Why is Restasis so expensive?

Medically reviewed by Leigh Ann Anderson, PharmD. Last updated on May 26, 2025.

Official Answer by Drugs.com

Restasis (cyclosporine 0.05% ophthalmic emulsion), from Allergan, was formerly only available as a brand name prescription product. Cyclosporine 0.05% ophthalmic emulsion is now available as a more affordable generic option in the U.S.

Like the brand name product Restasis, cyclosporine ophthalmic emulsion has been approved by the FDA to increase tear production in patients with ocular inflammation associated with keratoconjunctivitis sicca, also known as chronic dry eye disease. It is available in single-use vials, but not as a multi-dose bottle.

Learn More: Is there a generic for Restasis eye drops?

Why are brand name drugs so expensive?

Brand name drugs can be expensive because they are the first products on the market and usually do not have a more affordable generic alternative. Manufacturers may price brand name products at high levels to recoup the expenses involved with the original research, drug development and product manufacturing, plus make a profit. There is no competition. This can push up the price greatly.

Original inventors of the drug will have a patent on the product and no other manufacturers can market the generic until the patent expires, which can take 10 years or longer. Drug pricing in the U.S. is complicated and the government does not set drug prices as often happens in other countries.

First-time generics on the market can be expensive too, although not always as expensive as the brand. For example, currently, the only generic manufacturer for cyclosporine 0.05% ophthalmic is Mylan. Because they were the first to market, they do not have generic competition yet. However, as more manufacturers start to make generic cyclosporine, you should see the price go down even further.

Other brands for cyclosporine ophthalmic eye drops for dry eye include Cequa and Verkazia, but there are no generic alternatives for these products yet.

If you are having trouble affording your medication, speak to your healthcare provider, who may have other options. In addition, some manufacturers offer copay savings and other financial assistance for medicines. You can contact them directly.

Can dry eyes cause blurry vision? Which medications help?

Yes, dry eyes can cause blurry or fluctuating vision. This occurs because dry eye syndrome disrupts the tear film that coats the eye’s surface, leading to uneven light refraction and irregularities on the corneal surface. Meibomian gland dysfunction, which affects the oily layer of the tear film, is a major contributor to this problem.

Can you get Restasis eye drops over the counter?

No, Restasis (cyclosporine ophthalmic) eye drops require a prescription from your doctor, you cannot buy them over the counter (OTC). An optometrist or ophthalmologist are eye doctor specialists that usually prescribe this medicine. This drug is approved to treat dry eye disease. Continue reading

Are there any Restasis withdrawal symptoms?

Restasis withdrawal symptoms do not usually occur, but clinical studies have shown your persistent dry eye symptoms may return if you stop treatment. Depending upon your symptoms, you may need 3 to 6 months of Restasis treatment before your dry eyes start to improve. Restasis is typical meant for long-term use, but some patients may be able to stop treatment after 6 months. Continue reading

Why is Restasis so expensive?

Why are brand name drugs so expensive?

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Can dry eyes cause blurry vision? Which medications help?

Can you get Restasis eye drops over the counter?

Are there any Restasis withdrawal symptoms?

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