What is Restasis?
Restasis eye drops contain cyclosporine which is an immunosuppressant. Cyclosporine can increase tear production that has been reduced by inflammation in the eye(s).
Restasis eye drops are used to treat chronic dry eye that may be caused by inflammation.
Restasis ophthalmic emulsion may also be used for treating eye disease not listed in this medication guide.
Do not touch the Restasis dropper on to any surface, including the eyes or hands. The dropper is sterile. If it becomes contaminated (dirty), it could cause an infection in the eye(s).
Do not use this medicine while wearing contact lenses. Contact lenses may be reinserted 15 minutes following the administration of Restasis eye drops, unless otherwise directed by your doctor.
Before taking this medicine
You should not use Restasis if you are allergic to cyclosporine.
Restasis is likely safe in pregnancy. Tell your doctor if you are pregnant or plan to become pregnant.
It is not known whether Restasis passes into breast milk or if it could harm a nursing baby, although it is likely safe. Tell your doctor if you are breast-feeding a baby.
This medicine is not approved for use by anyone younger than 16 years old.
How should I use Restasis?
Use Restasis eye drops exactly as directed by your doctor. Follow all directions on your prescription label. Do not use the eye drops in larger or smaller amounts or for longer than recommended.
The usual dose is 1 drop in each eye twice daily. Use Restasis eye drops every 12 hours (approximately).
Read all patient information, medication guides, and instruction sheets provided to you. Ask your doctor or pharmacist if you have any questions.
Wash your hands before using the eye drops.
To apply the eye drops:
Turn the bottle upside down a few times to gently mix the medicine. Restasis eye drops should appear white in color.
Tilt your head back slightly and pull down your lower eyelid to create a small pocket. Hold the dropper above the eye with the tip down. Look up and away from the dropper and squeeze out a drop.
Close your eyes for 2 or 3 minutes with your head tipped down, without blinking or squinting. Gently press your finger to the inside corner of the eye for about 1 minute, to keep the liquid from draining into your tear duct.
Wait at least 15 minutes before using artificial tears, or any other eye drops your doctor has prescribed.
Do not touch the tip of the eye dropper or place it directly on your eye. A contaminated (dirty) dropper can infect your eye, which could lead to serious vision problems.
Do not use the drops if the liquid has changed colors or has particles in it. Call your pharmacist for new medicine.
Each single-use bottle of Restasis is for one use only (in one or both eyes). Throw away the bottle after one use, even if there is still some medicine left in it.
Store at room temperature away from moisture and heat. Do not freeze. Keep the bottle tightly closed when not in use.
1 drop 2 times a day in each eye approximately 12 hours apart
Restasis can be used concomitantly with artificial tears, allowing a 15 minute interval between products.
What happens if I miss a dose?
Apply the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next dose. Do not use extra medicine to make up the missed dose.
What happens if I overdose?
An overdose of Restasis is not expected to be dangerous. Seek emergency medical attention or call the Poison Help line at 1-800-222-1222 if anyone has accidentally swallowed the medication.
What should I avoid while using Restasis?
You should not put Restasis in your eyes while wearing contact lenses. Wait at least 15 minutes after using this medicine before putting in your contact lenses. It may be best not to wear contact lenses if you have dry eyes. Talk with your doctor about your own risk.
Restasis side effects
Get emergency medical help if you have signs of an allergic reaction to Restasis: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Stop using this medicine and call your doctor at once if you have:
eye pain; or
eye swelling, redness, severe discomfort, crusting or drainage (may be signs of infection).
Common Restasis side effects may include:
mild burning or stinging in the eyes;
mild redness or itching;
blurred vision; or
feeling like something is in your eye.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
What other drugs will affect Restasis?
It is not likely that other drugs you take orally or inject will have an effect on cyclosporine used in the eyes. But many drugs can interact with each other. Tell each of your healthcare providers about all medicines you use, including prescription and over-the-counter medicines, vitamins, and herbal products.
Yes, in the U.S. there is a generic option for Restasis eye drops known as cyclosporine ophthalmic eye drops. The generic was first approved in February 2022. It comes as a 0.05% strength in a package that contains 30 or 60 single-dose vials. The generic is just as safe and effective as the brand name. Continue reading
Restasis (cyclosporine 0.05% ophthalmic emulsion), from Allergan, was formerly only available as a brand name prescription product. Cyclosporine 0.05% ophthalmic emulsion, made by Mylan, is now available as a more affordable generic option in the U.S. Continue reading
No, Restasis (cyclosporine ophthalmic) eye drops require a prescription from your doctor, you cannot buy them over the counter (OTC). An optometrist or ophthalmologist are eye doctor specialists that usually prescribe this medicine. This drug is approved to treat dry eye disease. Continue reading
Restasis withdrawal symptoms do not usually occur, but clinical studies have shown your persistent dry eye symptoms may return if you stop treatment. Depending upon your symptoms, you may need 3 to 6 months of Restasis treatment before your dry eyes start to improve. Restasis is typical meant for long-term use, but some patients may be able to stop treatment after 6 months. Continue reading
Both Cequa and Restasis are eye drops that contain cyclosporine. They are used to increase tear production in patients with dry eye disease (medically called keratoconjunctivitis sicca). However, Cequa incorporates a novel nanomicellar technology of cyclosporine A to allow delivery of high concentrations of the medication into the eye. Restasis is not manufactured using nanomicellar technology. Nanomicellar technology can help deliver poorly water-soluble drugs into the eye and protect the drug molecule. Continue reading
One bottle of Restasis MultiDose (cyclosporine ophthalmic emulsion) contains a little over 120 doses/drops. One drop of Restasis MultiDose should be administered into each eye twice daily, amounting to 4 drops total, which means that one bottle should last a little longer than 30 days. For a 90-day supply, patients will be given 3 bottles at a time.
A prescription of non-multidose Restasis (cyclosporine ophthalmic emulsion) comes with 30 or 60 single-use vials. One single-use vial can be used to administer two drops, one in each eye, immediately after opening. Patients are intended to use two vials per day about 12 hours apart. Thirty single-use vials provide a 15-day supply, while 60 vials provide a 30-day supply.
Restasis is the same price whether it is supplied in multidose bottles or single-use vials. Prices will vary depending on the pharmacy and your insurance coverage. Continue reading
Only use Xiidra and Restasis together if your doctor has recommended this treatment. Both drugs are used to treat dry eye disease and inflammation and you would not usually need to combine them. Both Xiidra and Restasis can be linked with similar side effects such as eye burning, stinging and irritation. Continue reading
Restasis (cyclosporine ophthalmic emulsion) should not make your eyelashes fall out. Clinical trials of Restasis have not identified loss of eyelashes or any other changes in eyelash growth to be a potential side effect of using Restasis eye drops.
While there is no evidence that Restasis should have any effect on eyelashes, older studies have suggested that Restasis could potentially be linked to both excessive eyelash growth and eyelash shortening. One 2011 case report in Case Reports in Ophthalmology described a patient who developed elongated eyelashes after using Restasis for 5 months. In contrast with this finding, an older study from 2007 in the International Journal of Immunopathology and Pharmacology found that in a very small group of children with an allergic eye condition (vernal keratoconjunctivitis), those treated with Restasis had shorter eyelashes than those who were not using Restasis. However, the authors suggest that patients with vernal keratoconjunctivitis often have elongated eyelashes as a protective symptom of the condition and that the potential shortening effect of Restasis is a natural result of treating the disease itself. Continue reading
No, Restasis is not a steroid eye drop. Restasis contains cyclosporine 0.05% ophthalmic, an eye drop used to treat chronic dry eye (also called keratoconjunctivitis sicca) that may be caused by inflammation. Continue reading
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Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use Restasis only for the indication prescribed.
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
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