Vagistat-1 Side Effects
Generic Name: tioconazole topical
Note: This document contains side effect information about tioconazole topical. Some of the dosage forms listed on this page may not apply to the brand name Vagistat-1.
For the Consumer
Applies to tioconazole topical: topical cream
Along with its needed effects, tioconazole topical (the active ingredient contained in Vagistat-1) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor as soon as possible if any of the following side effects occur while taking tioconazole topical:
- skin rash
- or other signs of skin irritation not present before use of this medicine
For Healthcare Professionals
Applies to tioconazole topical: vaginal ointment w/applicator
Local side effects have been commonly reported. These have involved the genitourinary area (occurring in up to 7% of treated patients), and have included burning, itching, and, less commonly, pain, irritation, and dryness.[Ref]
Hypersensitivity side effects have included contact dermatitis in patients using a topical nail solution (not available in the US). Most patients had been using the product for several weeks when dermatitis developed. Cross-sensitivity to other imidazoles has been reported.[Ref]
1. Clissold SP, Heel RC "Tioconazole. A review of its antimicrobial activity and therapeutic use in superficial mycoses." Drugs 31 (1986): 29-51
2. "Product Information. Vagistat-1 (tioconazole)." Bristol-Myers Squibb, Princeton, NJ.
3. Stein GE, Gurwith D, Mummaw N, Gurwith M "Single-dose tioconazole compared with 3-day clotrimazole treatment in vulvovaginal candidiasis." Antimicrob Agents Chemother 29 (1986): 969-71
4. Onayemi O, Aldridge RD, Shaw S "Allergic contact dermatitis from tioconazole. A report of 2 cases." Contact Dermatitis 26 (1992): 193-4
5. Brunelli D, Vincenzi C, Morelli R, Tosti A "Contact dermatitis from tioconazole." Contact Dermatitis 27 (1992): 120
6. Piletta P, Pasche-Koo F, Saurat JH "Contact dermatitis from tioconazole mimicking "one hand two feet syndrome"." Contact Dermatitis 28 (1993): 308
7. Marren P, Powell S "Contact sensitivity to tioconazole and other imidazoles." Contact Dermatitis 27 (1992): 129-30
8. Gibson G, Buckley A, Murphy GM "Allergic contact dermatitis from tioconazole without cross- sensitivity to other imidazoles." Contact Dermatitis 30 (1994): 308
9. Stubb S, Heikkila H, Reitamo S, Forstrom L "Contact allergy to tioconazole." Contact Dermatitis 26 (1992): 155-8
10. Izu R, Aguirre A, Gonzalez M, Diaz-Perez JL "Contact dermatitis from tioconazole with cross-sensitivity to other imidazoles." Contact Dermatitis 26 (1992): 130-1
11. Quirino AP, Barros MA "Contact dermatitis from tioconazole." Contact Dermatitis 30 (1994): 240-1
12. Jones SK, Kennedy CT "Contact dermatitis from tioconazole." Contact Dermatitis 22 (1990): 122-3
13. Faria A, Goncalo S, Goncalo M, Freitas C, Baptista PP "Allergic contact dermatitis from tioconazole." Contact Dermatitis 35 (1996): 250-2
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Some side effects may not be reported. You may report them to the FDA.
More about Vagistat-1 (tioconazole topical)
- Vagistat-1 Side Effects
- During Pregnancy or Breastfeeding
- Dosage Information
- Support Group
- En Español
- 12 Reviews
- Drug class: vaginal anti-infectives
Other brands: Tioconazole 1 Day