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Xiidra Side Effects

Generic Name: lifitegrast ophthalmic

Note: This page contains side effects data for the generic drug lifitegrast ophthalmic. It is possible that some of the dosage forms included below may not apply to the brand name Xiidra.

For the Consumer

Applies to lifitegrast ophthalmic: ophthalmic solution

As well as its needed effects, lifitegrast ophthalmic (the active ingredient contained in Xiidra) may cause unwanted side effects that require medical attention.

Major Side Effects

If any of the following side effects occur while taking lifitegrast ophthalmic, check with your doctor immediately:

More common:
  • Changes in vision
  • eye irritation or discomfort
Less common:
  • Blurred vision
  • redness of the white part of the eyes or inside of the eyelids

Minor Side Effects

Some lifitegrast ophthalmic side effects may not need any medical attention. As your body gets used to the medicine these side effects may disappear. Your health care professional may be able to help you prevent or reduce these side effects, but do check with them if any of the following side effects continue, or if you are concerned about them:

More common:
  • Change in taste
  • loss of taste
Less common:
  • Cough
  • discomfort or itching of the eyes
  • drainage from the eyes
  • fever
  • headache
  • pain or tenderness around the eyes and cheekbones
  • stuffy or runny nose
  • tightness of the chest
  • troubled breathing
  • watering of the eyes

For Healthcare Professionals

Applies to lifitegrast ophthalmic: ophthalmic solution

General

The most commonly reported side effects included instillation site irritation, dysgeusia, and reduced visual acuity.[Ref]

Ocular

Common (1% to 10%): Increased lacrimation, reduced visual acuity, blurred vision, conjunctival hyperemia, eye irritation, eye discharge/pruritus/discomfort[Ref]

Nervous system

Common (1% to 10%): Dysgeusia, headache[Ref]

Local

Common (1% to 10%): Instillation site irritation[Ref]

Respiratory

Common (1% to 10%): Sinusitis[Ref]

References

1. "Product Information. Xiidra (lifitegrast ophthalmic)." Shire US Inc, Florence, KY.

It is possible that some side effects of Xiidra may not have been reported. These can be reported to the FDA here. Always consult a healthcare professional for medical advice.

Disclaimer: Every effort has been made to ensure that the information provided is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate safety, effectiveness, or appropriateness for any given patient. Drugs.com does not assume any responsibility for any aspect of healthcare administered with the aid of materials provided. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the substances you are taking, check with your doctor, nurse, or pharmacist.

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