions).
What should I avoid while taking Nesina?
Avoid drinking alcohol.
See also: Nesina and alcohol (in more detail)
Nesina side effects
Get emergency medical help if you have signs of an allergic reaction to Nesina: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Stop taking Nesina and call your doctor right away if you have symptoms of pancreatitis: severe pain in your upper stomach spreading to your back, nausea and vomiting, loss of appetite, or fast heartbeats.
Call your doctor at once if you have:
severe or ongoing pain in your joints;
heart problems - shortness of breath (even while lying down), rapid weight gain, swelling (especially in your feet, legs, or midsection);
liver problems - nausea, upper stomach pain, tired feeling, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes);
a severe autoimmune reaction - itching, blisters, breakdown of the outer layer of skin; or
severe skin reaction - fever, sore throat, swelling in your face or tongue, burning in your eyes, skin pain followed by a red or purple skin rash that spreads (especially in the face or upper body) and causes blistering and peeling.
Common Nesina side effects may include:
cold symptoms such as stuffy nose, sinus pain, sore throat.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
See also: Side effects (in more detail)
What other drugs will affect Nesina?
Other drugs may increase or decrease the effects of Nesina on lowering your blood sugar. Tell your doctor about all medications you use. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed in this medication guide.
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use Nesina only for the indication prescribed.
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Copyright 1996-2018 Cerner Multum, Inc. Version: 1.04.
More about Nesina (alogliptin)
- Nesina Side Effects
- During Pregnancy
- Dosage Information
- Drug Images
- Drug Interactions
- Support Group
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- Drug class: dipeptidyl peptidase 4 inhibitors