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Brivaracetam Side Effects

In Summary

Commonly reported side effects of brivaracetam include: acute psychosis, dizziness, drowsiness, equilibrium disturbance, fatigue, sedation, abnormal behavior, abnormal gait, aggressive behavior, agitation, anxiety, apathy, asthenia, ataxia, depressed mood, depression, hallucination, hypersomnia, lacrimation, lethargy, nervousness, nystagmus, paranoia, psychomotor agitation, vertigo, irritability, emotional lability, malaise, and restlessness. See below for a comprehensive list of adverse effects.

For the Consumer

Applies to brivaracetam: oral solution, oral tablet

Other dosage forms:

In addition to its needed effects, some unwanted effects may be caused by brivaracetam. In the event that any of these side effects do occur, they may require medical attention.

Major Side Effects

You should check with your doctor immediately if any of these side effects occur when taking brivaracetam:

More common:
  • Anxiety
  • changes in behavior
  • chest pain or discomfort
  • dizziness or lightheadedness
  • double vision
  • drowsiness
  • dry mouth
  • general feeling of discomfort or illness
  • hyperventilation
  • irregular heartbeats
  • irritability
  • nausea
  • restlessness
  • seeing double
  • sensation of spinning
  • sleepiness or unusual drowsiness
  • thoughts of killing oneself
  • trouble sleeping
  • unusual drowsiness, dullness, tiredness, weakness, or feeling of sluggishness
  • unusually deep sleep
  • unusually long duration of sleep
Less common:
  • Shakiness and unsteady walk
  • unsteadiness, trembling, or other problems with muscle control or coordination
  • uncontrolled eye movements
Incidence not known:
  • Cough
  • difficulty breathing or swallowing
  • fever
  • hives
  • large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs
  • noisy breathing
  • reddening of the skin, especially around the ears
  • swelling of the eyes, face, or inside of the nose

Minor Side Effects

Some of the side effects that can occur with brivaracetam may not need medical attention. As your body adjusts to the medicine during treatment these side effects may go away. Your health care professional may also be able to tell you about ways to reduce or prevent some of these side effects. If any of the following side effects continue, are bothersome or if you have any questions about them, check with your health care professional:

Less common:
  • Difficulty having a bowel movement (stool)
  • vomiting

For Healthcare Professionals

Applies to brivaracetam: intravenous solution, oral liquid, oral tablet


Common (1% to 10%): Nausea, vomiting, constipation[Ref]


Uncommon (0.1% to 1%): Neutropenia[Ref]


Common (1% to 10%): Influenza[Ref]


Common (1% to 10%): Decreased appetite, decreased weight[Ref]

Nervous system

Very common (10% or more): Somnolence/sedation (up to 16%), dizziness (up to 12%)
Common (1% to 10%): Fatigue, cerebellar coordination and balance disturbances, convulsion, vertigo[Ref]


Common (1% to 10%): Depression, anxiety, insomnia, irritability
Uncommon (0.1% to 1%): Suicidal ideation, psychotic disorder, aggression, agitation[Ref]


Common (1% to 10%): Upper respiratory tract infections, cough[Ref]


1. "Product Information. Briviact (brivaracetam)." UCB Pharma Inc, Smyrna, GA.

2. Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0

Not all side effects for brivaracetam may be reported. You should always consult a doctor or healthcare professional for medical advice. Side effects can be reported to the FDA here.

Disclaimer: Every effort has been made to ensure that the information provided is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate safety, effectiveness, or appropriateness for any given patient. does not assume any responsibility for any aspect of healthcare administered with the aid of materials provided. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the substances you are taking, check with your doctor, nurse, or pharmacist.