Generic name: Itraconazole Tablets [ i-tra-KOE-na-zole ]
Brand name: Onmel
Drug class: Azole antifungals
Medically reviewed by Drugs.com. Last updated on Feb 22, 2023.
- Heart failure (weak heart) has happened with this medicine (itraconazole tablets). If you have or have ever had heart failure, talk with your doctor. Get medical help right away if you have signs of heart failure like shortness of breath, a big weight gain, coughing up white or pink mucus, fast heartbeat, waking up at night more than normal, or swelling in the arms or legs while you take this medicine (itraconazole tablets).
- This medicine interacts with many other drugs. This may affect how well this medicine (itraconazole tablets) works or cause side effects. Sometimes, these effects may be severe or deadly. Do not take this medicine (itraconazole tablets) if you are taking any of these drugs: Avanafil, cisapride, dihydroergotamine, disopyramide, dofetilide, dronedarone, eplerenone, ergonovine, ergotamine, felodipine, irinotecan, isavuconazole, ivabradine, lomitapide, lovastatin, lurasidone, methadone, methylergonovine, oral midazolam, naloxegol, nisoldipine, pimozide, quinidine, ranolazine, simvastatin, ticagrelor, or triazolam. Some patients must not take this medicine (itraconazole tablets) with eliglustat. There are many other drugs that must not be taken with this medicine (itraconazole tablets). Check with your doctor and pharmacist to make sure that it is safe for you to take all of your other drugs (prescription or OTC, natural products, vitamins) with this medicine (itraconazole tablets) or within 2 weeks after you stop taking this medicine (itraconazole tablets).
- If you have kidney or liver problems, do not take this medicine (itraconazole tablets) if you are also taking fesoterodine, solifenacin, or a drug that has colchicine in it.
Uses of Itraconazole Tablets:
- It is used to treat fungal infections.
What do I need to tell my doctor BEFORE I take Itraconazole Tablets?
For all uses of this medicine (itraconazole tablets):
- If you have an allergy to itraconazole or any other part of this medicine (itraconazole tablets).
- If you are allergic to this medicine (itraconazole tablets); any part of this medicine (itraconazole tablets); or any other drugs, foods, or substances. Tell your doctor about the allergy and what signs you had.
Nail fungal infections:
- If you are pregnant or may be pregnant. Do not take this medicine (itraconazole tablets) if you are pregnant.
This medicine may interact with other drugs or health problems.
Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take this medicine (itraconazole tablets) with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.
What are some things I need to know or do while I take Itraconazole Tablets?
For all uses of this medicine (itraconazole tablets):
- Tell all of your health care providers that you take this medicine (itraconazole tablets). This includes your doctors, nurses, pharmacists, and dentists.
- Avoid driving and doing other tasks or actions that call for you to be alert until you see how this medicine (itraconazole tablets) affects you.
- If you have dizziness or change in eyesight, do not drive or do other tasks or actions that could be unsafe.
- Have blood work checked as you have been told by the doctor. Talk with the doctor.
- If you have high blood sugar (diabetes), you will need to watch your blood sugar closely.
- Do not use longer than you have been told. A second infection may happen.
- Talk with your doctor before you drink alcohol.
- Hearing loss has happened with this medicine (itraconazole tablets). Many times this has happened when this medicine (itraconazole tablets) was taken along with quinidine. This will most often go away after this medicine (itraconazole tablets) is stopped but may last for a long time in some people. Talk with your doctor.
- If you are 65 or older, use this medicine (itraconazole tablets) with care. You could have more side effects.
- Use birth control that you can trust to prevent pregnancy while taking this medicine (itraconazole tablets) and for at least 2 months after your last dose.
- If you get pregnant while taking this medicine (itraconazole tablets) or within 2 months after your last dose, call your doctor right away.
- Tell your doctor if you are breast-feeding. You will need to talk about any risks to your baby.
Nail fungal infections:
- It may take a few weeks to months to see the full effect.
How is this medicine (Itraconazole Tablets) best taken?
Use this medicine (itraconazole tablets) as ordered by your doctor. Read all information given to you. Follow all instructions closely.
- Keep taking this medicine (itraconazole tablets) as you have been told by your doctor or other health care provider, even if you feel well.
- Take this medicine (itraconazole tablets) at the same time of day.
- Take this medicine (itraconazole tablets) with a full meal.
- If you have low stomach acid or you take another drug to lower stomach acid, talk with your doctor about how to take this medicine (itraconazole tablets). You may need to take this medicine (itraconazole tablets) with an acidic drink like non-diet cola.
What do I do if I miss a dose?
- Take a missed dose as soon as you think about it.
- If it is close to the time for your next dose, skip the missed dose and go back to your normal time.
- Do not take 2 doses at the same time or extra doses.
What are some side effects that I need to call my doctor about right away?
WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:
- Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
- Signs of electrolyte problems like mood changes, confusion, muscle pain or weakness, a heartbeat that does not feel normal, seizures, not hungry, or very bad upset stomach or throwing up.
- Signs of high blood sugar like confusion, feeling sleepy, more thirst, more hungry, passing urine more often, flushing, fast breathing, or breath that smells like fruit.
- Signs of high or low blood pressure like very bad headache or dizziness, passing out, or change in eyesight.
- A burning, numbness, or tingling feeling that is not normal.
- Trouble passing urine.
- Chest pain or pressure.
- Fever or chills.
- Change in eyesight.
- Feeling confused.
- Ringing in the ears, hearing loss, or any other changes in hearing.
- Lowered interest in sex.
- Not able to get or keep an erection.
- Very bad and sometimes deadly liver problems have rarely happened with this medicine (itraconazole tablets). Sometimes this happened within 7 days of starting this drug. Call your doctor right away if you have signs of liver problems like dark urine, feeling tired, not hungry, upset stomach or stomach pain, light-colored stools, throwing up, or yellow skin or eyes.
What are some other side effects of Itraconazole Tablets?
All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:
- Upset stomach or throwing up.
- Stomach pain or diarrhea.
- Runny nose.
- Feeling tired or weak.
- Not hungry.
- Feeling sleepy.
These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.
You may report side effects to the FDA at 1-800-332-1088. You may also report side effects at https://www.fda.gov/medwatch.
If OVERDOSE is suspected:
If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.
How do I store and/or throw out Itraconazole Tablets?
- Store at room temperature. Do not freeze.
- Protect from light.
- Store in a dry place. Do not store in a bathroom.
- Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.
- Throw away unused or expired drugs. Do not flush down a toilet or pour down a drain unless you are told to do so. Check with your pharmacist if you have questions about the best way to throw out drugs. There may be drug take-back programs in your area.
Consumer Information Use and Disclaimer
- If your symptoms or health problems do not get better or if they become worse, call your doctor.
- Do not share your drugs with others and do not take anyone else's drugs.
- Some drugs may have another patient information leaflet. Check with your pharmacist. If you have any questions about this medicine (itraconazole tablets), please talk with your doctor, nurse, pharmacist, or other health care provider.
- If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.
Frequently asked questions
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- Drug class: azole antifungals
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