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Get key facts and figures about chronic dry eye

Medications for Dry Eye Disease (Keratoconjunctivitis Sicca)

Other names: Dry Eye Syndrome; Keratitis Sicca

About Dry Eye Disease:  A persistent dryness of the cornea and conjunctiva due to decreased function of the tear glands. the cornea may be thickened and visual acuity may be decreased. See also conjunctivitis, tearing, decreased, vitamin a deficiency, and sjogren syndrome.

Drugs Used to Treat Dry Eye Disease

The following list of medications are in some way related to, or used in the treatment of this condition.

Drug name Rx / OTC Pregnancy CSA Alcohol Reviews Rating Popularity
Restasis C N 123 reviews
4.0

Generic name: cyclosporine ophthalmic

Drug class: ophthalmic anti-inflammatory agents

For consumers: dosage, side effects

For professionals: AHFS DI Monograph, Prescribing Information

cyclosporine C N 132 reviews
4.0

Generic name: cyclosporine ophthalmic

Brand names:  Restasis, Cequa

Drug class: ophthalmic anti-inflammatory agents

For consumers: dosage,

For professionals: A-Z Drug Facts, AHFS DI Monograph

Xiidra N 91 reviews
4.0

Generic name: lifitegrast ophthalmic

Drug class: ophthalmic anti-inflammatory agents

For consumers: dosage, side effects

For professionals: AHFS DI Monograph, Prescribing Information

Cequa C N Add review Rate

Generic name: cyclosporine ophthalmic

Drug class: ophthalmic anti-inflammatory agents

For consumers: dosage, side effects

For professionals: Prescribing Information

Akwa Tears N N Add review Rate

Generic name: ocular lubricant ophthalmic

Drug class: ophthalmic lubricants and irrigations

For consumers: side effects

lifitegrast N 92 reviews
4.0

Generic name: lifitegrast ophthalmic

Brand name:  Xiidra

Drug class: ophthalmic anti-inflammatory agents

For consumers: dosage,

For professionals: A-Z Drug Facts, AHFS DI Monograph

Artificial Tears N N Add review Rate

Generic name: ocular lubricant ophthalmic

Drug class: ophthalmic lubricants and irrigations

For consumers: side effects

Celluvisc N N Add review Rate

Generic name: ocular lubricant ophthalmic

Drug class: ophthalmic lubricants and irrigations

For consumers: side effects

GenTeal N N Add review Rate

Generic name: ocular lubricant ophthalmic

Drug class: ophthalmic lubricants and irrigations

For consumers: side effects

Systane N N 7 reviews
2.0

Generic name: ocular lubricant ophthalmic

Drug class: ophthalmic lubricants and irrigations

For consumers: side effects

Systane Balance N N 3 reviews
4.0

Generic name: ocular lubricant ophthalmic

Drug class: ophthalmic lubricants and irrigations

For consumers: side effects

Altalube N N Add review Rate

Generic name: ocular lubricant ophthalmic

Drug class: ophthalmic lubricants and irrigations

For consumers: side effects

Bion Tears N N Add review Rate

Generic name: ocular lubricant ophthalmic

Drug class: ophthalmic lubricants and irrigations

For consumers: side effects

Clear Eyes Contact Lens Multi-Action Relief N N Add review Rate

Generic name: ocular lubricant ophthalmic

Drug class: ophthalmic lubricants and irrigations

For consumers: side effects

FreshKote N N 1 review
8.0

Generic name: ocular lubricant ophthalmic

Drug class: ophthalmic lubricants and irrigations

For consumers: side effects

Goniosoft N N Add review Rate

Generic name: hydroxypropyl methylcellulose ophthalmic

Drug class: ophthalmic lubricants and irrigations

For consumers: dosage, side effects

Goniosol N N Add review Rate

Generic name: hydroxypropyl methylcellulose ophthalmic

Drug class: ophthalmic lubricants and irrigations

For consumers: dosage, side effects

hydroxypropyl methylcellulose N N Add review Rate

Generic name: hydroxypropyl methylcellulose ophthalmic

Brand names:  Goniosoft, Goniosol, Gonak Hypromellose, Goniotaire, Goniovisc, ImproVue, OcuCoat …show all

Drug class: ophthalmic lubricants and irrigations

For consumers: dosage,

Hypotears N N Add review Rate

Generic name: ocular lubricant ophthalmic

Drug class: ophthalmic lubricants and irrigations

For consumers: side effects

Lacrisert N N 1 review Rate

Generic name: ocular lubricant ophthalmic

Drug class: ophthalmic lubricants and irrigations

For consumers: dosage, side effects

For professionals: Prescribing Information

Liquitears N N Add review Rate

Generic name: ocular lubricant ophthalmic

Drug class: ophthalmic lubricants and irrigations

For consumers: side effects

Oasis Tears N N Add review Rate

Generic name: ocular lubricant ophthalmic

Drug class: ophthalmic lubricants and irrigations

For consumers: side effects

Refresh N N Add review Rate

Generic name: ocular lubricant ophthalmic

Drug class: ophthalmic lubricants and irrigations

For consumers: side effects

Refresh Optive Mega-3 N N Add review Rate

Generic name: ocular lubricant ophthalmic

Drug class: ophthalmic lubricants and irrigations

For consumers: side effects

Refresh Tears N N 1 review
1.0

Generic name: ocular lubricant ophthalmic

Drug class: ophthalmic lubricants and irrigations

For consumers: side effects

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Learn more about Dry Eye Disease (Keratoconjunctivitis Sicca)

Symptoms and treatments

Legend

Off Label This medication may not be approved by the FDA for the treatment of this condition.
Prescription Only / Over the Counter
Rx Prescription Only
OTC Over the Counter
Rx/OTC Prescription or Over the Counter
Pregnancy
A Adequate and well-controlled studies have failed to demonstrate a risk to the fetus in the first trimester of pregnancy (and there is no evidence of risk in later trimesters).
B Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women.
C Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
D There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
X Studies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use in pregnant women clearly outweigh potential benefits.
N FDA has not classified the drug.
Controlled Substances Act Schedule
N Is not subject to the Controlled Substances Act.
1 Has a high potential for abuse. Has no currently accepted medical use in treatment in the United States. There is a lack of accepted safety for use under medical supervision.
2 Has a high potential for abuse. Has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse may lead to severe psychological or physical dependence.
3 Has a potential for abuse less than those in schedules 1 and 2. Has a currently accepted medical use in treatment in the United States. Abuse may lead to moderate or low physical dependence or high psychological dependence.
4 Has a low potential for abuse relative to those in schedule 3. It has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 3.
5 Has a low potential for abuse relative to those in schedule 4. Has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 4.
Alcohol
X Interacts with Alcohol.

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Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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