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Gynazole-1 Side Effects

Generic Name: butoconazole topical

Note: This page contains information about the side effects of butoconazole topical. Some of the dosage forms included on this document may not apply to the brand name Gynazole-1.

For the Consumer

Applies to butoconazole topical: intravaginal cream

Side effects include:

Vulvar/vaginal burning, itching, soreness and swelling, pelvic or abdominal pain or cramping.

For Healthcare Professionals

Applies to butoconazole topical: vaginal cream

Genitourinary

Common (1% to 10%): Vulvar/vaginal burning, itching, soreness, swelling; pelvic pain or cramping[Ref]

Local

Frequency not reported: Irritation[Ref]

Gastrointestinal

Common (1% to 10%): Abdominal pain or cramping[Ref]

Nervous system

Frequency not reported: Headache[Ref]

Hematologic

Thrombocytopenia developed 1 week after beginning this drug. It resolved slowly over the next few weeks after drug discontinuation.[Ref]

Frequency not reported: Thrombocytopenia[Ref]

References

1. Brown D Jr, Henzl MR, LePage ME, Tsao LL, Izu AE, Walker KA, Adamson GD, Droegmuller W "Butoconazole vaginal cream in the treatment of vulvovaginal candidiasis. Comparison with miconazole nitrate and placebo." J Reprod Med 31 (1986): 1045-8

2. Ruf H, Vitse M "A comparison of butoconazole nitrate cream with econazole nitrate cream for the treatment of vulvovaginal candidiasis." J Int Med Res 18 (1990): 389-99

3. "Butoconazole or vulvovaginal candidiasis." Med Lett Drugs Ther 28 (1986): 68

4. "Product Information. Femstat (butoconazole)." Syntex Laboratories Inc, Palo Alto, CA.

5. Maloley PA, Nelson E, Montgomery HA, Campbell JR "Severe reversible thrombocytopenia resulting from butoconazole cream." DICP 24 (1990): 143-4

Not all side effects for Gynazole-1 may be reported. You should always consult a doctor or healthcare professional for medical advice. Side effects can be reported to the FDA here.

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