Tioconazole Topical Side Effects

Medically reviewed by Drugs.com. Last updated on Dec 13, 2023.

Applies to tioconazole topical: intravaginal ointment.

Side effects include:

Vulvovaginal burning, irritation, vaginitis, pruritus, headache.

For healthcare professionals

Applies to tioconazole topical: vaginal ointment w/applicator.

Other adverse events

Topical solution:

• Common (1% to 10%): Peripheral edema
• Frequency not reported: Pain^[Ref]

Dermatologic

Topical solution:

• Uncommon (0.1% to 1%): Rash, dermatitis
• Frequency not reported: Bullous eruption, contact dermatitis, dry skin, nail disorder (including nail discoloration, periungual inflammation, nail pain), pruritus, skin irritation, skin exfoliation, urticaria^[Ref]

Local

Topical solution:

• Frequency not reported: Local irritation (including local allergic reactions)

Vaginal ointment:

• Frequency not reported: Burning, itching, pain, irritation, dryness^[Ref]

Topical solution: Local irritation (including local allergic reactions) usually occurred during the first week of therapy and was transient and mild.^[Ref]

Genitourinary

Vaginal ointment:

• Frequency not reported: Increased vaginal burning, increased vaginal itching, increased vaginal irritation, vaginal swelling/redness, difficulty/burning on urination^[Ref]

Gastrointestinal

Vaginal ointment:

• Frequency not reported: Abdominal pain/cramping^[Ref]

Hypersensitivity

Topical solution:

• Frequency not reported: Allergic reaction

Other formulations than the dermatological preparation:

• Frequency not reported: Anaphylactoid reactions^[Ref]

Nervous system

Topical solution:

• Frequency not reported: Paresthesia

Vaginal ointment:

• Frequency not reported: Headache^[Ref]

Ocular

Topical solution:

• Frequency not reported: Periorbital edema^[Ref]

Respiratory

Vaginal ointment:

• Frequency not reported: Upper respiratory infection^[Ref]

Further information

Tioconazole topical side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.

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