Ztalmy Side Effects
Generic name: ganaxolone
Medically reviewed by Drugs.com. Last updated on Mar 29, 2025.
Note: This document provides detailed information about Ztalmy.
Applies to ganaxolone: oral suspension Side Effects associated with ganaxolone. Some dosage forms listed on this page may not apply specifically to the brand name Ztalmy.
Applies to ganaxolone: oral suspension.
Precautions
It is very important that your doctor check your or your child's progress at regular visits to make sure this medicine is working properly and to check for unwanted effects.
Do not suddenly stop using this medicine without first checking with your doctor. Your doctor will need to slowly decrease your dose before you stop it completely. Stopping the medicine suddenly may cause your seizures to return or to occur more often.
This medicine may make you dizzy or drowsy. Do not drive or do anything else that could be dangerous until you know how this medicine affects you.
This medicine will add to the effects of alcohol and other CNS depressants (medicines that make you drowsy or less alert). Some examples of CNS depressants are antihistamines or medicine for hay fever, allergies, and colds, sedatives, tranquilizers, or sleeping medicine, prescription pain medicine or narcotics, medicine for seizures or barbiturates, muscle relaxants, or anesthetics (numbing medicines), including some dental anesthetics. This effect may last for a few days after you stop using this medicine. Check with your doctor or dentist before taking any of these medicines with ganaxolone (the active ingredient contained in Ztalmy) /i>.
If you or your child develop any unusual or strange thoughts and behavior while taking this medicine, be sure to discuss it with your doctor. Some of the changes that have occurred in people taking this medicine are like those seen in people who drink too much alcohol. Ganaxolone may cause confusion, worsening of depression, hallucinations (seeing, hearing, or feeling things that are not there), suicidal thoughts, and unusual excitement, nervousness, or irritability.
Do not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal or vitamin supplements.
Serious side effects of Ztalmy
Along with its needed effects, ganaxolone may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur while taking ganaxolone:
More common side effects
- relaxed and calm
- sleepiness or unusual drowsiness
Incidence not known
- changes in behavior
- discouragement
- feeling sad or empty
- irritability
- lack of appetite
- loss of interest or pleasure
- mood changes
- thoughts of killing oneself
- tiredness
- trouble concentrating
- trouble sleeping
Other side effects of Ztalmy
Some side effects of ganaxolone may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.
Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
More common side effects
Less common side effects
- diarrhea
- general feeling of discomfort or illness
- joint pain
- muscle aches and pains
- nausea
- shivering
- sweating
- vomiting
For healthcare professionals
Applies to ganaxolone: oral suspension.
Nervous system adverse events
- Very common (10% or more): Somnolence (included lethargy, hypersomnia; 38%)
- Common (1% to 10%): Sedation[Ref]
Other
- Very common (10% or more): Pyrexia (18%)
- Common (1% to 10%): Gait disturbance[Ref]
Respiratory
- Very common (10% or more): Upper respiratory tract infection (10%)
- Common (1% to 10%): Bronchitis, influenza, nasal congestion[Ref]
Gastrointestinal
- Common (1% to 10%): Salivary hypersecretion[Ref]
Hypersensitivity
See also:
Lamictal
Lamictal is an anti-epileptic medication used treat seizures in adults and children over 2 years ...
Lyrica
Lyrica is used to control seizures, treat nerve pain and fibromyalgia. Learn about side effects ...
Botox
Botox is used for cosmetic purposes and to treat overactive bladder symptoms, urinary incontinence ...
Depakote
Depakote is used to treat various types of seizure disorders. Learn about side effects ...
Carbamazepine
Carbamazepine is used to treat epileptic seizures and nerve pain such as trigeminal neuralgia ...
Diazepam
Diazepam is used to treat anxiety disorders, alcohol withdrawal symptoms, or muscle spasms. Learn ...
Levetiracetam
Levetiracetam systemic is used for bipolar disorder, epilepsy, hyperekplexia, neuralgia, new daily ...
Topiramate
Topiramate systemic is used for bipolar disorder, borderline personality disorder, bulimia ...
Pregabalin
Pregabalin may be used to treat certain types of pain and used in combination with other ...
Clonazepam
Clonazepam is used to treat seizures and panic disorder. Learn about side effects, interactions and ...
References
1. (2022) "Product Information. Ztalmy (ganaxolone)." Marinus Pharmaceuticals, Inc
More about Ztalmy (ganaxolone)
- Check interactions
- Compare alternatives
- Pricing & coupons
- Drug images
- Dosage information
- During pregnancy
- FDA approval history
- Drug class: gamma-aminobutyric acid analogs
- Breastfeeding
- En español
Patient resources
Professional resources
Related treatment guides
Further information
Ztalmy side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.
