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Medications for Vaginal Yeast Infection

Other names: Candidiasis, Vaginal; Monilial vaginitis; Thrush; Thrush, Vaginal; Vaginal Candidiasis; Vaginal Thrush; Yeast Infection, vaginal

What is Vaginal Candidiasis?

Vaginal candidiasis is a type of yeast infection in the vagina that is caused by the Candida fungus.

Vaginal yeast infections are common in women, but yeast infections may also affect the mouth, gut, penis, anus, and other parts of the body. Vaginal yeast infections are also known as candidiasis or vaginal thrush.

What Causes Vaginal Candidiasis?

The yeast, Candida Albicans, is the most common cause of vaginal candidiasis. Yeasts are a type of fungus.

Vaginal yeast infections are caused by an overgrowth of yeast within the vagina, and are very common, affecting around 75% of women at least once in their lifetime. A healthy vagina contains bacteria and some yeast cells, but a disruption in the balance of yeast and bacteria causes an overgrowth of yeast cells and symptoms of vaginal thrush.

Factors that may cause a disruption in the balance of bacteria and yeast include:

  • Pregnancy
  • Antibiotic use
  • A weakened immune system
  • Uncontrolled diabetes
  • High-dose estrogen birth control
  • Using vaginal douches or vaginal sprays
  • Wearing tight underwear and synthetic clothes that don’t breathe.

Although vaginal yeast infections are not considered a sexually transmitted infection, sexual intercourse can trigger or spread them. Women who aren’t sexually active can also get them. Some women are prone to yeast infections and get them relatively regularly.
 

What are the Symptoms of Vaginal Candidiasis?

Symptoms of a vaginal candidiasis range may include:

  • Intense itching or irritation around the genital area
  • A burning sensation, especially during intercourse or while urinating
  • A thick, white, odor-free, discharge (may resemble cottage cheese).

How do you Treat Vaginal Candidiasis?

Treatment of vaginal candidiasis usually involves topical or oral antifungals, such as butoconazole, clotrimazole or fluconazole. Symptoms usually resolve quickly, although in more severe cases treatment may be needed for up to two weeks.

How can you Prevent Vaginal Candidiasis?

Eating natural, unsweetened yogurt that contains Lactobacillus acidophilus may help prevent yeast infections occurring.

The risk of yeast infections may also be lessened by staying hydrated and urinating when the need arises, not holding it in.

Women should wipe from front to back after a bowel movement, urinate before and after sex, and avoiding using douches, vaginal sprays, and scented feminine hygiene products.

They should also avoid wearing restrictive, synthetic clothing, or change out of such clothing as soon as possible after exercising or swimming.

 

Drugs Used to Treat Vaginal Yeast Infection

The following list of medications are in some way related to, or used in the treatment of this condition.

Drug name Rx / OTC Pregnancy CSA Alcohol Reviews Rating Popularity
fluconazole C N 367 reviews
6.5

Generic name: fluconazole systemic

Brand name:  Diflucan

Drug class: azole antifungals

For consumers: dosage, interactions,

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Diflucan C N 109 reviews
6.0

Generic name: fluconazole systemic

Drug class: azole antifungals

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

clotrimazole B N 14 reviews
9.1

Generic name: clotrimazole topical

Brand names:  Gyne-Lotrimin, Clotrimazole-3, Gyne-Lotrimin 3 Day

Drug class: vaginal anti-infectives, topical antifungals

For consumers: dosage,

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Gyne-Lotrimin B N 2 reviews
10

Generic name: clotrimazole topical

Drug class: vaginal anti-infectives

For consumers: dosage, side effects

nystatin C N 9 reviews
4.5

Generic name: nystatin topical

Brand names:  Nystop, Nyamyc

Drug class: topical antifungals

For consumers: dosage,

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

miconazole N N 3418 reviews
2.8

Generic name: miconazole topical

Brand names:  Monistat 1 Combination Pack, Monistat 3, Monistat 7, M-Zole 3, Micon 7, Vagistat-3 …show all

Drug class: vaginal anti-infectives, topical antifungals

For consumers: dosage, interactions,

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Clotrimazole-3 B N 1 review
0.0

Generic name: clotrimazole topical

Drug class: vaginal anti-infectives

For consumers: dosage, side effects

terconazole C N 124 reviews
5.9

Generic name: terconazole topical

Brand name:  Terazol

Drug class: vaginal anti-infectives

For consumers: dosage,

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Sporanox C N 5 reviews
10

Generic name: itraconazole systemic

Drug class: azole antifungals

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

ketoconazole Off Label C N X 5 reviews
6.0

Generic name: ketoconazole systemic

Drug class: azole antifungals

For consumers: dosage, interactions,

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Off Label: Yes

Nystop C N 1 review
0.0

Generic name: nystatin topical

Drug class: topical antifungals

For consumers: dosage, side effects

For professionals: AHFS DI Monograph, Prescribing Information

Terazol C N 3 reviews
7.7

Generic name: terconazole topical

Drug class: vaginal anti-infectives

For consumers: dosage, side effects

For professionals: AHFS DI Monograph, Prescribing Information

Gyne-Lotrimin 3 Day B N Add review
0.0

Generic name: clotrimazole topical

Drug class: vaginal anti-infectives

For consumers: dosage, side effects

itraconazole C N 7 reviews
9.2

Generic name: itraconazole systemic

Brand names:  Sporanox, Onmel

Drug class: azole antifungals

For consumers: dosage, interactions,

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Nyamyc C N Add review
0.0

Generic name: nystatin topical

Drug class: topical antifungals

For consumers: dosage, side effects

For professionals: Prescribing Information

boric acid N N 9 reviews
7.4

Generic name: boric acid topical

Brand name:  Hylafem

Drug class: topical anti-infectives

For consumers: dosage,

Gynazole-1 C N 2 reviews
8.5

Generic name: butoconazole topical

Drug class: vaginal anti-infectives

For consumers: dosage, side effects

For professionals: Prescribing Information

Monistat 1 Combination Pack N N 211 reviews
3.3

Generic name: miconazole topical

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

Monistat 3 N N 540 reviews
3.3

Generic name: miconazole topical

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

Monistat 7 N N 617 reviews
3.4

Generic name: miconazole topical

Drug class: vaginal anti-infectives

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

tioconazole C N 1593 reviews
4.1

Generic name: tioconazole topical

Brand names:  Vagistat-1, Tioconazole 1 Day

Drug class: vaginal anti-infectives

For consumers: dosage,

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

butoconazole C N 2 reviews
8.5

Generic name: butoconazole topical

Brand name:  Gynazole-1

Drug class: vaginal anti-infectives

For consumers: dosage,

For professionals: A-Z Drug Facts, AHFS DI Monograph

M-Zole 3 N N 3 reviews
1.0

Generic name: miconazole topical

Drug class: vaginal anti-infectives, topical antifungals

For consumers: dosage, interactions, side effects

Micon 7 N N 2 reviews
7.0

Generic name: miconazole topical

Drug class: vaginal anti-infectives, topical antifungals

For consumers: dosage, interactions, side effects

Onmel C N Add review
0.0

Generic name: itraconazole systemic

Drug class: azole antifungals

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

Alternative treatments for Vaginal Yeast Infection

The following products are considered to be alternative treatments or natural remedies for Vaginal Yeast Infection. Their efficacy may not have been scientifically tested to the same degree as the drugs listed in the table above. However there may be historical, cultural or anecdotal evidence linking their use to the treatment of Vaginal Yeast Infection.

Learn more about Vaginal Yeast Infection

Symptoms and treatments

Legend

Rx Prescription Only
OTC Over the Counter
Rx/OTC Prescription or Over the Counter
Off Label This medication may not be approved by the FDA for the treatment of this condition.
Pregnancy Category
A Adequate and well-controlled studies have failed to demonstrate a risk to the fetus in the first trimester of pregnancy (and there is no evidence of risk in later trimesters).
B Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women.
C Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
D There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
X Studies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use in pregnant women clearly outweigh potential benefits.
N FDA has not classified the drug.
Controlled Substances Act (CSA) Schedule
N Is not subject to the Controlled Substances Act.
1 Has a high potential for abuse. Has no currently accepted medical use in treatment in the United States. There is a lack of accepted safety for use under medical supervision.
2 Has a high potential for abuse. Has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse may lead to severe psychological or physical dependence.
3 Has a potential for abuse less than those in schedules 1 and 2. Has a currently accepted medical use in treatment in the United States. Abuse may lead to moderate or low physical dependence or high psychological dependence.
4 Has a low potential for abuse relative to those in schedule 3. It has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 3.
5 Has a low potential for abuse relative to those in schedule 4. Has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 4.
Alcohol
X Interacts with Alcohol.

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Further information

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