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Eysuvis Side Effects

Generic name: loteprednol ophthalmic

Medically reviewed by Philip Thornton, DipPharm. Last updated on Apr 11, 2023.

Note: This document contains side effect information about loteprednol ophthalmic. Some dosage forms listed on this page may not apply to the brand name Eysuvis.

Applies to loteprednol ophthalmic: ophthalmic gel/jelly, ophthalmic ointment, ophthalmic suspension.

Serious side effects of Eysuvis

Along with its needed effects, loteprednol ophthalmic (the active ingredient contained in Eysuvis) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking loteprednol ophthalmic:

More common

Less common

Incidence not known

Other side effects of Eysuvis

Some side effects of loteprednol ophthalmic may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

For Healthcare Professionals

Applies to loteprednol ophthalmic: ophthalmic gel, ophthalmic ointment, ophthalmic suspension.


The most common reported side effects were anterior chamber inflammation, eye pain, and foreign body sensation.[Ref]


Common (1% to 10%): Corneal defect, eye discharge, ocular discomfort, dry eye, epiphora, foreign body sensation in eyes, conjunctival hyperemia, ocular itching, burning on instillation

Uncommon (0.1% to 1%): Abnormal vision, blurring of vision, chemosis, conjunctivitis, conjunctival hyperemia, iritis, eye irritation, eye pain, conjunctival papillae, photophobia, uveitis, keratoconjunctivitis

Frequency not reported: Elevated intraocular pressure, optic nerve damage, visual acuity and field defects, posterior subcapsular cataract formation[Ref]


Rare (less than 0.1%): Urticaria, rash, dry skin, eczema[Ref]


Rare (less than 0.1%): Diarrhea, nausea, vomiting[Ref]


Rare (less than 0.1%): Urinary tract infection, urethritis[Ref]


Rare (less than 0.1%): Weight gain[Ref]

Nervous system

Rare (less than 0.1%): Migraine, taste perversion, dizziness, paresthesia, tinnitus[Ref]


Rare (less than 0.1%): Breast neoplasm[Ref]


Uncommon (0.1% to 1%): Asthenia

Rare (less than 0.1%): Chills, fever, pain, face edema

Frequency not reported: Delayed wound healing[Ref]


Rare (less than 0.1%): Nervousness[Ref]


Uncommon (0.1% to 1%): Rhinitis, pharyngitis

Rare (less than 0.1%): Chest pain, cough[Ref]

Frequently asked questions


1. Product Information. Lotemax (loteprednol ophthalmic). Bausch and Lomb. 2001;PROD.

2. Product Information. Alrex (loteprednol ophthalmic). Bausch and Lomb. 2001;PROD.

3. Cerner Multum, Inc. UK Summary of Product Characteristics.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.