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Itraconazole Dosage

Medically reviewed by Drugs.com. Last updated on Aug 4, 2023.

Applies to the following strengths: 100 mg; 200 mg; 10 mg/mL; 250 mg; 65 mg

Usual Adult Dose for Blastomycosis

100-mg Capsules:


65-mg Capsules:

Duration of Therapy: At least 3 months and until clinical parameters and laboratory tests indicate the active fungal infection has subsided

Comments:

Use: For the treatment of blastomycosis (pulmonary and extrapulmonary) in immunocompromised and non-immunocompromised patients

Infectious Diseases Society of America (IDSA) Recommendations:

Comments:

Usual Adult Dose for Histoplasmosis

100-mg Capsules:


65-mg Capsules:

Duration of Therapy: At least 3 months and until clinical parameters and laboratory tests indicate the active fungal infection has subsided

Comments:

Use: For the treatment of histoplasmosis (including chronic cavitary pulmonary disease and disseminated, nonmeningeal histoplasmosis) in immunocompromised and non-immunocompromised patients

IDSA Recommendations:

US CDC, National Institutes of Health (NIH), and HIV Medicine Association of the IDSA (HIVMA/IDSA) Recommendations for HIV-Infected Patients:

Comments:

Usual Adult Dose for Aspergillosis - Aspergilloma

100-mg Capsules:


65-mg Capsules:

Duration of Therapy: At least 3 months and until clinical parameters and laboratory tests indicate the active fungal infection has subsided

Comments:

Use: For the treatment of aspergillosis (pulmonary and extrapulmonary) in immunocompromised and non-immunocompromised patients who are intolerant of, or refractory to, amphotericin B therapy

IDSA Recommendations: 200 mg orally every 12 hours

Comments:

Usual Adult Dose for Aspergillosis - Invasive

100-mg Capsules:


65-mg Capsules:

Duration of Therapy: At least 3 months and until clinical parameters and laboratory tests indicate the active fungal infection has subsided

Comments:

Use: For the treatment of aspergillosis (pulmonary and extrapulmonary) in immunocompromised and non-immunocompromised patients who are intolerant of, or refractory to, amphotericin B therapy

IDSA Recommendations: 200 mg orally every 12 hours

Comments:

Usual Adult Dose for Oral Thrush

Oral Solution:


Comments:

Use: For the treatment of oropharyngeal candidiasis

IDSA Recommendations:

US CDC, NIH, and HIVMA/IDSA Recommendations for HIV-Infected Patients:

Comments:

Usual Adult Dose for Esophageal Candidiasis

Oral Solution: 100 mg orally once a day for at least 3 weeks and for 2 weeks after symptoms resolve

Comments:


Use: For the treatment of esophageal candidiasis

IDSA Recommendations:

US CDC, NIH, and HIVMA/IDSA Recommendations for HIV-Infected Patients:

Comments:

Usual Adult Dose for Onychomycosis - Toenail

100-mg Capsules: 200 mg orally once a day for 12 consecutive weeks

Comments:


Use: For the treatment of onychomycosis of the toenail (with or without fingernail involvement) due to dermatophytes (tinea unguium) in non-immunocompromised patients

Usual Adult Dose for Onychomycosis - Fingernail

100-mg Capsules:


Comments:

Use: For the treatment of onychomycosis of the fingernail due to dermatophytes (tinea unguium) in non-immunocompromised patients

Usual Adult Dose for Coccidioidomycosis

IDSA Recommendations: 200 mg orally twice a day


Duration of Therapy:

US CDC, NIH, and HIVMA/IDSA Recommendations for HIV-Infected Patients:

Comments:

Usual Adult Dose for Sporotrichosis

IDSA Recommendations:


Comments:

Usual Adult Dose for Cryptococcosis

IDSA Recommendations:


Comments:

Usual Adult Dose for Cryptococcal Meningitis - Immunosuppressed Host

US CDC, NIH, and HIVMA/IDSA Recommendations for HIV-Infected Patients:


Comments:

Usual Adult Dose for Vaginal Candidiasis

US CDC, NIH, and HIVMA/IDSA Recommendations for HIV-Infected Patients:


Comments:

Usual Adult Dose for Microsporidiosis

US CDC, NIH, and HIVMA/IDSA Recommendations for HIV-Infected Patients: 400 mg orally per day

Comments:

Usual Adult Dose for Paracoccidioidomycosis

Some Experts Recommend: 200 mg orally once a day for 9 to 18 months

Comments:

Usual Pediatric Dose for Blastomycosis

IDSA Recommendations for Children:


Comments:

Usual Pediatric Dose for Histoplasmosis

IDSA Recommendations for Children:


US CDC, NIH, HIVMA/IDSA, Pediatric Infectious Diseases Society (PIDS), and American Academy of Pediatrics (AAP) Recommendations for HIV-Exposed and HIV-Infected Children:

US CDC, NIH, and HIVMA/IDSA Recommendations for HIV-Infected Adolescents:

Comments:

Usual Pediatric Dose for Oral Thrush

US CDC, NIH, HIVMA/IDSA, PIDS, and AAP Recommendations for HIV-Exposed and HIV-Infected Children:
Oral solution:


US CDC, NIH, and HIVMA/IDSA Recommendations for HIV-Infected Adolescents:
Oral solution: 200 mg orally per day for 7 to 14 days

Comments:

Usual Pediatric Dose for Esophageal Candidiasis

US CDC, NIH, HIVMA/IDSA, PIDS, and AAP Recommendations for HIV-Exposed and HIV-Infected Children:


US CDC, NIH, and HIVMA/IDSA Recommendations for HIV-Infected Adolescents:

Comments:

Usual Pediatric Dose for Coccidioidomycosis

US CDC, NIH, HIVMA/IDSA, PIDS, and AAP Recommendations for HIV-Exposed and HIV-Infected Children:


US CDC, NIH, and HIVMA/IDSA Recommendations for HIV-Infected Adolescents:

Comments:

Usual Pediatric Dose for Cryptococcosis

US CDC, NIH, HIVMA/IDSA, PIDS, and AAP Recommendations for HIV-Exposed and HIV-Infected Children:


Comments:

Usual Pediatric Dose for Cryptococcal Meningitis - Immunosuppressed Host

US CDC, NIH, HIVMA/IDSA, PIDS, and AAP Recommendations for HIV-Exposed and HIV-Infected Children:


US CDC, NIH, and HIVMA/IDSA Recommendations for HIV-Infected Adolescents:

Comments:

Usual Pediatric Dose for Vaginal Candidiasis

US CDC, NIH, and HIVMA/IDSA Recommendations for HIV-Infected Adolescents:


Comments:

Usual Pediatric Dose for Microsporidiosis

US CDC, NIH, and HIVMA/IDSA Recommendations for HIV-Infected Adolescents: 400 mg orally per day

Comments:

Usual Pediatric Dose for Sporotrichosis

IDSA Recommendations for Children:


Comments:

Renal Dose Adjustments

Renal dysfunction: Dose adjustment(s) may be required; however, no specific guidelines have been suggested. Caution recommended.

Comments:

Liver Dose Adjustments

Liver dysfunction: Caution recommended.

Comments:

Dose Adjustments

Some experts recommend adjusting dose based on drug serum levels and/or drug interactions.

Precautions

US BOXED WARNINGS:


CONTRAINDICATIONS:

Safety and efficacy have not been established in patients younger than 18 years.

Consult WARNINGS section for additional precautions.

Dialysis

Data not available

Comments:

Other Comments

Administration advice:

100-mg Capsules:
65-mg Capsules:
Oral Solution:

Storage requirements:

General:

Monitoring:

Patient advice:

Frequently asked questions

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.