Skip to Content
Get key facts and figures about chronic dry eye

Medications for Dry Eye Disease

What is Dry Eye Disease: Dry eye disease occurs when there is reduced tear production or when tears evaporate too quickly due to a decrease in tear quality. Without sufficient lubrication the eyes become dry, with symptoms of grittiness, dryness, burning, redness or excessive tears.

Compare drugs associated with Dry Eye Disease

The following list of medications are in some way related to, or used in the treatment of this condition.

Drug name Rx / OTC Pregnancy CSA Alcohol Reviews Rating Popularity
lifitegrast Rx U 6 reviews
5.0

Generic name: lifitegrast ophthalmic

Brand name:  Xiidra

Drug class: ophthalmic anti-inflammatory agents

For consumers: dosage, side effects

For professionals: AHFS DI Monograph

 
Xiidra Rx U 6 reviews
5.0

Generic name: lifitegrast ophthalmic

Drug class: ophthalmic anti-inflammatory agents

For consumers: dosage, side effects

For professionals: AHFS DI Monograph, Prescribing Information

 
Artificial Tears Rx/OTC N N Add review Add

Generic name: ocular lubricant ophthalmic

Drug class: ophthalmic lubricants and irrigations

For consumers: side effects

 
Celluvisc Rx/OTC N N Add review Add

Generic name: ocular lubricant ophthalmic

Drug class: ophthalmic lubricants and irrigations

For consumers: side effects

 
Clear Eyes Contact Lens Multi-Action Relief Rx/OTC N N Add review Add

Generic name: ocular lubricant ophthalmic

Drug class: ophthalmic lubricants and irrigations

For consumers: side effects

 
FreshKote Rx/OTC N N Add review Add

Generic name: ocular lubricant ophthalmic

Drug class: ophthalmic lubricants and irrigations

For consumers: side effects

 
GenTeal Rx/OTC N N Add review Add

Generic name: ocular lubricant ophthalmic

Drug class: ophthalmic lubricants and irrigations

For consumers: side effects

 
hydroxypropyl methylcellulose Rx/OTC N N Add review Add

Generic name: hydroxypropyl methylcellulose ophthalmic

Drug class: ophthalmic lubricants and irrigations

For consumers: side effects

 
Hypotears Rx/OTC N N Add review Add

Generic name: ocular lubricant ophthalmic

Drug class: ophthalmic lubricants and irrigations

For consumers: side effects

 
Isopto Tears Rx/OTC N N Add review Add

Generic name: ocular lubricant ophthalmic

Drug class: ophthalmic lubricants and irrigations

For consumers: side effects

 
Lacri-Lube S.O.P. Rx/OTC N N Add review Add

Generic name: ocular lubricant ophthalmic

Drug class: ophthalmic lubricants and irrigations

For consumers: side effects

 
Lacrisert Rx/OTC N N 2 reviews
8.0

Generic name: ocular lubricant ophthalmic

Drug class: ophthalmic lubricants and irrigations

For consumers: dosage, side effects

For professionals: Prescribing Information

 
Liquitears Rx/OTC N N Add review Add

Generic name: ocular lubricant ophthalmic

Drug class: ophthalmic lubricants and irrigations

For consumers: side effects

 
Moisture Drops Rx/OTC N N Add review Add

Generic name: ocular lubricant ophthalmic

Drug class: ophthalmic lubricants and irrigations

For consumers: side effects

 
Murocel Rx/OTC N N Add review Add

Generic name: ocular lubricant ophthalmic

Drug class: ophthalmic lubricants and irrigations

For consumers: side effects

 
Oasis Tears Rx/OTC N N Add review Add

Generic name: ocular lubricant ophthalmic

Drug class: ophthalmic lubricants and irrigations

For consumers: side effects

 
ocular lubricant Rx/OTC N N 7 reviews
4.0

Generic name: ocular lubricant ophthalmic

Brand names:  Artificial Tears, Celluvisc, Clear Eyes Contact Lens Multi-Action Relief, FreshKote, GenTeal, Hypotears, Isopto Tears, Lacri-Lube S.O.P., Lacrisert, Liquitears, Moisture Drops, Murocel, Oasis Tears, Opti-Free Rewetting Drops, optive, Puralube Tears, Refresh, Soothe, Systane, Tears Again, TheraTears, Ultra Fresh, Visine Tears

Drug class: ophthalmic lubricants and irrigations

For consumers: side effects

For professionals: Prescribing Information

 
Opti-Free Rewetting Drops Rx/OTC N N Add review Add

Generic name: ocular lubricant ophthalmic

Drug class: ophthalmic lubricants and irrigations

For consumers: side effects

 
optive Rx/OTC N N Add review Add

Generic name: ocular lubricant ophthalmic

Drug class: ophthalmic lubricants and irrigations

For consumers: side effects

 
Puralube Tears Rx/OTC N N Add review Add

Generic name: ocular lubricant ophthalmic

Drug class: ophthalmic lubricants and irrigations

For consumers: side effects

 
Refresh Rx/OTC N N Add review Add

Generic name: ocular lubricant ophthalmic

Drug class: ophthalmic lubricants and irrigations

For consumers: side effects

 
Soothe Rx/OTC N N Add review Add

Generic name: ocular lubricant ophthalmic

Drug class: ophthalmic lubricants and irrigations

For consumers: side effects

 
Systane Rx/OTC N N 2 reviews
1.0

Generic name: ocular lubricant ophthalmic

Drug class: ophthalmic lubricants and irrigations

For consumers: side effects

 
Tears Again Rx/OTC N N Add review Add

Generic name: ocular lubricant ophthalmic

Drug class: ophthalmic lubricants and irrigations

For consumers: side effects

 
TheraTears Rx/OTC N N Add review Add

Generic name: ocular lubricant ophthalmic

Drug class: ophthalmic lubricants and irrigations

For consumers: side effects

 
Page 1 2 Next

Legend

Off Label This medication may not be approved by the FDA for the treatment of this condition.
Prescription Only / Over the Counter
Rx Prescription Only
OTC Over the Counter
Rx/OTC Prescription or Over the Counter
Pregnancy
A Adequate and well-controlled studies have failed to demonstrate a risk to the fetus in the first trimester of pregnancy (and there is no evidence of risk in later trimesters).
B Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women.
C Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
D There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
X Studies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use in pregnant women clearly outweigh potential benefits.
N FDA has not classified the drug.
Controlled Substances Act Schedule
N Is not subject to the Controlled Substances Act.
1 Has a high potential for abuse. Has no currently accepted medical use in treatment in the United States. There is a lack of accepted safety for use under medical supervision.
2 Has a high potential for abuse. Has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse may lead to severe psychological or physical dependence.
3 Has a potential for abuse less than those in schedules 1 and 2. Has a currently accepted medical use in treatment in the United States. Abuse may lead to moderate or low physical dependence or high psychological dependence.
4 Has a low potential for abuse relative to those in schedule 3. It has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 3.
5 Has a low potential for abuse relative to those in schedule 4. Has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 4.
Alcohol
X Interacts with Alcohol.

Browse Drugs by Condition

A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
Hide